MDMA

Executive Director

Molecular Masterclass: MDMA

PSYCHEDELICS AS MEDICINE

Making MDMA and Psilocybin-assisted therapies available in Australia- How to Access These Medicines Today to Treat Those With Serious Mental Illness

Book Launch For "Listening to Ecstasy"

Episode 10: Psychedelic-Assisted Psychotherapy for Eating Disorders and Cognitive Behavioural Therapies for PTSD + MDMA

The MDMA Conference

Drug Policy: From Illegal To Medical

Trip of Compassion: A Window Into Psychedelic-Assisted Therapies

WWC Conference- FREE global conference

Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain.

Non‐linear pharmacokinetics of MDMA ('ecstasy') in humans

Positron emission tomographic evidence of toxic effect of MDMA (“Ecstasy”) on brain serotonin neurons in human beings

The pharmacology and clinical pharmacology of 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”)

The molecular mechanism of" ecstasy": serotonin transporters are targets for MDMA-induced serotonin release.

Psychological and cardiovascular effects and short-term sequelae of MDMA (“ecstasy”) in MDMA-naıve healthy volunteers

Ecstasy (MDMA) effects upon mood and cognition: before, during and after a Saturday night dance

… effects of the serotonergic neurotoxicant (+/-)-3, 4-methylenedioxymethamphetamine (MDMA) correlates with the magnitude of the MDMA-induced thermal response.

Effects of dose, sex, and long-term abstention from use on toxic effects of MDMA (ecstasy) on brain serotonin neurons

'Eve'and'ecstasy': A report of five deaths associated with the use of MDEA and MDMA

MDMA-induced neurotoxicity: parameters of degeneration and recovery of brain serotonin neurons

Subjective reports on the effects of the MDMA (" ecstasy") experience in humans.

Small changes in ambient temperature cause large changes in 3, 4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body …

Neurochemistry and neurotoxicity of 3, 4‐methylenedioxymethamphetamine (MDMA,“ecstasy”)

Cognitive performance in (±) 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”) users: a controlled study

3, 4‐Methylenedioxymethamphetamine (MDMA,“Ecstasy”): pharmacology and toxicology in animals and humans

Review of the pharmacology and clinical pharmacology of 3, 4-methylenedioxymethamphetamine (MDMA or “Ecstasy”)

Memory impairment in abstinent MDMA (" Ecstasy") users

Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration

Gender differences in the subjective effects of MDMA

3, 4-Dihydroxymethamphetamine (HHMA). A major in vivo 3, 4-methylenedioxymethamphetamine (MDMA) metabolite in humans

Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain …

Serotonin neurotoxicity after (±) 3, 4-methylenedioxymethamphetamine (MDMA;“Ecstasy”): a controlled study in humans

Reorganization of ascending 5-HT axon projections in animals previously exposed to the recreational drug (+/-) 3, 4-methylenedioxymethamphetamine (MDMA," …

Mood and cognitive effects of±3, 4‐methylenedioxymethamphetamine (MDMA,'ecstasy'): week‐end 'high'followed by mid‐week low

Differences between the mechanism of action of MDMA, MBDB, and the classic hallucinogens. Identification of a new therapeutic class: entactogens

Pharmacologic profile of MDMA (3, 4-methylenedioxymethamphetamine) at various brain recognition sites

Cortical serotonin transporter density and verbal memory in individuals who stopped using 3, 4-methylenedioxymethamphetamine (MDMA or ecstasy): preliminary …

3, 4-Methylenedioxymethamphetamine (MDMA) neurotoxicity in rats: a reappraisal of past and present findings

Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition

The effects of 3, 4-methylenedioxymethamphetamine (MDMA) and 3, 4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the rat brain

Acute psychological effects of 3, 4-methylenedioxymethamphetamine (MDMA,“Ecstasy”) are attenuated by the serotonin uptake inhibitor citalopram

Cognitive performance in recreational users of MDMA or'ecstasy': Evidence for memory deficits

Which neuroreceptors mediate the subjective effects of MDMA in humans? A summary of mechanistic studies

Psychological and physiological effects of MDMA (“Ecstasy”) after pretreatment with the 5-HT 2 antagonist ketanserin in healthy humans

Self-administration of methylenedioxymethamphetamine (MDMA) by rhesus monkeys

The pharmacology of the acute hyperthermic response that follows administration of 3, 4‐methylenedioxymethamphetamine (MDMA,'ecstasy') to rats

The pharmacology and toxicology of “ecstasy”(MDMA) and related drugs

Determination of MDMA and its metabolites in blood and urine by gas chromatography-mass spectrometry and analysis of enantiomers by capillary electrophoresis

Memory deficits associated with recreational use of “ecstasy”(MDMA)

Subjective and hormonal effects of 3, 4-methylenedioxymethamphetamine (MDMA) in humans

Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research

The effects of methylenedioxymethamphetamine (MDMA,“Ecstasy”) on monoaminergic neurotransmission in the central nervous system

Is ecstasy MDMA? A review of the proportion of ecstasy tablets containing MDMA, their dosage levels, and the changing perceptions of purity

Reduced in vivo binding to the serotonin transporter in the cerebral cortex of MDMA ('ecstasy') users

Recreational MDMA use in Sydney: a profile of 'Ecstasy'users and their experiences with the drug

Effects of enantiomers of MDA, MDMA and related analogues on serotonin and dopamine release from superfused rat brain slices

A randomized, controlled pilot study of MDMA (±3, 4-Methylenedioxymethamphetamine)-assisted psychotherapy for treatment of resistant, chronic Post-Traumatic …

Severe dopaminergic neurotoxicity in primates after a common recreational dose regimen of MDMA (" ecstasy")

Aminergic Metabolites in Cerebrospinal Fluid of Humans Previously Exposed to MDMA: Preliminary Observationsa

Pharmacology of MDMA in humans

3, 4-methylenedioxymethamphetamine (MDMA,“Ecstasy”) induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro

Quantitative PET studies of the serotonin transporter in MDMA users and controls using McN5652 and DASB

Subjective reports of the effects of MDMA in a clinical setting

Stereochemical effects of 3, 4-methylenedioxymethamphetamine (MDMA) and related amphetamine derivatives on inhibition of uptake of monoamines into …

The origin of MDMA (ecstasy) revisited: the true story reconstructed from the original documents

MDMA (ecstasy') consumption in the context of polydrug abuse: a report on 150 patients

MDMA (ecstasy) inhibition of MAO type A and type B: comparisons with fenfluramine and fluoxetine (Prozac)

Ketanserin pretreatment attenuates MDMA-induced dopamine release in the striatum as measured by in vivo microdialysis

Neurotoxicity of MDMA and Related Compounds: Anatomic Studiesa

Toxicodynamics and long-term toxicity of the recreational drug, 3, 4-methylenedioxymethamphetamine (MDMA,'Ecstasy')

Recreational use of “ecstasy”(MDMA) is associated with elevated impulsivity

The hyperthermic and neurotoxic effects of 'Ecstasy'(MDMA) and 3, 4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor …

MDMA enhances emotional empathy and prosocial behavior

Ecstasy (MDMA): a review of its possible persistent psychological effects

Psychobiological problems in heavy 'ecstasy'(MDMA) polydrug users

Neurotoxicity of MDMA (ecstasy): the limitations of scaling from animals to humans

MDMA (ecstasy) and the rave: a review

Acute toxic effects of 'Ecstasy'(MDMA) and related compounds: overview of pathophysiology and clinical management

3, 4-Methylenedioxymethamphetamine (MDMA," ecstasy") and its stereoisomers as reinforcers in rhesus monkeys: serotonergic involvement

Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5‐HT levels in nucleus accumbens of awake rats

MDMA induced dopamine release in vivo: role of endogenous serotonin

Drug discrimination studies with MDMA and amphetamine

N-substituted piperazines abused by humans mimic the molecular mechanism of 3, 4-methylenedioxymethamphetamine (MDMA, or 'Ecstasy')

Impaired cognitive performance in drug free users of recreational ecstasy (MDMA)

Co-administration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat

Ecstasy, 3–4 methylenedioxymethamphetamine (MDMA), a fatality associated with coagulopathy and hyperthermia

MDMA (Ecstasy) and human dopamine, norepinephrine, and serotonin transporters: implications for MDMA-induced neurotoxicity and treatment

Working memory deficits in current and previous users of MDMA ('ecstasy')

The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA (ecstasy')

Chronic 3, 4-methylenedioxymethamphetamine (MDMA) use: effects on mood and neuropsychological function?

Multiple severe complications from recreational ingestion of MDMA ('ecstasy')

Simultaneous liquid chromatographic-electrospray ionization mass spectrometric quantification of 3, 4-methylenedioxymethamphetamine (MDMA, Ecstasy) and its …

Incidence of recreational use of 3, 4-methylenedimethoxymethamphetamine (MDMA," ecstasy") on an undergraduate campus.

Differences in the central serotonergic effects of methylenedioxymethamphetamine (MDMA) in mice and rats

Behavioral and neurochemical effects of orally administered MDMA in the rodent and nonhuman primate.

Low-dose MDMA (“ecstasy”) induces vasopressin secretion

Localization of MDMA‐induced brain activity in healthy volunteers using low resolution brain electromagnetic tomography (LORETA)

Serotonergic-dopaminergic mediation of 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”)

Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity

3,4-Methylenedioxymethamphetamine (MDMA): Stereoselective interactions at brain 5-HT1 and 5-HT2 receptors

3, 4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for post-traumatic stress disorder in military veterans, firefighters, and police officers: a …

Is MDMA ('Ecstasy') neurotoxic in humans? An overview of evidence and of methodological problems in research

Cocaine, MDMA and methamphetamine residues in wastewater: Consumption trends (2009–2015) in South East Queensland, Australia

MDMA elicits behavioral and neurochemical sensitization in rats

Effect of ecstasy on cerebral blood flow: a co-registered SPECT and MRI study

The background and chemistry of MDMA

MDMA ('ecstasy') use, and its association with high risk behaviors, mental health, and other factors among gay/bisexual men in New York City

Acute psychological and physiological effects of MDMA (“Ecstasy”) after haloperidol pretreatment in healthy humans

MDMA (“Ecstasy”) abuse and high-risk sexual behaviors among 169 gay and bisexual men

Self-injection of d,1-3,4-methylenedioxymethamphetamine (MDMA) in the baboon

Chronic MDMA (ecstasy) use, cognition and mood

The psychological and physiological effects of MDMA on normal volunteers

Ecstasy (MDMA) in recreational users: self‐reported psychological and physiological effects

Development, maintenance and temporal pattern of self-administration maintained by ecstasy (MDMA) in rats

A study of the neurotoxic effect of MDMA ('ecstasy') on 5‐HT neurones in the brains of mothers and neonates following administration of the drug during pregnancy

Ascorbic acid prevents 3, 4‐methylenedioxymethamphetamine (MDMA)‐induced hydroxyl radical formation and the behavioral and neurochemical consequences of …

Acute and subchronic effects of methylenedioxymethamphetamine on locomotion and serotonin syndrome behavior in the rat

Differences between rats and mice in MDMA (methylenedioxymethylamphetamine) neurotoxicity

In vivo evidence for free radical involvement in the degeneration of rat brain 5‐HT following administration of MDMA ('ecstasy') and p‐chloroamphetamine but not the …

Residual neuropsychological effects of illicit 3, 4-methylenedioxymethamphetamine (MDMA) in individuals with minimal exposure to other drugs

3, 4-Methylenedioxymethamphetamine (MDMA) as a unique model of serotonin receptor function and serotonin-dopamine interactions

The confounding problem of polydrug use in recreational ecstasy/MDMA users: a brief overview

Preliminary evidence of hippocampal dysfunction in adolescent MDMA (“ecstasy”) users: possible relationship to neurotoxic effects

MDMA induced hyperthermia: report of a fatality and review of current therapy

Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: cellular and molecular mechanisms

Analysis of 3, 4-methylenedioxymethamphetamine (MDMA) and its metabolites in plasma and urine by HPLC-DAD and GC-MS

Lasting effects of (+-)-3, 4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: neurochemical observations.

