In vivo evidence against clomethiazole being neuroprotective against MDMA ('ecstasy')-induced degeneration of rat brain 5-HT nerve terminals by a free radical …

Abstract

Clomethiazole is an effective neuroprotective agent against the degeneration of 5-HT neurones that follows administration of 3, 4-methylenedioxymethamphetamine (MDMA or 'ecstasy'). Since there is good evidence that free radical formation resulting from auto …