Role of serotonin via 5-HT 2B receptors in the reinforcing effects of MDMA in mice

Abstract

The amphetamine derivative 3, 4-methylenedioxymethamphetamine (MDMA, ecstasy) reverses dopamine and serotonin transporters to produce efflux of dopamine and serotonin, respectively, in regions of the brain that have been implicated in reward. However, the role …