Pursuit of ecstasy: The MDMA experience

A review of the mechanisms involved in the acute MDMA (ecstasy)-induced hyperthermic response

Reinforcing, subjective, and physiological effects of MDMA in humans: a comparison with d-amphetamine and mCPP

Thermoregulatory effects of 3, 4-methylenedioxymethamphetamine (MDMA) in humans

Chronic tolerance to recreational MDMA (3, 4-methylenedioxymethamphetamine) or Ecstasy

Persistent effects of (±) 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”) on human sleep

Effects of MDMA on sociability and neural response to social threat and social reward

Neurotoxicity of MDMA: neurochemical effects

The pre-clinical behavioural pharmacology of 3, 4-methylenedioxymethamphetamine (MDMA)

A bitter pill. Overview of ecstasy (MDMA, MDA) related fatalities

Ecstasy (MDMA) dependence

Adverse reactions with 3, 4-methylenedioxymethamphetamine (MDMA;'ecstasy')

Memory impairment in abstinent MDMA (“ecstasy”) users: a longitudinal investigation

Effects of the selective 5-HT 2A receptor antagonist MDL 100,907 on MDMA-induced locomotor stimulation in rats

Reduced cortical gray matter density in human MDMA (Ecstasy) users: a voxel-based morphometry study

Increasing MDMA use among college students: results of a national survey

MDMA (“Ecstasy”) and its association with cerebrovascular accidents: preliminary findings

MDMA in humans: factors which affect the neuropsychobiological profiles of recreational ecstasy users, the integrative role of bioenergetic stress

3, 4-Methylenedioxymethamphetamine (MDMA) modulates cortical and limbic brain activity as measured by -PET in healthy humans

Mood, cognition and serotonin transporter availability in current and former ecstasy (MDMA) users: the longitudinal perspective

Causes and consequences of methamphetamine and MDMA toxicity

MDMA (3, 4-Methylenedioxymethamphetamine) or ecstasy: the neuropsychobiological implications of taking it at dances and raves

Elevated impulsivity and impaired decision-making cognition in heavy users of MDMA (“Ecstasy”)

Actions of 3, 4-methylenedioxymethamphetamine (MDMA) on cerebral dopaminergic, serotonergic and cholinergic neurons

MDMA enhances “mind reading” of positive emotions and impairs “mind reading” of negative emotions

Differential effects of MDMA, cocaine, and cannabis use severity on distinctive components of the executive functions in polysubstance users: a multiple regression …

MDMA: a review of epidemiological data

Repeated doses administration of MDMA in humans: pharmacological effects and pharmacokinetics

Effects of MDMA (ecstasy) on prepulse inhibition and habituation of startle in humans after pretreatment with citalopram, haloperidol, or ketanserin

The acute and chronic effects of MDMA (“ecstasy”) on cortical 5-HT 2A receptors in rat and human brain

The subjective effects of MDMA and mCPP in moderate MDMA users

Sub-acute effects of MDMA (±3, 4-methylenedioxymethamphetamine," ecstasy") on mood: evidence of gender differences

Ecstasy (MDMA): are the psychological problems associated with its use reversed by prolonged abstinence?

Acute, sub‐acute and long‐term subjective consequences of 'ecstasy'(MDMA) consumption in 430 regular users

“Partying” hard: party style, motives for and effects of MDMA use at rave parties

Electrophysiological evidence of serotonergic impairment in long-term MDMA (“ecstasy”) users

Acute and long-term effects of MDMA on cerebral dopamine biochemistry and function

A neurotoxic regimen of MDMA suppresses behavioral, thermal and neurochemical responses to subsequent MDMA administration

Respondent-driven sampling to recruit MDMA users: a methodological assessment

Chronic paranoid psychosis after misuse of MDMA (" ecstasy")

5‐HT loss in rat brain following 3, 4‐methylenedioxymethamphetamine (MDMA), p‐chloroamphetamine and fenfluramine administration and effects of …

Increased intensity of Ecstasy and polydrug usage in the more experienced recreational Ecstasy/MDMA users: a WWW study

MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized …

A study of the mechanisms involved in the neurotoxic action of 3, 4‐methylenedioxymethamphetamine (MDMA,'ecstasy') on dopamine neurones in mouse brain

Effect of GBR 12909 and fluoxetine on the acute and long term changes induced by MDMA ('ecstasy') on the 5-HT and dopamine concentrations in mouse brain

Neurotoxicity of methylenedioxyamphetamines (MDMA; ecstasy) in humans: how strong is the evidence for persistent brain damage?

Subjective effects of MDMA ('Ecstasy') on human sexual function

Neuroendocrine and mood responses to intravenous L-tryptophan in 3, 4-methylenedioxymethamphetamine (MDMA) users: preliminary observations

Hyperpyrexia and rhaddomyolysis after MDMA (ecstasy) abuse

Neurochemical and neurohistological alterations in the rat and monkey produced by orally administered methylenedioxymethamphetamine (MDMA)

Recreational ecstasy/MDMA and other drug users from the UK and Italy: psychiatric symptoms and psychobiological problems

Ecstasy/MDMA attributed problems reported by novice, moderate and heavy recreational users

Striatal serotonin is depleted in brain of a human MDMA (Ecstasy) user

In vivo detection of short‐and long‐term MDMA neurotoxicity—a positron emission tomography study in the living baboon brain

Increased anxiety 3 months after brief exposure to MDMA ('Ecstasy') in rats: association with altered 5-HT transporter and receptor density

Effect of ambient temperature on hyperthermia and hyperkinesis induced by 3, 4-methylenedioxymethamphetamine (MDMA or “ecstasy”) in rats

A review of the acute subjective effects of MDMA/ecstasy

Human research on MDMA (3, 4-methylene-dioxymethamphetamine) neurotoxicity: cognitive and behavioural indices of change

Mood, cognition and serotonin transporter availability in current and former ecstasy (MDMA) users

Level of use of 3, 4-methylenedioxymethamphetamine (MDMA or Ecstasy) in humans correlates with EEG power and coherence

MDMA ('ecstasy') and other'club drugs'. The new epidemic.

Hyperthermia following MDMA administration in rats: effects of ambient temperature, water consumption, and chronic dosing

α-Lipoic acid prevents 3, 4-methylenedioxy-methamphetamine (MDMA)-induced neurotoxicity

Effects of MDMA (ecstasy), and multiple drugs use on (simulated) driving performance and traffic safety

Pharmacokinetic and pharmacodynamic effects of methylphenidate and MDMA administered alone or in combination

How could MDMA (ecstasy) help anxiety disorders? A neurobiological rationale

Memory deficits in abstinent MDMA (ecstasy) users: neuropsychological evidence of frontal dysfunction

Acute effects of 3, 4-methylenedioxymethamphetamine (MDMA) on behavioral measures of impulsivity: alone and in combination with alcohol

MDMA (“Ecstasy”) and panic disorder: induction by a single dose

Acute effects of 3, 4-methylenedioxymethamphetamine (MDMA) on monoamines in rat caudate

Role of hyperthermia in the protective action of clomethiazole against MDMA ('ecstasy')‐induced neurodegeneration, comparison with the novel NMDA channel …

MDMA (“ecstasy”), methamphetamine and their combination: long-term changes in social interaction and neurochemistry in the rat

A method of conducting therapeutic sessions with MDMA

Long-term neuropsychiatric consequences of" ecstasy"(MDMA): a review

Opposite effects of 3, 4-methylenedioxymethamphetamine (MDMA) on sensorimotor gating in rats versus healthy humans

Duloxetine Inhibits Effects of MDMA (“Ecstasy") In Vitro and in Humans in a Randomized Placebo-Controlled Laboratory Study

Club drugs: MDMA, gamma-hydroxybutyrate (GHB), Rohypnol, and ketamine

Fatal interaction between ritonavir and MDMA

Construct validity of the balloon analogue risk task (BART): Relationship with MDMA use by inner-city drug users in residential treatment

Behavioral and neurochemical consequences of long-term intravenous self-administration of MDMA and its enantiomers by rhesus monkeys

Cerebral 1H MRS alterations in recreational 3,4‐methylenedioxymethamphetamine (MDMA, “ecstasy”) users

… in the degeneration of 5‐HT nerve endings in the brain of Dark Agouti rats following 3, 4‐methylenedioxymethamphetamine (MDMA or 'ecstasy') administration

The complications of'ecstasy'(MDMA)

Cognitive function and mood in MDMA/THC users, THC users and non-drug using controls

The abused drug MDMA (Ecstasy) induces programmed death of human serotonergic cells

Long-term changes in social interaction and reward following repeated MDMA administration to adolescent rats without accompanying serotonergic neurotoxicity

Neuropsychological evidence of a relatively selective profile of temporal dysfunction in drug-free MDMA (" ecstasy") polydrug users

Recreational use of 3, 4-methylenedioxymethamphetamine (MDMA) or'ecstasy': evidence for cognitive impairment

The mechanisms involved in the long‐lasting neuroprotective effect of fluoxetine against MDMA ('ecstasy')‐induced degeneration of 5‐HT nerve endings in rat brain

MDMA: Nonmedical use and intoxication

(±)-3, 4-Methylenedioxymethamphetamine (MDMA,'Ecstasy') increases social interaction in rats

Structure of continuously cooled low-carbon vanadium steels

MDMA polydrug users show processspecific central executive impairments coupled with impaired social and emotional judgement processes

Behavioural analysis of the acute and chronic effects of MDMA treatment in the rat

Reward-related decision-making deficits and elevated impulsivity among MDMA and other drug users

Locomotor response to MDMA is attenuated in knockout mice lacking the 5-HT1B receptor

Human psychobiology of MDMA or 'Ecstasy': an overview of 25 years of empirical research

MDMA use and neurocognition: a meta-analytic review

Fatalities caused by the MDMA-related drug paramethoxyamphetamine (PMA)

The norepinephrine transporter inhibitor reboxetine reduces stimulant effects of MDMA (“ecstasy”) in humans

MDMA (Ecstasy) neurotoxicity: assessing and communicating the risks

Contribution of cannabis and MDMA (" ecstasy") to cognitive changes in long-term polydrug users

Importance of ERK activation in behavioral and biochemical effects induced by MDMA in mice

The psychotherapeutic potential of MDMA (3, 4-methylenedioxymethamphetamine): an evidence-based review

MDMA-assisted psychotherapy using low doses in a small sample of women with chronic posttraumatic stress disorder

Fatal multi-organ failure after suicidal overdose with MDMA,Ecstasy': case report and review of the literature

Long term psychiatric and cognitive effects of MDMA use

Methylenedioxymethamphetamine (MDMA,'Ecstasy'): a stressor on the immune system

Development of a lidar system for measuring methane using a gas correlation method

Altered neuroendocrine and behavioral responses to m-chlorophenylpiperazine in 3, 4-methylenedioxymethamphetamine (MDMA) users

Distribution of 3, 4-methylenedioxymethamphetamine (MDMA) and 3, 4-methylenedioxyamphetamine (MDA) stereoisomers in a fatal poisoning

Methylphenidate and MDMA adolescent exposure in mice: long-lasting consequences on cocaine-induced reward and psychomotor stimulation in adulthood

Brain hyperthermia induced by MDMA ('ecstasy'): modulation by environmental conditions

Demonstration and localization of neuronal degeneration in the rat forebrain following a single exposure to MDMA

mechanisms and management of hepatotoxicity in ecstasy (MDMA) and amphetamine intoxications.

Neurotoxic effects of MDMA on brain serotonin neurons: evidence from neurochemical and radioligand binding studies.

The effects of fluoxetine on the subjective and physiological effects of 3, 4-methylenedioxymethamphetamine (MDMA) in humans

A comprehensive review of MDMA and GHB: two common club drugs

Lack of serotonin neurotoxicity after intraraphe microinjection of (+)-3, 4-methylenedioxymethamphetamine (MDMA)

A clinical plan for MDMA (Ecstasy) in the treatment of posttraumatic stress disorder (PTSD): partnering with the FDA

Differential contributions of dopamine D 1, D 2, and D 3 receptors to MDMA-induced effects on locomotor behavior patterns in mice

Increased anxiety and" depressive" symptoms months after MDMA (" ecstasy") in rats: drug-induced hyperthermia does not predict long-term outcomes

Neuroanatomic specificity and time course of alterations in rat brain serotonergic pathways induced by MDMA (3, 4‐methylenedioxymethamphetamine): assessment …

Assessment of the discriminative stimulus effects of the optical isomers of ecstasy (3, 4-methylenedioxymethamphetamine; MDMA).

Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ('Ecstasy') to rats

Life-threatening interactions between HIV-1 protease inhibitors and the illicit drugs MDMA and γ-hydroxybutyrate

Hippocampal serotonergic damage induced by MDMA (ecstasy): effects on spatial learning

Hyponatraemic states following 3, 4‐methylenedioxymethamphetamine (MDMA,'ecstasy') ingestion

Impulsivity, risk taking and recreational 'ecstasy'(MDMA) use

MDMA and human sexual function

MDMA (Ecstasy) precipitation of panic disorder

Memory function and serotonin transporter promoter gene polymorphism in ecstasy (MDMA) users

Reinforcing effects of MDMA ('ecstasy') in drug-naive and cocaine-trained rats

Concurrent use of methamphetamine, MDMA, LSD, ketamine, GHB, and flunitrazepam among American youths

Influence of inducers and inhibitors on the metabolism in vitro and neurochemical effects in vivo of MDMA.

Ecstasy: The complete guide: A comprehensive look at the risks and benefits of MDMA

Death following ingestion of MDMA (ecstasy) and moclobemide

Memory deficit and reduced anxiety in young adult rats given repeated intermittent MDMA treatment during the periadolescent period

MDMA and sexual behavior: Ecstasy users' perceptions about sexuality and sexual risk

3, 4‐methylenedioxymethamphetamine (MDMA) administration to rats decreases brain tissue serotonin but not serotonin transporter protein and glial fibrillary acidic …

Serotonin–GABA interactions modulate MDMA‐induced mesolimbic dopamine release

Potential human neurotoxicity of MDMA ('Ecstasy'): subjective self-reports, evidence from an Italian drug addiction centre and clinical case studies

Chronic fluoxetine treatment partly attenuates the long-term anxiety and depressive symptoms induced by MDMA ('Ecstasy') in rats

Cerebral oedema after ingestion of MDMA (“ecstasy”) and unrestricted intake of water

MDMA self‐administration in rats: acquisition, progressive ratio responding and serotonin transporter binding

MDMA-assisted psychotherapy for PTSD: are memory reconsolidation and fear extinction underlying mechanisms?

