In vivo evidence for free radical involvement in the degeneration of rat brain 5‐HT following administration of MDMA ('ecstasy') and p‐chloroamphetamine but not the …

Abstract

Administration of 3, 4‐methylenedioxymethamphetamine (MDMA or 'ecstasy') to several species results in a long lasting neurotoxic degeneration of 5‐hydroxytryptaminergic neurones in several regions of the brain. We have now investigated whether this …