Effects of (±) 3, 4-methylenedioxymethamphetamine (MDMA) on brain dopaminergic activity in rats

RT Matthews, TH Champney, GD Frye - Pharmacology Biochemistry and …, 1989 - Elsevier


Abstract Acute treatment with (±) 3, 4-methylenedioxymethamphetamine (MDMA) at high doses (10 and 30 mg/kg, IP), but not lower doses increased locomotor activity in male rats. MDMA did not consistently produce any other stereotyped behaviors at any dose. Dopamine …

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