Implications of mechanism-based inhibition of CYP2D6 for the pharmacokinetics and toxicity of MDMA

Rapid analysis of amphetamine, methamphetamine, MDA, and MDMA in urine using solid-phase microextraction, direct on-fiber derivatization, and analysis by GC …

Differential effects of MDMA and methylphenidate on social cognition

The effects of MDMA and other methylenedioxy-substituted phenylalkylamines on the structure of rat locomotor activity.

MDMA ('ecstasy') enhances basal acetylcholine release in brain slices of the rat striatum

A role for the mesolimbic dopamine system in the psychostimulant actions of MDMA

Ecstacy: a review of MDMA and MDA

Multiple 5-HT receptors are involved in the effects of acute MDMA treatment: studies on locomotor activity and responding for conditioned reinforcement

Estimating the relative reinforcing strength of (±)-3, 4-methylenedioxymethamphetamine (MDMA) and its isomers in rhesus monkeys: comparison to (+) …

Chronic atypical psychosis associated with MDMA (ecstasy) abuse

MDMA: the dark side of Ecstasy

Locomotor stimulation produced by 3, 4-methylenedioxymethamphetamine (MDMA) is correlated with dialysate levels of serotonin and dopamine in rat brain

Causes and consequences of the loss of serotonergic presynapses elicited by the consumption of 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”) and its …

MDMA and alcohol effects, combined and alone, on objective and subjective measures of actual driving performance and psychomotor function

The spatial epidemiology of cocaine, methamphetamine and 3, 4‐methylenedioxymethamphetamine (MDMA) use: a demonstration using a population measure of …

Neuroimaging research in human MDMA users: a review

Effects of MDMA and intranasal oxytocin on social and emotional processing

Acute psychological and neurophysiological effects of MDMA in humans

Superoxide radicals mediate the biochemical effects of methylenedioxymethamphetamine (MDMA): evidence from using CuZn‐superoxide dismutase transgenic mice

Prepulse inhibition and habituation of acoustic startle response in male MDMA ('ecstasy') users, cannabis users, and healthy controls

Effect of 3, 4-methylenedioxymethamphetamine (MDMA) on hippocampal dopamine and serotonin

Persistent MDMA‐induced dopaminergic neurotoxicity in the striatum and substantia nigra of mice

MDMA (Ecstasy') enhances 5-HT1A receptor density and 8-OH-DPAT-induced hypothermia: blockade by drugs preventing 5-hydroxytryptamine depletion

Caffeine promotes hyperthermia and serotonergic loss following co-administration of the substituted amphetamines, MDMA (“Ecstasy”) and MDA (“Love”)

Symptoms of anxiety and depression in childhood and use of MDMA: prospective, population based study

Profiles of urine samples from participants at rave party in Taiwan: prevalence of ketamine and MDMA abuse

Reduction in social anxiety after MDMA-assisted psychotherapy with autistic adults: a randomized, double-blind, placebo-controlled pilot study

Impaired executive function in male MDMA (“ecstasy”) users

Agony and ecstasy: a review of MDMA effects and toxicity

Elevation of ambient room temperature has differential effects on MDMA-induced 5-HT and dopamine release in striatum and nucleus accumbens of rats

MDMA (3, 4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin

Quantitative and qualitative analysis of MDMA, MDEA, MA and amphetamine in urine by head-space/solid phase micro-extraction (SPME) and GC/MS

MDMA (ecstasy) effects on cultured serotonergic neurons: evidence for Ca2+-dependent toxicity linked to release

The threshold lowering effects of MDMA (ecstasy) on brain-stimulation reward

Former chronic methylenedioxymethamphetamine (MDMA or ecstasy) users report mild depressive symptoms

… dismutase (CuZnSOD) transgenic mice show resistance to the lethal effects of methylenedioxyamphetamine (MDA) and of methylenedioxymethamphetamine (MDMA …

Increasing use of “ecstasy “(MDMA) and other hallucinogens on a college campus

Stimulant effects of 3, 4‐methylenedioxymethamphetamine (MDMA) 75 mg and methylphenidate 20 mg on actual driving during intoxication and withdrawal

Dance clubbing on MDMA and during abstinence from Ecstasy/MDMA: prospective neuroendocrine and psychobiological changes

Toxic effect of MDMA on brain serotonin neurons

Cell‐mediated immune response in MDMA users after repeated dose administration: studies in controlled versus noncontrolled settings

Pharmacokinetic profile of single and repeated oral doses of MDMA in squirrel monkeys: relationship to lasting effects on brain serotonin neurons

Oxytocin-dependent reopening of a social reward learning critical period with MDMA

The role of monoamines in the changes in body temperature induced by 3, 4‐methylenedioxymethamphetamine (MDMA, ecstasy) and its derivatives

A neurotoxic dose of 3, 4-methylenedioxymethamphetamine (MDMA; ecstasy) to rats results in a long term defect in thermoregulation

MDMA (“ecstasy”) abuse: psychopathological features and craving for chocolate: a case series

Neurotoxicity of drugs of abuse-the case of methylenedioxy amphetamines (MDMA, ecstasy), and amphetamines

Role of the endocannabinoid system in MDMA intracerebral self‐administration in rats

3, 4-Methylenedioxymethamphetamine (MDMA) abuse may cause oxidative stress and potential free radical damage

Increased sensitivity to the acute effects of MDMA (“ecstasy”) in female rats

… amphetamine, methamphetamine, methylenedioxyamphetamine (MDA), methylenedioxymethamphetamine (MDMA), and methylenedioxyethylamphetamine (MDEA) …

… neurotoxic dose of 3, 4-methylenedioxymethamphetamine (MDMA) on the hyperthermic response of rats to a single or repeated ('binge'ingestion) low dose of MDMA

Subarachnoid haemorrhage associated with MDMA abuse.

Effects of the serotonin releasers 3, 4-methylenedioxymethamphetamine (MDMA), 4-chloroamphetamine (PCA) and fenfluramine on acoustic and tactile startle …

Reserpine attenuates D-amphetamine and MDMA-induced transmitter release in vivo: a consideration of dose, core temperature and dopamine synthesis

The effect of 3, 4‐methylenedioxymethamphetamine (MDMA,? ecstasy?) and its metabolites on neurohypophysial hormone release from the isolated rat …

Detection of “bath salts” and other novel psychoactive substances in hair samples of ecstasy/MDMA/“Molly” users

A direct comparison of the behavioral and physiological effects of methamphetamine and 3, 4-methylenedioxymethamphetamine (MDMA) in humans

Role of metabolites in MDMA (ecstasy)-induced nephrotoxicity: an in vitro study using rat and human renal proximal tubular cells

Effect of the R (−) and S (+) isomers of MDA and MDMA on phosphotidyl inositol turnover in cultured cells expressing 5-HT2A or 5-HT2C receptors

Immunomodulating properties of MDMA alone and in combination with alcohol: a pilot study

Effect of MDMA (ecstasy) on activity and cocaine conditioned place preference in adult and adolescent rats

Physiological and subjective responses to controlled oral MDMA administration

A study of the effect of a single neurotoxic dose of 3, 4-methylenedioxymethamphetamine (MDMA;" ecstasy") on the subsequent long-term behaviour of rats in the plus …

The agony of ecstasy: MDMA (3, 4-methylenedioxymethamphetamine) and the kidney

Orally administered MDMA causes a long-term depletion of serotonin in rat brain

Psychosocial profiles of older adolescent MDMA users

Safety pharmacology of acute MDMA administration in healthy subjects

Cannabis and Ecstasy/MDMA (3, 4-methylenedioxymethamphetamine): an analysis of their neuropsychobiological interactions in recreational users

Effects of repeated doses of MDMA (“ecstasy”) on cell-mediated immune response in humans

Effects of MDMA exposure on the conditioned place preference produced by other drugs of abuse

Toxicity of MDA (3, 4-methylenedioxyamphetamine) considered for relevance to hazards of MDMA (Ecstasy) abuse.

Cannabinoids prevent the acute hyperthermia and partially protect against the 5-HT depleting effects of MDMA (“Ecstasy”) in rats

Persistent loss of thermoregulation in the rat induced by 3, 4-methylenedioxymethamphetamine (MDMA or “Ecstasy”) but not by fenfluramine

MDMA ('Ecstasy') and methamphetamine combined: order of administration influences hyperthermic and long-term adverse effects in female rats

Involvement of free radicals in MDMA-induced neurotoxicity in mice.

MDMA produces a conditioned place preference and elicits ejaculation in male rats: a modulatory role for the endogenous opioids

A comparative study on the acute and long‐term effects of MDMA and 3, 4‐dihydroxymethamphetamine (HHMA) on brain monoamine levels after ip or striatal …

Ecstasy (MDMA) deaths in New York City: a case series and review of the literature

Serotonin (1A) receptor involvement in acute 3, 4-methylenedioxymethamphetamine (MDMA) facilitation of social interaction in the rat

Elevated impulsivity and impaired decision-making in abstinent Ecstasy (MDMA) users compared to polydrug and drug-naive controls

A comparison of the reinforcing efficacy of 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”) with cocaine in rhesus monkeys

Dissociable effects of a single dose of ecstasy (MDMA) on psychomotor skills and attentional performance

Self-reported psychopathological symptoms in recreational ecstasy (MDMA) users are mainly associated with regular cannabis use: further evidence from a combined …

MDMA, serotonergic neurotoxicity, and the diverse functional deficits of recreational 'Ecstasy'users

Role of serotonin via 5-HT 2B receptors in the reinforcing effects of MDMA in mice

Functional MRI study of working memory in MDMA users

Behavioral and neurochemical effects of prenatal methylenedioxymethamphetamine (MDMA) exposure in rats

Direct effects of 3, 4‐methylenedioxymethamphetamine (MDMA) on serotonin or dopamine release and uptake in the caudate putamen, nucleus accumbens …

3, 4-Methylenedioxymethamphetamine (MDMA, ecstasy) and driving impairment

Effect of Repeated ('Binge') Dosing of MDMA to Rats Housed at Normal and High Temperature on Neurotoxicdamage to Cerebral 5-Ht and Dopamine Neurones

Psychiatric disorders in Ecstasy (MDMA) users: a literature review focusing on personal predisposition and drug history

Acute toxicity of 3, 4-methylenedioxymethamphetamine (MDMA) in Sprague–Dawley and Dark Agouti rats

Death rates from ecstasy (MDMA, MDA) and polydrug use in England and Wales 1996–2002

Effects of dopamine D1- or D2-like receptor antagonists on the hypermotive and discriminative stimulus effects of (+)-MDMA

The neuropsychology of ecstasy (MDMA) use: a quantitative review

Is a single dose of MDMA harmless

MDMA: its history and pharmacology

Rewarding effects and reinstatement of MDMA-induced CPP in adolescent mice

Acute and long-term consequences of single MDMA administration in relation to individual anxiety levels in the rat

Fatal poisoning by MDMA (ecstasy) and MDEA: a case report

High intensity dependence of auditory evoked dipole source activity indicates decreased serotonergic activity in abstinent ecstasy (MDMA) users

MDMA and temperature: a review of the thermal effects of 'Ecstasy'in humans

Simultaneous analysis of six amphetamines and analogues in hair, blood and urine by LC-ESI-MS/MS: application to the determination of MDMA after low Ecstasy …

Decreased social behaviour following 3, 4-methylenedioxymethamphetamine (MDMA) is accompanied by changes in 5-HT2A receptor responsivity

A contribution to the chemical profiling of 3, 4-methylenedioxymethamphetamine (MDMA) tablets

Repeated weekly exposure to MDMA, methamphetamine or their combination: long-term behavioural and neurochemical effects in rats

Administration of SCH 23390 into the medial prefrontal cortex blocks the expression of MDMA-induced behavioral sensitization in rats: an effect mediated by 5 …

The therapeutic use of MDMA

Distinct acute effects of LSD, MDMA, and D-amphetamine in healthy subjects

A study of the mechanism of MDMA ('Ecstasy')‐induced neurotoxicity of 5‐HT neurones using chlormethiazole, dizocilpine and other protective compounds

Relevance of MDMA (" ecstasy")-induced neurotoxicity to long-lasting psychomotor stimulation in mice

Gender differences in self-reported anxiety, depression, and somatization among ecstasy/MDMA polydrug users, alcohol/tobacco users, and nondrug users

Stability study of the designer drugs “MDA, MDMA and MDEA” in water, serum, whole blood, and urine under various storage temperatures

Neuroimaging findings with MDMA/ecstasy: technical aspects, conceptual issues and future prospects

Psychomotor stimulant effects ofd-amphetamine, MDMA and PCP: aggressive and schedule-controlled behavior in mice

Effects of acute MDMA intoxication on mood and impulsivity: role of the 5-HT 2 and 5-HT 1 receptors

Studies on the effect of MDMA ('ecstasy') on the body temperature of rats housed at different ambient room temperatures

Loss of serotonin transporter protein after MDMA and other ring-substituted amphetamines

The anxiogenic-like and anxiolytic-like effects of MDMA on mice in the elevated plus-maze: a comparison with amphetamine

Neuropsychological effects of 3, 4-methylenedioxymethamphetamine (MDMA or ecstasy) in recreational users

Chemical profiling of 3, 4-methylenedioxymethamphetamine (MDMA) tablets seized in Hong Kong

Effect of MDMA neurotoxicity upon its conditioned place preference and discrimination

Repeated MDMA (“ecstasy”) exposure in adolescent male rats alters temperature regulation, spontaneous motor activity, attention, and serotonin transporter binding

MDMA-assisted therapy: a new treatment model for social anxiety in autistic adults

Treating posttraumatic stress disorder with MDMA-assisted psychotherapy: a preliminary meta-analysis and comparison to prolonged exposure therapy

Exposure to 3, 4-methylenedioxymethamphetamine (MDMA) on postnatal days 11–20 induces reference but not working memory deficits in the Morris water maze in …

Brain concentrations of d-MDMA are increased after stress

Structure-activity relationship of MDMA and related compounds: A new class of psychoactive drugs?

