Repeated administration of MDMA causes transient down-regulation of serotonin 5-HT2 receptors

U Scheffel, JR Lever, M Stathis, GA Ricaurte - Neuropharmacology, 1992 - Elsevier

Abstract

The present study examined short-and long-term effects of MDMA (3, 4-methylenedioxymethamphetamine) on serotonin (5-HT 2 and 5-HT 1c) receptors in the brain of the rat. N1-Methyl-2-[125 I] lysergic acid diethylamide ([125 I] MIL) was used to label these …

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