Differences between rats and mice in MDMA (methylenedioxymethylamphetamine) neurotoxicity

BJ Logan, R Laverty, WD Sanderson, YB Yee - European journal of …, 1988 - Elsevier


In both rats and mice a single large dose of methylenedioxymethylamphetamine (MDMA; 25 mg/kg ip) caused a fall 3 h after injection in the content of 5-hydroxytryptamine (5-HT) and 5-hydroxyindoleacetic acid (5-HIAA) in cortex, a fall in noradrenaline in hippocampus and …

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