A reliable model of intravenous MDMA self-administration in naive mice

Psychological profile of abstinent recreational Ecstasy (MDMA) users and significance of concomitant cannabis use

Discriminative profile of MDMA

Pill content, dose and resulting plasma concentrations of 3, 4‐methylendioxymethamphetamine (MDMA) in recreational 'ecstasy'users

Nantenine: an antagonist of the behavioral and physiological effects of MDMA in mice

Differential effects of intravenous R, S‐(±)‐3, 4‐methylenedioxymethamphetamine (MDMA, Ecstasy) and its S (+)‐and R (−)‐enantiomers on dopamine transmission …

Effects of cortical serotonin depletion induced by 3, 4-methylenedioxymethamphetamine (MDMA) on behavior, before and after additional cholinergic blockade

An exploration of the history and controversies surrounding MDMA and MDA

Changes in serotonin, dopamine and noradrenaline levels in striatum and nucleus accumbens after repeated administration of the abused drug MDMA in rats

A review of 3, 4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy

Dopamine D2-receptor knockout mice are protected against dopaminergic neurotoxicity induced by methamphetamine or MDMA

Mechanism of 3, 4‐methylenedioxymethamphetamine (MDMA, ecstasy)‐mediated mitochondrial dysfunction in rat liver

Oral administration of 3, 4-methylenedioxymethamphetamine (MDMA) produces selective serotonergic depletion in the nonhuman primate

Neuropsychiatric manifestations following the use of 3, 4-methylenedioxymethamphetamine (MDMA:" Ecstasy").

Acute dose of MDMA (75 mg) impairs spatial memory for location but leaves contextual processing of visuospatial information unaffected

Investigation of the prejunctional α2‐adrenoceptor mediated actions of MDMA in rat atrium and vas deferens

Study of the behavioural responses related to the potential addictive properties of MDMA in mice

MDA-MDMA concentrations in urine specimens

In vivo imaging of cerebral serotonin transporter and serotonin2A receptor binding in 3, 4-methylenedioxymethamphetamine (MDMA or “ecstasy”) and hallucinogen …

Interpretation of a 3, 4-methylenedioxymethamphetamine (MDMA) blood level: discussion by means of a distribution study in two fatalities

Cardiovascular and sympathetic responses and reflex changes elicited by MDMA

Fast LC–MS/MS method for the determination of amphetamine, methamphetamine, MDA, MDMA, MDEA, MBDB and PMA in urine

Functional consequences of repeated (±) 3, 4-methylenedioxymethamphetamine (MDMA) treatment in rhesus monkeys

Visuospatial memory impairments in users of MDMA ('ecstasy')

Ecstasy (MDMA, MDA, MDEA, MBDB) consumption, seizures, related offences, prices, dosage levels and deaths in the UK (1994–2003)

Acute 3, 4-methylenedioxymethamphetamine (MDMA) administration produces a rapid and sustained suppression of immune function in the rat

Modeling in vitro inhibition of butyrylcholinesterase using molecular docking, multi-linear regression and artificial neural network approaches

Developmental 3, 4-methylenedioxymethamphetamine (MDMA) impairs sequential and spatial but not cued learning independent of growth, litter effects or injection …

Multifaceted empathy of healthy volunteers after single doses of MDMA: a pooled sample of placebo-controlled studies

Cerebral activation in abstinent ecstasy (MDMA) users during a working memory task: a functional magnetic resonance imaging (fMRI) study

The potential dangers of using MDMA for psychotherapy

Neurocognitive function in users of MDMA: the importance of clinically significant patterns of use

MDMA‐induced neurotoxicity: long‐term effects on 5‐HT biosynthesis and the influence of ambient temperature

Therapeutic effect of increased openness: Investigating mechanism of action in MDMA-assisted psychotherapy

Early loss of dopaminergic terminals in striosomes after MDMA administration to mice

Tissue concentrations of MDMA and its metabolite MDA in three fatal cases of overdose

Impurity profiling of seized MDMA tablets by capillary gas chromatography

The neurotoxic effects of 3, 4-methylenedioxymethamphetamine (MDMA) and methamphetamine on serotonin, dopamine, and GABA-ergic terminals: an in-vitro …

… of a single dose of 3, 4-methylenedioxymethamphetamine on circadian patterns, motor activity and sleep in drug-naive rats and rats previously exposed to MDMA

A case of MAO inhibitor/MDMA interaction: agony after ecstasy

MDMA and PTSD treatment:“PTSD: from novel pathophysiology to innovative therapeutics”

Cognitive performance of MDMA-treated rhesus monkeys: sensitivity to serotonergic challenge

Immunomodulating activity of MDMA

Genetic deletion of trace amine 1 receptors reveals their role in auto-inhibiting the actions of ecstasy (MDMA)

Sex differences in the effects of MDMA (ecstasy) on plasma copeptin in healthy subjects

Effects of MDMA, MDA and MDEA on blood pressure, heart rate, locomotor activity and body temperature in the rat involve α‐adrenoceptors

Enhancement of conditioned place preference response to cocaine in rats following subchronic administration of 3, 4‐methylenedioxymethamphetamine (MDMA)

Investigation of serotonin-1A receptor function in the human psychopharmacology of MDMA

Confirmation of amphetamine, methamphetamine, MDA and MDMA in urine samples using disk solid-phase extraction and gas chromatography–mass spectrometry …

Concentrations and ratios of amphetamine, methamphetamine, MDA, MDMA, and MDEA enantiomers determined in plasma samples from clinical toxicology and …

Near-fatal hyponatraemic coma due to vasopressin over-secretion after" ecstasy"(3, 4-MDMA)

MDMA study

Fatal MDMA intoxication

Recreational use of MDMA

Prospective memory impairment in “ecstasy”(MDMA) users

Memory impairment in now abstinent MDMA users and continued users: a longitudinal follow-up

MDMA self-administration in laboratory animals: a summary of the literature and proposal for future research

Toxicity of methylenedioxymethamphetamine (MDMA) in the dog and the rat

Mechanisms of MDMA (ecstasy)-induced oxidative stress, mitochondrial dysfunction, and organ damage

Pre-exposure to (±) 3, 4-methylenedioxy-methamphetamine (MDMA) facilitates acquisition of intravenous cocaine self-administration in rats

MDMA (ecstasy) pharmacokinetics in a CYP2D6 poor metaboliser and in nine CYP2D6 extensive metabolisers

Acquisition of MDMA self‐administration: pharmacokinetic factors and MDMA‐induced serotonin release

Investigating the potential neurotoxicity of Ecstasy (MDMA): an imaging approach

Verbal working memory deficits in current and previous users of MDMA

Use of amphetamine by recreational users of ecstasy (MDMA) is associated with reduced striatal dopamine transporter densities: a β-CIT SPECT study …

Endocannabinoids and 3, 4-methylenedioxymethamphetamine (MDMA) interaction

Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans

Effects of MPEP on expression of food‐, MDMA‐or amphetamine‐conditioned place preference in rats

MDMA as a discriminative stimulus: isomeric comparisons

Behavioral and neurochemical effects of chronic methylenedioxymethamphetamine (MDMA) treatment in rhesus monkeys

Effects of (±) 3, 4-methylenedioxymethamphetamine (MDMA) on sleep and circadian rhythms

Executive function in abstinent MDMA (ecstasy') users

Serotonin release contributes to the locomotor stimulant effects of 3, 4-methylenedioxymethamphetamine in rats.

Effects of MDMA on complex brain function in laboratory animals

The ugly side of amphetamines: short-and long-term toxicity of 3, 4-methylenedioxymethamphetamine (MDMA,'Ecstasy'), methamphetamine and D-amphetamine

Sweat Testing of MDMA with the Drugwipe® Analytical Device: A Controlled Study with Two Volunteers

Is there a case for MDMA-assisted psychotherapy in the UK?

Brain serotonin function in MDMA (ecstasy) users: evidence for persisting neurotoxicity

Effects of (±) 3, 4-methylenedioxymethamphetamine (MDMA) on brain dopaminergic activity in rats

Usefulness of sweat testing for the detection of MDMA after a single-dose administration

Repeated administration of MDMA causes transient down-regulation of serotonin 5-HT2 receptors

Risperidone attenuates and reverses hyperthermia induced by 3, 4-methylenedioxymethamphetamine (MDMA) in rats

… hot on Ecstasy: physical activity and thermal comfort ratings are associated with the memory and other psychobiological problems reported by recreational MDMA …

The prosocial effects of 3, 4-methylenedioxymethamphetamine (MDMA): controlled studies in humans and laboratory animals

Carvedilol reverses hyperthermia and attenuates rhabdomyolysis induced by 3, 4-methylenedioxymethamphetamine (MDMA, Ecstasy) in an animal model

The effect of acutely administered MDMA on subjective and BOLD-fMRI responses to favourite and worst autobiographical memories

Behavioural and neurochemical comparison of chronic intermittent cathinone, mephedrone and MDMA administration to the rat

Relevance of rodent models of intravenous MDMA self-administration to human MDMA consumption patterns

Simultaneous analysis of amphetamine, methamphetamine, and 3, 4-methylenedioxymethamphetamine (MDMA) in urine samples by solid-phase extraction …

Using MDMA in psychotherapy.

… assay for enantioselective measurement of the designer drugs MDEA, MDMA, and MDA and its application to samples from a controlled study with MDMA

Neural correlates of working memory in pure and polyvalent ecstasy (MDMA) users

MDMA: interactions with other psychoactive drugs

Ecstasy: the clinical, pharmacological and neurotoxicological effects of the drug MDMA

Development and characterization of a novel animal model of intermittent MDMA (“Ecstasy”) exposure during adolescence

MDMA ('ecstasy') exhibits an anxiogenic-like activity in social encounters between male mice

Acute effects of nocturnal doses of MDMA on measures of impulsivity and psychomotor performance throughout the night

… , 4-methylenedioxyphenyl)-2-aminopropane (MDE) and N-hydroxy-1-(3, 4-methylenedioxyphenyl)-2-aminopropane (N-OH MDA) in rats trained to discriminate MDMA …

d-MDMA during vitamin E deficiency: effects on dopaminergic neurotoxicity and hepatotoxicity

3, 4-methylenedioxymethamphetamine (MDMA): current perspectives

Methysergide potentiates the hyperactivity produced by MDMA in rats

Memory performance in polyvalent MDMA (ecstasy) users who continue or discontinue MDMA use

Acute and subchronic effects of MDMA (“ecstasy”) on anxiety in male mice tested in the elevated plus-maze

Rediscovering MDMA (ecstasy): the role of the American chemist Alexander T. Shulgin

Chiral separation and quantification of R/S-amphetamine, R/S-methamphetamine, R/S-MDA, R/S-MDMA, and R/S-MDEA in whole blood by GC-EI-MS

MDMA, methamphetamine and their combination: possible lessons for party drug users from recent preclinical research

Discriminative stimulus effects of 3, 4-methylenedioxymethamphetamine (MDMA) in humans trained to discriminate among d-amphetamine, meta …

Drug use practices among MDMA/ecstasy users in Ohio: a latent class analysis

Breakthrough for trauma treatment: safety and efficacy of MDMA-assisted psychotherapy compared to paroxetine and sertraline

Investigation of MDMA-related agents in rats trained to discriminate MDMA from saline

Mortality among individuals with cannabis, cocaine, amphetamine, MDMA, and opioid use disorders: a nationwide follow-up study of Danish substance users in …

… of 3, 4-methylenedioxymethamphetamine (MDMA) enantiomers in vitro and in the MPTP-lesioned primate: R-MDMA reduces severity of dyskinesia, whereas S-MDMA …

3, 4-Methylenedioxyethylamphetamine (MDE), a novel analogue of MDMA, produces long-lasting depletion of serotonin in the rat brain

Neural and cardiac toxicities associated with 3, 4-methylenedioxymethamphetamine (MDMA)

Attenuation of 3,4‐methylenedioxymethamphetamine (MDMA, Ecstasy)‐induced rhabdomyolysis with α1‐ plus β3‐adrenoreceptor antagonists

MDMA, politics and medical research: Have we thrown the baby out with the bathwater?

Methamphetamine and MDMA (ecstasy) neurotoxicity:'of mice and men'

Action of MDMA (ecstasy) and its metabolites on arginine vasopressin release

p-Chloroamphetamine (PCA), 3,4-methylenedioxymethamphetamine (MDMA) andd-fenfluramine pretreatment attenuatesd-fenfluramine-evoked release of 5-HT in …

Is vitreous humour useful for the interpretation of 3, 4-methylenedioxymethamphetamine (MDMA) blood levels?

