The demethylenation of methylenedioxymethamphetamine (“ecstasy”) by debrisoquine hydroxylase (CYP2D6)

GT Tucker, MS Lennard, SW Ellis, HF Woods… - Biochemical …, 1994 - Elsevier

Focus: MDMA


… The des-methyl analogue, tr-methyldopamine, is an indirect dopamine agonist [23, 24 … Kovar K- A, On the metabolism of 3,4-methylenedioxy- methamphetamine (MDMA) in … P450 isozymes responsible for the metabolic activation of methylenedioxymethamphetamine (MDMA) in …

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