Acute toxicity of 3, 4-methylenedioxymethamphetamine (MDMA) in Sprague–Dawley and Dark Agouti rats
A Malpass, JM White, RJ Irvine, AA Somogyi… - Pharmacology …, 1999 - Elsevier
Abstract
Abstract Ingestion of MDMA (“ecstasy”) by humans can cause acute toxicity manifested by hyperthermia and death. Demethylenation of MDMA is catalyzed by cytochrome P-450 2D6 (CYP2D6) and cytochrome P-450 2D1 (CYP2D1) in humans and rats, respectively, and is …
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Last updated: Jul 27, 2020