In vivo evidence against clomethiazole being neuroprotective against MDMA ('ecstasy')-induced degeneration of rat brain 5-HT nerve terminals by a free radical …

MI Colado, E O'Shea, B Esteban, R Granados… - …, 1999 - Elsevier

Author(s): Maria Esther O´Shea Gaya , Maria Isabel Colado Megía

Focus: MDMA

Abstract:

Clomethiazole is an effective neuroprotective agent against the degeneration of 5-HT neurones that follows administration of 3, 4-methylenedioxymethamphetamine (MDMA or 'ecstasy'). Since there is good evidence that free radical formation resulting from auto …