Persistent MDMA‐induced dopaminergic neurotoxicity in the striatum and substantia nigra of mice

Abstract

Acute administration of repeated doses of 3, 4‐methylenedioxymethamphetamine (MDMA, ecstasy) dramatically reduces striatal dopamine (DA) content, tyrosine hydroxylase (TH), and DA transporter‐immunoreactivity in mice. In this study, we show for the first time the …