3,4-Methylenedioxymethamphetamine (MDMA): Stereoselective interactions at brain 5-HT1 and 5-HT2 receptors

Abstract

Methylenedioxymethamphetamine (MDMA), 3, 4-methylenedioxy-amphetamine (MDA), and their optical isomers, were assayed for their affinities at radiolabeled brain serotonin (5-HT 1, 5-HT 2) and dopamine (D 2) binding sites.(R (−)-MDA and R (−)-MDMA) displayed moderate …