(±3, 4-Methylenedioxymethamphetamine Selectively Damages Central Serotonergic Neurons in Nonhuman Primates

Abstract

… (\m=+-\)3,4-Methylenedioxymethamphetamine (MDMA) is a … Forexample, l-methyl-4-phenyl- 1,2,3,6-tetrahydropyridine (MPTP) is relatively inactive in rats16,17 but pro¬ foundly toxic in primates.18,19 Con¬ versely, 1,2,3,6-tetrahydro-l-methyl- 4-(metnylpyrrol-2-yl)pyridine, an an …