Effects of cortical serotonin depletion induced by 3, 4-methylenedioxymethamphetamine (MDMA) on behavior, before and after additional cholinergic blockade

Abstract

Repeated treatment with high doses of 3, 4-methylenedioxymethamphetamine (MDMA;" ecstasy") produces a long-lasting depletion of brain serotonin, presumably because of the degeneration of serotonin axon terminals. However, very little is known about the long-term …