3, 4-methylenedioxymethamphetamine (MDMA,“Ecstasy”) induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro

V Setola, SJ Hufeisen, KJ Grande-Allen, I Vesely… - Molecular …, 2003 - ASPET

Author(s): Vincent Setola , Katie Jane Grande-Allen

Focus: MDMA

Abstract:

Recent findings have implicated the 5-hydroxytryptamine 2B (5-HT 2B) serotonin receptor in mediating the heart valve fibroplasia [valvular heart disease (VHD)] and primary pulmonary hypertension observed in patients taking the now-banned appetite suppressant fenfluramine …