Brain serotonin function in MDMA (ecstasy) users: evidence for persisting neurotoxicity

Abstract

3, 4-methylenedioxymethamphetamine (MDMA; ecstasy) is a popular recreational drug, and clinical trials are investigating MDMA as a treatment for anxiety. Animal models suggest that MDMA causes chronic serotonin neurotoxicity, especially in neocortex. Given the role of …