Sprague–Dawley rats display metabolism-mediated sex differences in the acute toxicity of 3, 4-methylenedioxymethamphetamine (MDMA, ecstasy)

J Fonsart, MC Menet, X Declèves, H Galons… - Toxicology and applied …, 2008 - Elsevier

Author(s): Xavier Decleves

Focus: MDMA


The use of the amphetamine derivative 3, 4-methylenedioxymethamphetamine (MDMA, ecstasy) has been associated with unexplained deaths. Male humans and rodents are more sensitive to acute toxicity than are females, including a potentially lethal hyperthermia …

Last updated: Jul 27, 2020