A study of the mechanism of MDMA ('Ecstasy')‐induced neurotoxicity of 5‐HT neurones using chlormethiazole, dizocilpine and other protective compounds

Abstract

1 An investigation has been made in rats into the neurotoxic effect of the relatively selective 5‐hydroxytryptamine (5‐HT) neurotoxin, 3, 4‐methylenedioxymethamphetamine (MDMA or 'Ecstasy') using chlormethiazole and dizocilpine, both known neuroprotective compounds …