MDMA and fenfluramine reduce L‐DOPA‐induced dyskinesia via indirect 5‐HT1A receptor stimulation

Direct comparison of the acute subjective, emotional, autonomic, and endocrine effects of MDMA, methylphenidate, and modafinil in healthy subjects

Problematic versus non-problematic ecstasy/MDMA use: the influence of drug usage patterns and pre-existing psychiatric factors

Evidence that both intragastric and subcutaneous administration of methylenedioxymethylamphetamine (MDMA) produce serotonin neurotoxicity in rhesus monkeys

Short-and long-term effects of MDMA (“ecstasy”) on synaptosomal and vesicular uptake of neurotransmitters in vitro and ex vivo

The effect of optical isomers of 3, 4-methylenedioxymethamphetamine (MDMA) on stereotyped behavior in rats

Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex

History of MDMA

MDMA induced hyperthermia: a survivor with an initial body temperature of 42.9 degrees C.

Ecstasy (MDMA) and memory function: a meta‐analytic update

Effects of 3, 4-methylenedioxy-methamphetamine (MDMA) on anxiety in mice tested in the light-dark box

Partial lesion of the serotonergic system by a single dose of MDMA results in behavioural disinhibition and enhances acute MDMA-induced social behaviour on the …

A three-choice discrimination procedure dissociates the discriminative stimulus effects of d-amphetamine and (±)-MDMA in rats.

Neurotoxic effects of MDMA (“ecstasy”) administration to neonatal rats

Methylenedioxymethamphetamine (MDMA)-related fatalities in Australia: demographics, circumstances, toxicology and major organ pathology

Comparative effects of substituted amphetamines (PMA, MDMA, and METH) on monoamines in rat caudate: a microdialysis study

Neurobehavioral outcomes of infants exposed to MDMA (Ecstasy) and other recreational drugs during pregnancy

The effect of MDMA (“Ecstasy”) and its optical isomers on schedule-controlled responding in mice

Effects of phencyclidine, ketamine and MDMA on complex operant behavior in monkeys

Subjective ratings of prospective memory deficits in MDMA ('ecstasy') users

Effects of ecstasy (MDMA) on the brain in abstinent users: initial observations with diffusion and perfusion MR imaging

MDMA: on the translation from rodent to human dosing

Characteristics and trends of 3, 4-methylenedioxymethamphetamine (MDMA) tablets found in Taiwan from 2002 to February 2005

Post-mortem redistribution of 3, 4-methylenedioxymethamphetamine (MDMA," ecstasy") in the rabbit. Part II: post-mortem infusion in trachea or stomach.

In vivo evidence against clomethiazole being neuroprotective against MDMA ('ecstasy')-induced degeneration of rat brain 5-HT nerve terminals by a free radical …

THC prevents MDMA neurotoxicity in mice

… for drug abuse XV. Disposition of 3, 4-methylenedioxymethamphetamine (MDMA) and its related compounds into rat hair and application to hair analysis for MDMA …

Role of brain nitric oxide in (±) 3, 4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity in rats

Proton magnetic resonance spectroscopy in ecstasy (MDMA) users

DNA damage and ubiquitinated neuronal inclusions in the substantia nigra and striatum of mice following MDMA (ecstasy)

Inhibition of MAO-B protects against MDMA-induced neurotoxicity in the striatum

Behavioural and neurochemical effects of combined MDMA and THC administration in mice

MDMA-like behavioral effects of N-substituted piperazines in the mouse

MDMA produces stimulant-like conditioned locomotor activity

Ecstasy (MDMA) mimics the post-orgasmic state: impairment of sexual drive and function during acute MDMA-effects may be due to increased prolactin secretion

No evidence that MDMA-induced enhancement of emotional empathy is related to peripheral oxytocin levels or 5-HT 1a receptor activation

Involvement of inferior parietal lobules in prospective memory impairment during acute MDMA (ecstasy) intoxication: an event-related fMRI study

Multiple molecular and neuropharmacological effects of MDMA (Ecstasy)

Chronic exposure to ethanol exacerbates MDMA-induced hyperthermia and exposes liver to severe MDMA-induced toxicity in CD1 mice

Methylenedioxymethamphetamine (MDMA; Ecstasy) suppresses IL-1β and TNF-α secretion following an in vivo lipopolysaccharide challenge

Use of MDA (the" love drug") and methamphetamine in Toronto by unsuspecting users of ecstasy (MDMA)

MDMA decreases the effects of simulated social rejection

Evidence for a role of energy dysregulation in the MDMA-induced depletion of brain 5-HT

Plasma oxytocin concentrations following MDMA or intranasal oxytocin in humans

MDMA, methamphetamine, and CYP2D6 pharmacogenetics: what is clinically relevant?

Multiple MDMA (Ecstasy) overdoses at a rave event: a case series

Human pharmacology of mephedrone in comparison with MDMA

Drug intelligence based on MDMA tablets data: 2. Physical characteristics profiling

The effects of repeated administration of MDMA on the expression of sexual behavior in the male rat

Adverse symptomatology and suicide associated with the use of methylenedioxymethamphetamine (MDMA; Ecstasy)

A study of impurities in intermediates and 3, 4-methylenedioxymethamphetamine (MDMA) samples produced via reductive amination routes

Structure-activity relationships of MDMA-like substances

Integration of GC/EI-MS and GC/NCI-MS for simultaneous quantitative determination of opiates, amphetamines, MDMA, ketamine, and metabolites in human hair

MDMA and 5‐HT neurotoxicity: the empirical evidence for its adverse effects in humans–no need for translation

Adam (MDMA) and Eve (MDEA) misuse: an immunohistochemical study on three fatal cases

Acute effects of dexfenfluramine (d‐FEN) and methylenedioxymethamphetamine (MDMA) before and after short‐course, high‐dose treatment

A developmental comparison of the neurobehavioral effects of ecstasy (MDMA)

The preclinical pharmacology of mephedrone; not just MDMA by another name

Determination of MDMA, MDA, MDEA and MBDB in oral fluid using high performance liquid chromatography with native fluorescence detection

Long-term central 5-HT depletions resulting from repeated administration of MDMA enhances the effects of single administration of MDMA on schedule-controlled …

PRECLINICAL STUDY: Acquisition and reinstatement of MDMA‐induced conditioned place preference in mice pre‐treated with MDMA or cocaine during adolescence

One-year outcomes of prenatal exposure to MDMA and other recreational drugs

Enantiomer profiling of high loads of amphetamine and MDMA in communal sewage: a Dutch perspective

Deconstructing ecstasy: the politics of MDMA research

Elevation of serum prolactin and corticosterone concentrations in the rat after the administration of 3, 4-methylenedioxymethamphetamine.

Effects of cocaine and MDMA self-administration on serotonin transporter availability in monkeys

Dopaminergic mechanisms of reinstatement of MDMA‐seeking behaviour in rats

Vascular actions of MDMA involve α1 and α2‐adrenoceptors in the anaesthetized rat

Cytotoxic effects of 3,4-methylenedioxy-N-alkylamphetamines, MDMA and its analogues, on isolated rat hepatocytes

Effect of 3, 4-methylendioxymethamphetamine (MDMA,“ecstasy”) on dopamine transmission in the nucleus accumbens shell and core

Analysis of ecstasy (MDMA)‐induced transcriptional responses in the rat cortex

Behavioral profile of 3, 4-methylenedioxy-methamphetamine (MDMA) in agonistic encounters between male mice

Neural effects of MDMA as determined by functional magnetic resonance imaging and magnetic resonance spectroscopy in awake marmoset monkeys

Dantrolene in the treatment of MDMA-related hyperpyrexia: a systematic review

The N-methyl-D-aspartate (NMDA) receptor antagonist, dextrorphan, prevents the neurotoxic effects of 3, 4-methylenedioxymethamphetamine (MDMA) in rats

Inhibition of serotonin transporters disrupts the enhancement of fear memory extinction by 3, 4-methylenedioxymethamphetamine (MDMA)

High ambient temperature increases 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”)-induced Fos expression in a region-specific manner

Major depression: the relative contribution of gender, MDMA, and cannabis use

Role of 5-HT2A and 5-HT2C/B receptors in the acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on striatal single-unit activity and locomotion in freely …

Who is 'Molly'? MDMA adulterants by product name and the impact of harm-reduction services at raves

Death from hyponatraemia-induced cerebral oedema associated with MDMA (ecstasy) use

Release of serotonin induced by 3, 4-methylenedioxymethamphetamine (MDMA) and other substituted amphetamines in cultured fetal raphe neurons: further …

MDMA administration to pregnant Sprague–Dawley rats results in its passage to the fetal compartment

Potential psychiatric uses for MDMA

Medical risks associated with MDMA use.

Monoamine metabolites in the cerebrospinal fluid of recreational users of 3, 4-methylenedimethoxymethamphetamine MDMA: Ecstasy

The effects of MDMA on socio-emotional processing: Does MDMA differ from other stimulants?

Differential effect of dietary selenium on the long-term neurotoxicity induced by MDMA in mice and rats

Increases in use of novel synthetic stimulant are not directly linked to decreased use of 3, 4-methylenedioxy-N-methylamphetamine (MDMA)

Prosocial effects of MDMA: A measure of generosity

Neurotoxicity of ecstasy (MDMA): an overview

MDMA and learning: effects of acute and neurotoxic exposure in the rat

Urinary MDMA, MDA, HMMA, and HMA excretion following controlled MDMA administration to humans

Validation of an ELISA-based screening assay for the detection of amphetamine, MDMA and MDA in blood and oral fluid

Pharmacokinetics and pharmacodynamics of 3, 4-methylenedioxymethamphetamine (MDMA): interindividual differences due to polymorphisms and drug–drug …

Biochemical effects of the monoamine neurotoxins DSP‐4 and MDMA in specific brain regions of MAO‐B‐deficient mice

Differential toxic effects of methamphetamine (METH) and methylenedioxymethamphetamine (MDMA) in multidrug-resistant (mdr1a) knockout mice

Post-mortem redistribution of 3, 4-methylenedioxymethamphetamine (MDMA," ecstasy") in the rabbit

MDMA toxicity and pathological consequences: a review about experimental data and autopsy findings

Organic impurity profiling of 3, 4-methylenedioxymethamphetamine (MDMA) tablets seized in The Netherlands.

Auditory stimuli enhance MDMA-conditioned reward and MDMA-induced nucleus accumbens dopamine, serotonin and locomotor responses

Human deaths and toxic reactions attributed to MDMA and MDEA

Acute neuropsychological effects of MDMA and ethanol (co-) administration in healthy volunteers

Sex differences in the neurochemical and functional effects of MDMA in Sprague–Dawley rats

Experimental studies on 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”) and its potential to damage brain serotonin neurons

A genetic deletion of the serotonin transporter greatly enhances the reinforcing properties of MDMA in rats

Recreational ecstasy use and the neurotoxic potential of MDMA: current status of the controversy and methodological issues

Neural mechanisms of working memory in ecstasy (MDMA) users who continue or discontinue ecstasy and amphetamine use: evidence from an 18-month longitudinal …

… gas chromatographic–electron impact ionization mass spectrometric method for methylenedioxymethamphetamine (MDMA), methamphetamine and metabolites in …

Intravenous self-administration of mephedrone, methylone and MDMA in female rats

Long-term behavioral consequences of prenatal MDMA exposure

Memantine prevents MDMA-induced neurotoxicity

The nature of 3, 4-methylenedioxymethamphetamine (MDMA)-induced serotonergic dysfunction: evidence for and against the neurodegeneration hypothesis

Microglial and astroglial activation by 3, 4‐methylenedioxymethamphetamine (MDMA) in mice depends on S (+) enantiomer and is associated with an increase in …

MDMA (“Ecstasy”) suppresses the innate IFN-γ response in vivo: a critical role for the anti-inflammatory cytokine IL-10

Designer drug confusion: a focus on MDMA

Headspace sampling and detection of cocaine, MDMA, and marijuana via volatile markers in the presence of potential interferences by solid phase microextraction …

Damage of serotonergic axons and immunolocalization of Hsp27, Hsp72, and Hsp90 molecular chaperones after a single dose of MDMA administration in Dark …

NMDA receptor subunit and CaMKII changes in rat hippocampus induced by acute MDMA treatment: a mechanism for learning impairment

Neural correlates of MDMA (“Ecstasy”)-induced social interaction in rats

MDMA-assisted psychotherapy for posttraumatic stress disorder: A promising novel approach to treatment

Assessment of the MDA and MDMA optical isomers in a stimulant-hallucinogen discrimination

Differential long-term effects of MDMA on the serotoninergic system and hippocampal cell proliferation in 5-HTT knock-out vs. wild-type mice

Behavioral effects of MDMA (“Ecstasy”) on adult zebrafish

Binge ethanol administration enhances the MDMA-induced long-term 5-HT neurotoxicity in rat brain

MDMA alters emotional processing and facilitates positive social interaction

Studies of MDMA-Induced Neurotoxicity in Nonhuman Primates: A Basis for Evaluating

Cardiac oxidative stress determination and myocardial morphology after a single ecstasy (MDMA) administration in a rat model

Studies on the neuroprotective effect of pentobarbitone on MDMA-induced neurodegeneration

The rewarding properties of MDMA are preserved in mice lacking µ‐opioid receptors

The effect of catecholamine depletion by alpha-methyl-para-tyrosine on measures of cognitive performance and sleep in abstinent MDMA users

Photonic switch working in momentum-division-multiple-access (MDMA) mode for microwave and optical wavelengths based upon the measurement of the spin, the …

… human liver preparations, HepaRG, or HepG2 cell lines for metabolism studies of new psychoactive substances? A study using MDMA, MDBD, butylone, MDPPP …

Endogenous 5‐HT, released by MDMA through serotonin transporter‐and secretory vesicle‐dependent mechanisms, reduces hippocampal excitatory synaptic …

Neural correlates of the severity of cocaine, heroin, alcohol, MDMA and cannabis use in polysubstance abusers: a resting-PET brain metabolism study

Self-reported prevalence of dependence of MDMA compared to cocaine, mephedrone and ketamine among a sample of recreational poly-drug users

Sleep apnea in young abstinent recreational MDMA (“ecstasy”) consumers

New age seekers: MDMA use as an adjunct to spiritual pursuit

A reconsideration and response to Parrott AC (2013)“Human psychobiology of MDMA or 'Ecstasy': an overview of 25 years of empirical research”

Treatment with MDMA from P11–20 disrupts spatial learning and path integration learning in adolescent rats but only spatial learning in older rats

Attenuation of 3, 4-methylenedioxymethamphetamine (MDMA) induced neurotoxicity with the serotonin precursors tryptophan and 5-hydroxytryptophan

Sources of information about MDMA (3, 4-methylenedioxymethamphetamine): perceived accuracy, importance, and implications for prevention among young adult …

Acute effects of 3, 4-methylenedioxymethamphetamine (MDMA) on 5-HT cell firing and release: comparison between dorsal and median raphe 5-HT systems

Role of α2A‐adrenoceptors in the effects of MDMA on body temperature in the mouse

Blockade of 5-HT 2 receptor selectively prevents MDMA-induced verbal memory impairment

Are there sex differences associated with the effects of ecstasy/3, 4-methylenedioxymethamphetamine (MDMA)?

