Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity

Abstract

The ring-substituted amphetamine derivative 3, 4-methylenedioxymethamphetamine (MDMA) or “Ecstasy” is widely used a recreational drug. It stimulates the release and inhibits the reuptake of serotonin (5-HT) and other neurotransmitters such as dopamine to a lesser …