Nonlinear pharmacokinetics of (±) 3, 4-methylenedioxymethamphetamine (MDMA) and its pharmacodynamic consequences in the rat

Abstract

3, 4-Methylenedioxymethamphetamine (MDMA) is a widely abused illicit drug that can cause severe and even fatal adverse effects. However, interest remains for its possible clinical applications in posttraumatic stress disorder and anxiety treatment. Preclinical …