Psychological and physiological effects of MDMA (“Ecstasy”) after pretreatment with the 5-HT 2 antagonist ketanserin in healthy humans

Abstract

Abstract MDMA (3, 4-methylenedioxymethamphetamine,“Ecstasy”) mainly releases serotonin and dopamine. In animals, pretreatment with 5-HT 2 antagonists has been shown to attenuate neurochemical and behavioral effects of MDMA. In humans, the role of 5-HT 2 …