Influence of inducers and inhibitors on the metabolism in vitro and neurochemical effects in vivo of MDMA.

R Gollamudi, SF Ali, G Lipe, G Newport, P Webb… - …, 1989 -


(S)-(+)-and (R)-(-)-3, 4-methylenedioxymethamphetamine (MDMA) were metabolized in vitro by rat liver microsomes via N-demethylation to 3, 4-methylenedioxyamphetamine (MDA). Whereas no difference was found in the biotransformation of the two enantiomers in the …

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