Study on the neuroprotective effect of fluoxetine against MDMA-induced neurotoxicity on the serotonin transporter in rat brain using micro-PET

Abstract

Methylenedioxymethamphetamine (MDMA,“ecstasy”) has toxic effects on serotonergic neurons in the brain. Our aim was to determine whether N, N-dimethyl-2-(2-amino-4-[18 F]-fluorophenylthio) benzylamine (4-[18 F]-ADAM; a serotonin transporter imaging agent) and …