MDMA (“ecstasy”) impairs learning in the Morris Water Maze and reduces hippocampal LTP in young rats

Abstract

Methylenedioxymethamphetamine (MDMA), an important recreational psychostimulant drug, was examined for its ability to alter visuo-spatial learning and synaptic plasticity. Young rats received MDMA (0.2 and 2 mg/kg sc) twice per day for 6 days while their visuo-spatial …