Studies on the role of dopamine D1 receptors in the development and expression of MDMA-induced behavioral sensitization in rats

Progress and promise for the MDMA drug development program

Acute administration of 3, 4-methylenedioxymethamphetamine (MDMA) induces oxidative stress, lipoperoxidation and TNFα-mediated apoptosis in rat liver

Reinstatement of MDMA (ecstasy) seeking by exposure to discrete drug-conditioned cues

Candyflipping': synergistic discriminative effect of LSD and MDMA

Effects of priming injections of MDMA and cocaine on reinstatement of MDMA-and cocaine-seeking in rats

The influence of genetic and environmental factors among MDMA users in cognitive performance

Acute behavioural and neurotoxic effects of MDMA plus cocaine in adolescent mice

MPTP‐induced dopamine neuron degeneration and glia activation is potentiated in MDMA‐pretreated mice

MDMA and methamphetamine: some paradoxical negative and positive mood changes in an acute dose laboratory study

An antisense oligonucleotide targeted at MAO-B attenuates rat striatal serotonergic neurotoxicity induced by MDMA

Party people: Personality and MDMA use of house party visitors

Methylenedioxymethamphetamine (MDMA,“ecstasy”)

Plasma levels of parent compound and metabolites after doses of either d-fenfluramine or d-3, 4-methylenedioxymethamphetamine (MDMA) that produce long-term …

Use of MDMA and other illicit drugs by young adult males in Northern Spain

Hair MDMA samples are consistent with reported ecstasy use: findings from a study investigating effects of ecstasy on mood and memory

MDMA effects in brain: pharmacologic profile and evidence of neurotoxicity from neurochemical and autoradiographic studies

Stereochemistry of the metabolism of MDMA to MDA

Acute concomitant effects of MDMA binge dosing on extracellular 5-HT, locomotion and body temperature and the long-term effect on novel object discrimination in …

'Ecstasy'as a social drug: MDMA preferentially affects responses to emotional stimuli with social content

Aortic dissection after ingestion of" ecstasy"(MDMA)

Ecstasy (MDMA) and oral health

Qualitative review of serotonin syndrome, ecstasy (MDMA) and the use of other serotonergic substances: hierarchy of risk

Cardiovascular autonomic dysregulation in users of MDMA (“ecstasy”)

Differential effects of MDMA and scopolamine on working versus reference memory in the radial arm maze task

Brain serotonin transporter binding in former users of MDMA ('ecstasy')

Fatality due to combined use of the designer drugs MDMA and PMA: a distribution study

Comparison of the discriminative stimulus effects of 3, 4-methylenedioxymethamphetamine (MDMA) and cocaine: asymmetric generalization

Assessing long-term effects of MDMA (Ecstasy).

High-pressure liquid chromatography/electrochemical detection method for monitoring MDA and MDMA in whole blood and other biological tissues

MDMA effects consistent across laboratories

MDMA and seizures: a dangerous liaison?

… (MDMA) on serotonin transporter and vesicular monoamine transporter 2 protein and gene expression in rats: implications for MDMA neurotoxicity

Ecstasy/MDMA and cannabis: the complexities of their interactive neuropsychobiological effects

A prospective study of learning, memory, and executive function in new MDMA users

Calpain and caspase proteolytic markers co-localize with rat cortical neurons after exposure to methamphetamine and MDMA

Ecstasy (MDMA), amphetamine, and LSD: Comparative mood profiles in recreational polydrug users

Drug seeking in response to a priming injection of MDMA in rats: relationship to initial sensitivity to self-administered MDMA and dorsal striatal dopamine

MDMA-induced c-Fos expression in oxytocin-containing neurons is blocked by pretreatment with the 5-HT-1A receptor antagonist WAY 100635

α1-Adrenergic receptors mediate the locomotor response to systemic administration of (±)-3, 4-methylenedioxymethamphetamine (MDMA) in rats

Metabolites of MDMA induce oxidative stress and contractile dysfunction in adult rat left ventricular myocytes

Fluoxetine pretreatment effects pharmacokinetics of 3, 4‐methylenedioxymethamphetamine (MDMA, ECSTASY) in rat

A study on the mechanisms by which minocycline protects against MDMA ('ecstasy')-induced neurotoxicity of 5-HT cortical neurons

MDMA in Adolescent Male Rats: Decreased Serotonin in the Amygdala and Behavioral Effects in the Elevated Plus‐Maze Test

MDMA and fenfluramine alter the response of the circadian clock to a serotonin agonist in vitro

Protection against MDMA-induced dopaminergic neurotoxicity in mice by methyllycaconitine: involvement of nicotinic receptors

Differential response of nNOS knockout mice to MDMA (“ecstasy”)‐and methamphetamine‐induced psychomotor sensitization and neurotoxicity

Chronic exposure to MDMA (Ecstasy) elicits behavioral sensitization in rats but fails to induce cross-sensitization to other psychostimulants

Study on the neuroprotective effect of fluoxetine against MDMA-induced neurotoxicity on the serotonin transporter in rat brain using micro-PET

… –nonenzymatic cellular antioxidant defense systems response and immunohistochemical detection of MDMA, VMAT2, HSP70, and apoptosis as biomarkers for MDMA …

Enantiomeric Separation and Quantitation of (±)-Amphetamine,(±)-Methamphetamine,(±)-MDA,(±)-MDMA, and (±)-MDEA in Urine Specimens by GC-EI-MS after …

Determination of MDMA, MDEA and MDA in urine by high performance liquid chromatography with fluorescence detection

… and spectroscopic characterisation of amphetamine-like drugs: application to the screening of 3, 4-methylenedioxymethamphetamine (MDMA) and its synthetic …

(±) 3, 4-Methylenedioxymethamphetamine (MDMA) produces long-term reductions in brain 5-hydroxytryptamine in rats

Involvement of D1 dopamine receptor in MDMA-induced locomotor activity and striatal gene expression in mice

A pure amnestic syndrome after MDMA (" ecstasy") ingestion.

MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase

Critical role of peripheral vasoconstriction in fatal brain hyperthermia induced by MDMA (Ecstasy) under conditions that mimic human drug use

Neurotoxicity and persistent cognitive deficits induced by combined MDMA and alcohol exposure in adolescent rats

Chronic treatment with supraphysiological levels of corticosterone enhances D-MDMA-induced dopaminergic neurotoxicity in the C57BL/6J female mouse

MDMA and memory: the acute and chronic effects of MDMA in pigeons performing under a delayed-matching-to-sample procedure

Self-reported ecstasy/MDMA/“Molly” use in a sample of nightclub and dance festival attendees in New York City

Repeated adolescent 3, 4-methylenedioxymethamphetamine (MDMA) exposure in rats attenuates the effects of a subsequent challenge with MDMA or a 5 …

MDMA “ecstasy” alters hyperactive and perseverative behaviors in dopamine transporter knockout mice

Association of caffeine to MDMA does not increase antinociception but potentiates adverse effects of this recreational drug

MDMA and MDA concentrations in antemortem and postmortem specimens in fatalities following hospital admission

Elemental analysis of 3, 4-methylenedioxymethamphetamine (MDMA): A tool to determine the synthesis method and trace links

Glucocorticoids and 3, 4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity

Prospective associations between meth/amphetamine (speed) and MDMA (ecstasy) use and depressive symptoms in secondary school students

MDMA on the street: Analysis Anonymous®

Sub-chronic nandrolone treatment modifies neurochemical and behavioral effects of amphetamine and 3, 4-methylenedioxymethamphetamine (MDMA) in rats

Forensic electrochemistry: simultaneous voltammetric detection of MDMA and its fatal counterpart “Dr Death”(PMA)

Different likelihood ratio approaches to evaluate the strength of evidence of MDMA tablet comparisons

Evidence that MDMA ('ecstasy') increases cannabinoid CB2 receptor expression in microglial cells: role in the neuroinflammatory response in rat brain

The origin of MDMA ('ecstasy')–separating the facts from the myth

… of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: similarities to 3, 4-(methylenedioxy) methamphetamine (MDMA)

Sensitive gas chromatography-mass spectrometry method for simultaneous measurement of MDEA, MDMA, and metabolites HMA, MDA, and HMMA in human urine

Structure-activity relationships of MDMA and related compounds: A new class of psychoactive agents?

Mephedrone does not damage dopamine nerve endings of the striatum, but enhances the neurotoxicity of methamphetamine, amphetamine, and MDMA

MDMA exposure alters cognitive and electrophysiological sensitivity to rapid tryptophan depletion in rhesus monkeys

Application of the Syva EMIT and Abbott TDx amphetamine immunoassays to the detection of 3, 4-methylenedioxymethamphetamine (MDMA) and 3, 4 …

Single dose of MDMA causes extensive decrement of serotoninergic fibre density without blockage of the fast axonal transport in Dark Agouti rat brain and spinal cord

… of (±) 3, 4-methylenedioxymethamphetamine (MDMA,“Ecstasy”) and its major metabolites in squirrel monkeys at plasma concentrations of MDMA that develop after …

Effects of the endogenous PPAR‐α agonist, oleoylethanolamide on MDMA‐induced cognitive deficits in mice

Determination of synthesis route of 1-(3, 4-methylenedioxyphenyl)-2-propanone (MDP-2-P) based on impurity profiles of MDMA

Effect of the CB1 cannabinoid agonist WIN 55212-2 on the acquisition and reinstatement of MDMA-induced conditioned place preference in mice

Ecstasy (MDMA): effects and patterns of use reported by users in Sao Paulo

Serotonergic modulation of 3, 4-methylenedioxymethamphetamine (MDMA)-elicited reduction of response rate but not rewarding threshold in accumbal self …

Adolescent pre‐exposure to ethanol and 3, 4‐methylenedioxymethylamphetamine (MDMA) increases conditioned rewarding effects of MDMA and drug‐induced …

The effect of MDA and MDMA (“Ecstasy”) isomers in combination with pirenpirone on operant responding in mice

MDMA/Ecstasy use among young people in Ohio: Perceived risk and barriers to intervention

Ethanol increases the distribution of MDMA to the rat brain: possible implications in the ethanol-induced potentiation of the psychostimulant effects of MDMA

PRECLINICAL STUDY: Changes in leptin, ghrelin, growth hormone and neuropeptide‐Y after an acute model of MDMA and methamphetamine exposure in rats

… of 3, 4‐Methylenedioxyethamphetamine (MDEA,“Eve”) on Body Temperature and Long Term Degeneration of 5‐HT Neurones in Brain: A Comparison with MDMA (“ …

3, 4-Methylenedioxymethamphetamine (" ecstasy") selectively destroys brain serotonin terminals in rhesus monkeys.

MDMA‐evoked changes in raclopride and NMSP binding in living pig brain

Adolescent pre-exposure to ethanol or MDMA prolongs the conditioned rewarding effects of MDMA

… sensitive semi-micro column HPLC method with peroxyoxalate chemiluminescence detection and column switching for determination of MDMA-related compounds in …

On the anxiogenic and anxiolytic nature of long-term cerebral 5-HT depletion following MDMA.

Hallucinogenic and stimulatory amphetamine derivatives: fingerprinting DOM, DOI, DOB, MDMA, and MBDB by spectral analysis of brain field potentials in the freely …

Effects of alcohol (BAC 0.5‰) and ecstasy (MDMA 100 mg) on simulated driving performance and traffic safety

Microdialysis studies on 3, 4-methylenedioxymethamphetamine-induced dopamine release: effect of dopamine uptake inhibitors.

Can MDMA play a role in the treatment of substance abuse?

