Neural and cardiac toxicities associated with 3, 4-methylenedioxymethamphetamine (MDMA)

Abstract

(±)-3, 4-Methylenedioxymethamphetamine (MDMA) is a commonly abused illicit drug which affects multiple organ systems. In animals, high-dose administration of MDMA produces deficits in serotonin (5-HT) neurons (eg, depletion of forebrain 5-HT) that have been viewed …