The hyperthermic and neurotoxic effects of 'Ecstasy'(MDMA) and 3, 4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor …

Abstract

1 The effect of administration of 3, 4‐methylenedioxymethamphetamine (MDMA or 'Ecstasy') and its N‐demethylated product, 3, 4‐methylenedioxyamphetamine (MDA) on both rectal temperature and long term neurotoxic loss of cerebral 5‐hydroxytryptamine (5‐HT) has been …