Human pharmacology of 3, 4-methylenedioxymethamphetamine (MDMA, ecstasy) after repeated doses taken 2 h apart

3, 4-methylenedioxymethamphetamine (MDMA, ecstasy)-mediated production of hydrogen peroxide in an in vitro model: the role of dopamine, the serotonin-reuptake …

Attenuation of alcohol consumption by MDMA (ecstasy) in two strains of alcohol-preferring rats

Fatal MDMA intoxication

Interactions between ethanol and cocaine, amphetamine, or MDMA in the rat: thermoregulatory and locomotor effects

Development and validation of a disk solid phase extraction and gas chromatography–mass spectrometry method for MDMA, MDA, HMMA, HMA, MDEA …

Validity of β‐CIT SPECT in detecting MDMA‐induced serotonergic neurotoxicity

Context‐dependent behavioural and neuronal sensitization in striatum to MDMA (ecstasy) administration in rats

Event-related potentials (ERPs) in ecstasy (MDMA) users during a visual oddball task

Morbidity associated with MDMA (ecstasy) abuse: a survey of emergency department admissions

MDMA alters the response of the circadian clock to a photic and non-photic stimulus

Neuroimaging in human MDMA (Ecstasy) users: A cortical model

Ecstasy (MDMA), methamphetamine, and date rape (drug-facilitated sexual assault): a consideration of the issues

… of prelimbic and infralimbic medial prefrontal cortex in discrete cue-induced reinstatement of 3, 4-methylenedioxymethamphetamine (MDMA; ecstasy) seeking in rats

Sprague–Dawley rats display metabolism-mediated sex differences in the acute toxicity of 3, 4-methylenedioxymethamphetamine (MDMA, ecstasy)

Co-administration of THC and MDMA ('ecstasy') synergistically disrupts memory in rats

Initial deficit and recovery of function after MDMA preexposure in rats

Methylenedioxymethamphetamine (MDMA;'Ecstasy') suppresses antigen specific IgG2a and IFN-γ production

Role of endogenous dopamine in the central serotonergic deficits induced by 3, 4-methylenedioxymethamphetamine.

The detection of novel stimulants in oral fluid from users reporting ecstasy, Molly and MDMA ingestion

Inappropriate antidiuretic hormone secretion and extreme rises in serum creatinine kinase following MDMA ingestion.

The effects of 3, 4-methylenedioxymethamphetamine (MDMA) on nicotinic receptors: intracellular calcium increase, calpain/caspase 3 activation, and functional …

The effects of MDMA pretreatment on the behavioural effects of other drugs of abuse in the rat elevated plus-maze test

Repeated exposure to MDMA provides neuroprotection against subsequent MDMA-induced serotonin depletion in brain

Executive working memory deficits in abstinent ecstasy/MDMA users: a critical review

MDMA (ecstacy): Useful information for health professionals involved in drug education programs

Contribution of impulsivity and novelty‐seeking to the acquisition and maintenance of MDMA self‐administration

Effects of acute 3, 4-methylenedioxymethamphetamine on sleep and daytime sleepiness in MDMA users: a preliminary study

Basic and neutral route specific impurities in MDMA prepared by different synthesis methods: comparison of impurity profiles

Direct screening of urine for MDMA and MDA by liquid chromatography-tandem mass spectrometry

MDMA (ecstasy)

Cocaine, metamfetamine, and MDMA abuse: the role and clinical importance of neuroadaptation

… –mass spectrometry assay for enantioselective measurement of amphetamines in oral fluid: application to a controlled study with MDMA and driving under the …

Users' perceptions of the risks and effects of taking ecstasy (MDMA): a questionnaire study

Discriminative stimulus effects of psychostimulants and hallucinogens in S (+)-3, 4-methylenedioxymethamphetamine (MDMA) and R (−)-MDMA trained mice

Disposition of MDMA and metabolites in human sweat following controlled MDMA administration

Hyperthermic and neurotoxic effect of 3, 4-methylenedioxymethamphetamine (MDMA) in guinea pigs

MDMA administration during adolescence exacerbates MPTP-induced cognitive impairment and neuroinflammation in the hippocampus and prefrontal cortex

Bilateral sixth nerve palsy associated with MDMA (“ecstasy”) abuse

MDMA (“ecstasy”) abuse as an example of dopamine neuroplasticity

Mental disorders in current and former heavy ecstasy (MDMA) users

Repeated intermittent MDMA binges reduce DAT density in mice and SERT density in rats in reward regions of the adolescent brain

The role of 5-HT in the impairment of thermoregulation observed in rats administered MDMA ('ecstasy') when housed at high ambient temperature

Relation of sex and estrous phase to deficits in prepulse inhibition of the startle response induced by ecstasy (MDMA)

Neuroimaging of chronic MDMA (“ecstasy”) effects: A meta-analysis

Synthesis, in vitro formation, and behavioural effects of glutathione regioisomers of alpha-methyldopamine with relevance to MDA and MDMA (ecstasy)

Characterization of the Translocation of Protein Kinase C (PKC) by 3, 4-methylenedioxymethamphetamine (MDMA/Ecstasy) in Synaptosomes:: Evidence for a …

MDMA induces caspase‐3 activation in the limbic system but not in striatum

The profiling of MDMA tablets: a study of the combination of physical characteristics and organic impurities as sources of information

The variety of ecstasy/MDMA users: results from the National Epidemiologic Survey on alcohol and related conditions

Why MDMA therapy for alcohol use disorder? And why now?

Current perspective on MDMA-assisted psychotherapy for posttraumatic stress disorder

The acute and sub-acute effects of 'ecstasy'(MDMA) on processing of facial expressions: preliminary findings

Chronic paranoid psychosis after misuse of MDMA.

Evidence for executive deficits among users of MDMA (Ecstasy)

EMIT-dau monoclonal amphetamine/methamphetamine assay. II. Detection of methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA)

Activation of protein kinase C (PKC) by 3, 4-methylenedioxymethamphetamine (MDMA) occurs through the stimulation of serotonin receptors and transporter

… mapping shows that serotonin rather than dopamine receptor mRNA expressions are affected after repeated intermittent administration of MDMA in rat brain

MDMA assisted psychotherapy found to have a large effect for chronic post-traumatic stress disorder

Memory impairment and hippocampus specific protein oxidation induced by ethanol intake and 3, 4‐Methylenedioxymethamphetamine (MDMA) in mice

Efficacy of 3, 4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for posttraumatic stress disorder: A systematic review and meta-analysis

Intracranial self-administration of MDMA into the ventral striatum of the rat: differential roles of the nucleus accumbens shell, core, and olfactory tubercle

Effect of a serotonin depleting regimen of 3, 4-methylenedioxymethamphetamine (MDMA) on the subsequent stimulation of acetylcholine release in the rat prefrontal …

Caffeine induces a profound and persistent tachycardia in response to MDMA (“Ecstasy”) administration

Role of the dopaminergic system in the acquisition, expression and reinstatement of MDMA-induced conditioned place preference in adolescent mice

Mechanisms mediating the ability of caffeine to influence MDMA ('Ecstasy')‐induced hyperthermia in rats

MDMA produces a delayed and sustained increase in the extracellular concentration of glutamate in the rat hippocampus

Neuroendocrine abnormalities in recreational ecstasy (MDMA) users: is it ecstasy or cannabis?

MDMA stimulus generalization to the 5-HT1A serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin

Neurocognitive impairments in MDMA and other drug users: MDMA alone may not be a cognitive risk factor

Syllogistic reasoning performance in MDMA (Ecstasy) users.

“You Can't Just Give Your Best Mate a Massive Hug Every Day” Young Men, Play and MDMA

Long-term effects of repeated social stress on the conditioned place preference induced by MDMA in mice

Modification of Ag nanoparticles with mixed thiols for improved SERS detection of poorly adsorbing target molecules: detection of MDMA

MDMA: fact and fallacy, and the need to increase knowledge in both the scientific and popular press

Pharmacological aspects of the combined use of 3, 4‐methylenedioxymethamphetamine (MDMA, ecstasy) and gamma‐hydroxybutyric acid (GHB): a review of the …

Comparative potencies of 3,4‐methylenedioxymethamphetamine (MDMA) analogues as inhibitors of noradrenaline and 5‐HT transport in mammalian cell …

Sex‐dependent long‐term effects of adolescent exposure to THC and/or MDMA on neuroinflammation and serotoninergic and cannabinoid systems in rats

Ecstasy (MDMA)-addicted subjects show increased serum levels of brain-derived neurotrophic factor, independently from a rise of drug-induced psychotic symptoms.

Effects of 3, 4-methylenedioxymethamphetamine (MDMA,'Ecstasy') and para-methoxyamphetamine on striatal 5-HT when co-administered with moclobemide

Tracing the “event” of drug use:“Context” and the coproduction of a night out on MDMA

Prospective memory impairment in abstinent MDMA (" Ecstasy") users

Clandestine manufacture of 3, 4-methylenedioxymethylamphetamine (MDMA) by low pressure reductive amination. A mass spectrometric study of some reaction …

MDMA and parkinsonism

Acute effects of methylenedioxymethamphetamine (MDMA) on several complex brain functions in monkeys

The solid-state terahertz spectrum of MDMA (Ecstasy)–A unique test for molecular modeling assignments

Depression, impulsiveness, sleep, and memory in past and present polydrug users of 3, 4-methylenedioxymethamphetamine (MDMA, ecstasy)

Ecstasy (MDMA) and high prevalence psychiatric symptomatology: somatic anxiety symptoms are associated with polydrug, not ecstasy, use

MDMA-Like Stimulus Effects of Hallucinogens in Male Fawn–Hooded Rats

… –MS metabolomics reveals disturbed metabolic pathways in primary mouse hepatocytes exposed to subtoxic levels of 3, 4-methylenedioxymethamphetamine (MDMA)

Increased cortisol levels in hair of recent Ecstasy/MDMA users

An appraisal of the pharmacological and toxicological effects of a single oral administration of 3, 4‐methylenedioxymethamphetamine (MDMA) in the rat

Behavioral and neurochemical consequences of multiple MDMA administrations in the rat: role of individual differences in anxiety-related behavior

Visuo‐spatial working memory deficits in current and former users of MDMA ('ecstasy')

Acute psychomotor, memory and subjective effects of MDMA and THC co-administration over time in healthy volunteers

3 cases of primary intracranial hemorrhage associated with “Molly”, a purified form of 3, 4-methylenedioxymethamphetamine (MDMA)

Examining the role of oxytocin in the interoceptive effects of 3, 4‐methylenedioxymethamphetamine (MDMA,'ecstasy') using a drug discrimination paradigm in the rat

Imaging brain activity in conscious monkeys following oral MDMA (“ecstasy”)

Rhabdomyolysis in MDMA intoxication: a rapid and underestimated killer.“Clean” ecstasy, a safe party drug?

3, 4-methylenedioxymethamphetamine (MDMA) intoxication in an infant chronically exposed to cocaine

Synergistic toxicity of ethanol and MDMA towards primary cultured rat hepatocytes

Effects of salicylate on 3, 4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity in rats

MDMA powder, pills and crystal: the persistence of ecstasy and the poverty of policy

Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA

Serotonin neurotoxicity in rats after combined treatment with a dopaminergic agent followed by a nonneurotoxic 3, 4-methylenedioxymethamphetamine (MDMA) …

50-kHz calls in rats: Effects of MDMA and the 5-HT1A receptor agonist 8-OH-DPAT

Nonlinear pharmacokinetics of (±) 3, 4-methylenedioxymethamphetamine (MDMA) and its pharmacodynamic consequences in the rat

The intriguing effects of ecstasy (MDMA) on cognitive function in mice subjected to a minimal traumatic brain injury (mTBI)

Cerebral oedema after MDMA (" ecstasy") and unrestricted water intake. Hyponatraemia must be treated with low water input.

… method for simultaneous analysis of 10 amphetamine-, methamphetamine-and 3, 4-methylenedioxymethamphetamine-related (MDMA) analytes in human meconium

Chronic ecstasy (MDMA) use is associated with deficits in task-switching but not inhibition or memory updating executive functions

Serotonergic deficits and impaired passive-avoidance learning in rats by MDEA: a comparison with MDMA

Use of dynamically coated capillaries for the routine analysis of methamphetamine, amphetamine, MDA, MDMA, MDEA, and cocaine using capillary electrophoresis

Synthesis and cyclic voltammetry studies of 3, 4-methylenedioxymethamphetamine (MDMA) human metabolites

Intermittent ethanol exposure increases long-lasting behavioral and neurochemical effects of MDMA in adolescent mice

Serotonin 5-HT4 receptors in the nucleus accumbens are specifically involved in the appetite suppressant and not locomotor stimulant effects of MDMA ('ecstasy')

The A2a adenosine receptor modulates the reinforcement efficacy and neurotoxicity of MDMA

MDMA (ecstasy) effects in pubescent rats: males are more sensitive than females

Pharmacogenetic studies of change in cortisol on ecstasy (MDMA) consumption

Effects of fenfluramine, m-CPP and triazolam on repeated-acquisition in squirrel monkeys before and after neurotoxic MDMA administration

Conditioning following repeated exposure to MDMA in rats: Role in the maintenance of MDMA self-administration.

