Studies on the neuroprotective effect of pentobarbitone on MDMA-induced neurodegeneration

Abstract

Administration of a dose of 15 mg/kg of the recreationally used drug 3, 4-methylenedioxymethamphetamine (MDMA or “ecstasy”) to Dark Agouti rats resulted in an acute hyperthermic response which was followed 7 days later by a marked (≈ 45%) loss of …