Investigation of the prejunctional α2‐adrenoceptor mediated actions of MDMA in rat atrium and vas deferens

Abstract

We have investigated the effects of methylenedioxymethamphetamine (MDMA,'ecstasy') on peripheral noradrenergic neurotransmission in the rat. In rat atrial slices pre‐incubated with [3H]‐noradrenaline and in the presence of desipramine (1 μm) to prevent effects of MDMA …