'Is MDMA a human neurotoxin?': diverse views from the discussants

A Cannabinoid CB 1 Receptor Antagonist Ameliorates Impairment of Recognition Memory on Withdrawal from MDMA (Ecstasy)

Intravenous methamphetamine self-administration in rats: effects of intravenous or intraperitoneal MDMA co-administration

Modulation of methylenedioxymethamphetamine-induced striatal dopamine release by the interaction between serotonin and gamma-aminobutyric acid in the …

MDMA (“ecstasy”) impairs learning in the Morris Water Maze and reduces hippocampal LTP in young rats

Ecstasy (MDMA) exposure and neuropsychological functioning: a polydrug perspective

Direct determination of glucuronide and sulfate of 4-hydroxy-3-methoxymethamphetamine, the main metabolite of MDMA, in human urine

Optimization of extraction parameters for the chemical profiling of 3, 4-methylenedioxymethamphetamine (MDMA) tablets

Methods for the Analysis of 1-(3,4-Methylenedioxyphenyl)-2-Butanamine and N-Methy 1-(3,4-Methylenedioxyphenyl)- 2-Propanamine (MDMA)

Deaths involving MDMA and the concomitant use of pharmaceutical drugs

Acute psychomotor effects of MDMA and ethanol (co-) administration over time in healthy volunteers

Involvement of NMDA glutamate receptors in the acquisition and reinstatement of the conditioned place preference induced by MDMA

MDMA modifies active avoidance learning and recall in mice

Locomotor and pyretic effects of MDMA–ethanol associations in rats

MDMA pretreatment leads to mild chronic unpredictable stress-induced impairments in spatial learning.

Acute liver failure following the use of ecstasy (MDMA)

Time course analysis of the discriminative stimulus effects of the optical isomers of 3, 4-methylenedioxymethamphetamine (MDMA)

Hallucinogen persisting perception disorder and the serotonergic system: a comprehensive review including new MDMA-related clinical cases

Reinforcing effects of methylenedioxy amphetamine congeners in rhesus monkeys: are intravenous self-administration experiments relevant to MDMA …

The prevalence of MDMA/MDA in both hair and urine in drug users

Verbal memory deficits are correlated with prefrontal hypometabolism in 18 FDG PET of recreational MDMA users

Prior MDMA (Ecstasy) use is associated with increased basal ganglia–thalamocortical circuit activation during motor task performance in humans: An fMRI study

Central serous chorioretinopathy in a patient using methylenedioxymethamphetamine (MDMA) or “ecstasy”

Acute and carryover effects in mice of MDMA (“ecstasy”) administration during periadolescence

Occipital cortical proton MRS at 4 Tesla in human moderate MDMA polydrug users

The role of adenosine A1 and A2A receptors in the caffeine effect on MDMA-induced DA and 5-HT release in the mouse striatum

“Ecstasy” to addiction: Mechanisms and reinforcing effects of three synthetic cathinone analogs of MDMA

The impact of experimental design on assessing mechanism-based inactivation of CYP2D6 by MDMA (Ecstasy)

Second thoughts on 3, 4-methylenedioxymethamphetamine (MDMA) neurotoxicity

Effects of 3, 4‐methylenedioxymethamphetamine (MDMA) and its main metabolites on cardiovascular function in conscious rats

Attenuation of the disruptive effects of (+/-) 3, 4-methylene dioxymethamphetamine (MDMA) on delayed matching-to-sample performance in the rat.

Chronic stress enhances the corticosterone response and neurotoxicity to+ 3, 4-methylenedioxymethamphetamine (MDMA): the role of ambient temperature

Patterns of memory dysfunction in current and 2-year abstinent MDMA users

Oxytocin receptor gene variation predicts subjective responses to MDMA

Depressive symptomatology in young adults with a history of MDMA use: a longitudinal analysis

Receptor pharmacology of MDMA and related hallucinogens.

3, 4-Methylenedioxymethamphetamine (MDMA) and other amphetamine derivatives

3, 4-Methylenedioxymethamphetamine and 3, 4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by …

A fatal case of myocardial damage due to misuse of the “designer drug” MDMA

Restraint as a stressor in mice:: Against the dopaminergic neurotoxicity of d-mdma, low body weight mitigates restraint-induced hypothermia and consequent …

Two-dimensional gas chromatography/electron-impact mass spectrometry with cryofocusing for simultaneous quantification of MDMA, MDA, HMMA, HMA, and MDEA …

The scheduling of MDMA: A pharmacist's perspective

The public health implications of MDMA use

Behavioural and neurotoxic long-lasting effects of MDMA plus cocaine in adolescent mice

Increased oxidative‐modifications of cytosolic proteins in 3, 4‐methylenedioxymethamphetamine (MDMA, ecstasy)‐exposed rat liver

Inhibitory effects of dopamine and methylenedioxymethamphetamine (MDMA) on glutamate-evoked firing of nucleus accumbens and caudate/putamen cells are …

GENETIC STUDY: 5‐HTTLPR polymorphism, mood disorders and MDMA use in a 3‐year follow‐up study

Mice with decreased cerebral dopamine function following a neurotoxic dose of MDMA (3, 4-methylenedioxymethamphetamine,“Ecstasy”) exhibit increased ethanol …

MDMA-induced impairment in primates: antagonism by a selective norepinephrine or serotonin, but not by a dopamine/norepinephrine transport inhibitor

3, 4‐methylenedioxymethamphetamine (MDMA; Ecstasy) administration produces dose‐dependent neurochemical, endocrine and immune changes in the rat

… effects of 3, 4-methylenedioxypyrovalerone (MDPV) and 4-methylmethcathinone (mephedrone) in rats trained to discriminate MDMA or a d-amphetamine+ MDMA …

Epidemiology of MDMA and associated club drugs in the Seattle area

Age-dependent (+) MDMA-mediated neurotoxicity in mice

A PET study of effects of chronic 3, 4‐methylenedioxymethamphetamine (MDMA,“ecstasy”) on serotonin markers in Göttingen minipig brain

Repeated exposure to methylenedioxymethamphetamine (MDMA) alters nucleus accumbens neuronal responses to dopamine and serotonin

Distribution of methylenedioxymethamphetamine (MDMA) and methylenedioxyamphetamine (MDA) in postmortem and antemortem specimens

Dose-related effects of MDMA on psychomotor function and mood before, during, and after a night of sleep loss

Toxicity and deaths from 3, 4-methylenedioxymethamphetamine (" ecstasy")

Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine.

Methamphetamine and methylenedioxymethamphetamine neurotoxicity: possible mechanisms of cell destruction

Methamphetamine neurotoxicity and striatal glutamate release: comparison to 3, 4-methylenedioxymethamphetamine

Subjective effects of 3, 4-methylenedioxymethamphetamine in recreational users

(±3, 4-Methylenedioxymethamphetamine Selectively Damages Central Serotonergic Neurons in Nonhuman Primates

(±) 3, 4-Methylenedioxymethamphetamine ('Ecstasy')-induced serotonin neurotoxicity: studies in animals

Oxidation of methamphetamine and methylenedioxymethamphetamine by CYP2D6

Neurotoxicity of methamphetamine and 3, 4-methylenedioxymethamphetamine

Different glial response to methamphetamine-and methylenedioxymethamphetamine-induced neurotoxicity

In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain

Depression of rat brain tryptophan hydroxylase activity following the acute administration of methylenedioxymethamphetamine

Rapid and transient inhibition of mitochondrial function following methamphetamine or 3, 4-methylenedioxymethamphetamine administration

A comparison of the physiological, behavioral, neurochemical and microglial effects of methamphetamine and 3, 4-methylenedioxymethamphetamine in the mouse

Methylenedioxymethamphetamine: a potentially neurotoxic amphetamine analogue

The demethylenation of methylenedioxymethamphetamine (“ecstasy”) by debrisoquine hydroxylase (CYP2D6)

Metabolism of methylenedioxymethamphetamine: formation of dihydroxymethamphetamine and a quinone identified as its glutathione adduct.

Antagonism of the neurotoxicity due to a single administration of methylenedioxymethamphetamine

Lasting neuropsychiatric sequelae of (+-) methylenedioxymethamphetamine ('ecstasy') in recreational users.

Is ecstasy an “empathogen”? Effects of±3, 4-methylenedioxymethamphetamine on prosocial feelings and identification of emotional states in others

Potentiation of 3, 4-methylenedioxymethamphetamine-induced dopamine release and serotonin neurotoxicity by 5-HT2 receptor agonists

Tissue distribution of methylenedioxymethamphetamine

MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study

Effects of Hallucinogens and Other Drugs on Mood and Performance

Stanford Regulating Circuits of the Brain Study - MDMA

MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function

The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD.

Bristol Imperial MDMA in Alcoholism Study

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-2)

Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD (Canada)

A Multi-Site Study of MDMA-Assisted Psychotherapy for Eating Disorders

Effect of Methylenedioxymethamphetamine (MDMA) (Serotonin Release) on Fear Extinction

Evaluation of MDMA on Startle Response

Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD

Effects of MDMA on Emotional and Social Memories

MDMA-Assisted Psychotherapy in Veterans With Combat-Related, Refractory PTSD

-Methylenedioxymethamphetamine (MDMA, Ecstasy) Induced Changes in Drug Metabolism: Gender and Genetic Polymorphisms

Exploring Mechanisms of Action in MDMA-assisted Psychotherapy for PTSD

Influence of Bupropion on the Effects of MDMA

Study of the Effects of MDMA/Ecstasy on Water Regulation, Sleep, and Cognition.

Phase 2 Pilot Safety Study of MDMA-assisted Therapy for Social Anxiety in Autistic Adults

Pharmacological Interaction Between Carvedilol and Methylenedioxymethamphetamine (MDMA)

Pharmacological Interaction Between Clonidine and Methylenedioxymethamphetamine (MDMA)

Effects of MDMA on Social and Emotional Processing

MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD

Pharmacological Interaction Between Pindolol and MDMA (3,4-Methylenedioxymethamphetamine)

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1)

Role of Serotonin in Acute and Subacute MDMA Effects

Interaction Between Duloxetine and 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy)

MDMA-Assisted Psychotherapy for Anxiety Associated With a Life-Threatening Illness

A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD

Emotional Effects of Methylphenidate and MDMA in Healthy Subjects

Pharmacological Interaction Between Doxazosin and Methylenedioxymethamphetamine (MDMA)

Effects of MDMA and Methylphenidate on Social Cognition

Study Comparing Three Doses of MDMA Along With Therapy in Veterans With Posttraumatic Stress Disorder

Neurobiology and Pharmacokinets of Acute MDMA Administration

Additional MDMA-assisted Therapy for People Who Relapsed After MDMA-assisted Therapy Trial

Interaction Between Reboxetine and 3,4-Methylenedioxymethamphetamine: Pharmacodynamics (PD) and Pharmacokinetics (PK)

Randomized, Double-blind, Controlled of MDMA-assisted Psychotherapy in 12 Subjects With PTSD

Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI Study

Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers

Dose-Response Study of MDMA-assisted Psychotherapy in People With PTSD

A Multi-site Expanded Access Program for MDMA-assisted Psychotherapy for Patients With Treatment-resistant PTSD

Study of 3,4-Methylenedioxymethamphetamine-assisted Psychotherapy in People With Posttraumatic Stress Disorder

Randomized, Double-blind, Active Placebo-Controlled Pilot Study of MDMA-assisted Psychotherapy in People With Chronic PTSD

Effects of Drugs on Responses to Brain and Emotional Processes

Naturalistic Study Into the Hangover Effects of MDMA

Randomized Placebo-controlled Study of MDMA-assisted Therapy in People With PTSD - Israel

MDMA-Assisted Psychotherapy in People With Posttraumatic Stress Disorder

MDMA-assisted Therapy in People With Anxiety Related to Advanced Stage Cancer

Effect of Stimulant Drugs on Social Perception

Abuse Liability and Human Pharmacology of Mephedrone

The NeXT Study; The Netherlands XTC Toxicity Study

Role of Dopamine, Serotonin and 5-HT2A Receptors in Emotion Processing

Characterization of the Prosocial and Prosexual Effects of GHB

Mood Effects of Serotonin Agonists

Effects of MDMA Co-administration on the Response to LSD in Healthy Subjects

Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD With Optional fMRI Sub-Study

A Multi-Site Open-Label Extension Study of MDMA-Assisted Psychotherapy for PTSD

Study Comparing Two Versus Three Active MDMA-assisted Sessions in U.S. Military Veterans With Chronic PTSD

Circulating Oxytocin Changes in Response to the Oxytocin System Stimulator MDMA in Patients With Diabetes Insipidus and Healthy Controls

Effects of MDMA-like Substances in Healthy Subjects

Investigation of Serotonin Neurotransmission in MDMA Users Using Combinated Dexfenfluramine Challenge and PET Imaging

Functional Brain Imaging in Recreational Users of Ecstasy

A Treatment Development Study of MDMA-Assisted Psychotherapy for PTSD

Food Effects on Bioavailability of MDMA in Healthy Volunteers

Social Anxiety MDMA-Assisted Therapy Investigation

Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD

Drug Effects on Interpersonal Interaction

Long-Term Safety and Effectiveness of Manualized MDMA-Assisted Therapy for the Treatment of Posttraumatic Stress Disorder

Correlates of Anxiety Associated With a Life-threatening Illness

Addiction in Intensive Cardiac Care Units

Clinical Pharmacology of MDA [3,4-methylenedioxyamphetamine]

Patient Doctor Lies

Personality and Drug Use (PDU)

Postpartum MDMA Co-occurring PTSD and OUD

Study of Feasibility and Safety of MDMA-Assisted Group Therapy for the Treatment of PTSD in Veterans

Acute Effects of R- and S-MDMA in Healthy Subjects

Sustaining Remission From PTSD Using Tuned Vibroacoustic Stimulation (TVS) Following MDMA-Assisted Psychotherapy

Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social Function

Efficacy and Tolerability of Rimegepant for the Acute Treatment of Migraine in Adults Unsuitable for Triptan Use