Personality and Drug Use (PDU)

Brief Summary

The study aims to assess whether the use of drugs relates to personality ratings. Specifically, we plan to investigate if people with different histories of substance use differentiate on personality assessments (current and past).

Intervention / Treatment

Condition or Disease

  • Personality


Study Design

Study type: Observational
Status: Withdrawn
Study results: No Results Available
Age: 18 Years and older   (Adult, Older Adult)
Enrollment: 0 ()
Funded by: Industry|Other


Clinical Trial Dates

Start date: Apr 01, 2022
Primary Completion: Apr 01, 2023
Completion Date: Apr 01, 2023
Study First Posted: Jan 06, 2022
Last Updated: Apr 29, 2022

Sponsors / Collaborators

Lead Sponsor: N/A
Responsible Party: N/A

The study aims to assess the association between the use of various substances (including psychedelic and non-psychedelic drugs) and personality profiles. Specifically, the association between past drug usage and personality profiles will be investigated. As psychedelics were found to influence changes in personality over time, the present study aims to measure both the current personality profile (via the Big Five Inventory-44 (BFI)) and perceived retrospective changes in personality (via a self-constructed Retrospective Personality Scale (RPS)). To our knowledge, no study has explored the diversity of substance use histories in relation to individual current and retrospective personality traits and aggregate personality profiles.

This project aims to survey a large number of participants from all around the world, using a mobile app-based survey. The remote character of the study will increase its accessibility and diversity, which are common shortcomings in the psychedelic line of research. Additionally, a remote, anonymous study setup with no face-to-face interactions might help overcome any potential concerns participants may have regarding the sharing of sensitive information (e.g., reports on illicit substance use).

To increase scientific transparency and for educational purposes, the study team plans to share results summaries (comparisons of personalized results with the aggregated ones among participants sharing similar characteristics e.g., age, substance use history), which might be an additional motivating factor for study completion. Lastly, given that drug use in the natural environment (excluding laboratory/experimental setting) is characterized by large substance diversity and poly-drug use, we aim for a large sample size (with a minimum of 36 subjects per substance(s) category) to perform subgroup analyses. Therefore, this large-scale, low-budget, naturalistic, retrospective, observational study aims to shed light on the aforementioned gap in the literature and to lay a foundation of evidence for further (observational and experimental) research within the field.

Eligibility Criteria

Sex: All

More Details

NCT Number: NCT05180149
Acronym: PDU
Study URL:
Last updated: Jun 17, 2022