Oral administration of 3, 4-methylenedioxymethamphetamine (MDMA) produces selective serotonergic depletion in the nonhuman primate

Abstract

Abstract MDMA (3, 4-methylenedioxymethamphetamine) has been reported to produce serotonergic depletion in nonhuman primates at doses as low as 2.5 mg/kg (1–2 times the typical human dose). The current study evaluated the dose-response relationships of MDMA …