The N-methyl-D-aspartate (NMDA) receptor antagonist, dextrorphan, prevents the neurotoxic effects of 3, 4-methylenedioxymethamphetamine (MDMA) in rats

Abstract

Using the systemically active, non-competitive N-methyl-d-aspartate (NMDA) receptor antagonist dextrorphan, we explored the role of the NMDA receptor-calcium channel complex in the toxic mechanism of action of 3, 4-methylenedioxymethamphetamine …