Houston, Texas, USA

The Safety and Efficacy of Psilocybin in Participants With Treatment Resistant Depression

Completed
Treatment Resistant Depression
Start Date: Mar 2019
Last Updated: Apr 2023
New York, New York, USA / Toronto, Ontario, Canada / Baltimore, Maryland, USA and 22 more
Psilocybin

Low Dose Intravenous Ketamine in Treatment Resistant Depression Patients

Completed
Treatment Resistant Depression
Start Date: Oct 2016
Last Updated: Jan 2022
Houston, Texas, USA
Ketamine

Efficacy And Tolerability Of Sub-Anesthetic Ketamine In Postpartum Depression

Terminated
Post Partum Depression
Start Date: Mar 2019
Last Updated: Sep 2021
Houston, Texas, USA
Ketamine

A Study to Evaluate Ketamine for the Treatment of Rett Syndrome

Completed
Rett Syndrome
Start Date: Mar 2019
Last Updated: Apr 2022
Chicago, Illinois, USA / Boston, Massachusetts, USA / Houston, Texas, USA and 4 more
Ketamine

The UTHealth Ketamine Project

Terminated
Treatment Resistant Depression
Major Depressive Disorder
Bipolar Disorder
Start Date: Nov 2016
Last Updated: Nov 2020
Houston, Texas, USA
Ketamine

Ketamine for Acute Pain Management After Trauma

Completed
Trauma Injury
Pain
Opioid Use
Start Date: Jul 2020
Last Updated: Mar 2023
Houston, Texas, USA
Ketamine

Trial of the Rapid Antisuicidal Effects of Intranasal Ketamine in Comorbid Depression and Alcohol Abuse

Recruiting
Suicidal Ideation
Depression
Alcohol Abuse
Start Date: May 2018
Last Updated: Apr 2019
Houston, Texas, USA
Ketamine

Comparison of Low-dose Ketamine to Opioids in the Management of Acute Pain in Patients Presenting to the Emergency Department With Long Bone Fractures

Withdrawn
Pain, Acute
Start Date: Jan 2022
Last Updated: Apr 2022
Houston, Texas, USA
Ketamine

Optimization of IV Ketamine for Treatment Resistant Depression

Completed
Major Depressive Disorder (MDD)
Treatment Resistant Depression (TRD)
Start Date: Nov 2008
Last Updated: Dec 2013
New York, New York, USA / Houston, Texas, USA
Ketamine

ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD)

Completed
Treatment Resistant Depression
Electroconvulsive Therapy
ECT
Ketamine
Psychiatric Disorder
Depression
Major Depressive Disorder
Major Depressive Episode
Unipolar Depression
Start Date: Apr 2017
Last Updated: Sep 2023
New York, New York, USA / Baltimore, Maryland, USA / Houston, Texas, USA and 2 more
Ketamine

Ketamine for Treatment Resistant Late-Life Depression

Completed
Treatment Resistant Depressive Disorder
Start Date: Oct 2015
Last Updated: Dec 2021
Houston, Texas, USA
Ketamine

Double-Blind, Placebo-Controlled Trial of Ketamine Therapy in Treatment-Resistant Depression (TRD)

Completed
Treatment Resistant Depression
Start Date: Dec 2014
Last Updated: May 2018
New York, New York, USA / Boston, Massachusetts, USA / Dallas, Texas, USA and 3 more
Ketamine

Conscious Sedation Efficacy of the MKO Melt (Midazolam, Ketamine, Ondansetron)

Completed
Cataract
Start Date: Jun 2017
Last Updated: Aug 2018
Houston, Texas, USA
Ketamine

Sequential Therapy for the Treatment of Severe Bipolar Depression.

Completed
Bipolar Depression
Suicidal Ideas
Suicidal Ideation
Suicide, Attempted
Start Date: Jan 2018
Last Updated: May 2021
Houston, Texas, USA / Birmingham, Alabama, USA / Charlotte, North Carolina, USA and 1 more
Ketamine

Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Performed Under General Anesthesia Versus Moderate Sedation

Completed
Mediastinal Lymphadenopathies
Mediastinal Masses
Hilar Lymphadenopathies
Start Date: Nov 2011
Last Updated: Jul 2015
Houston, Texas, USA
Ketamine

Once-Nightly Sodium Oxybate for Treatment of Excessive Daytime Sleepiness and Cataplexy in Narcolepsy

Completed
Excessive Daytime Sleepiness
Cataplexy
Narcolepsy
Start Date: Nov 2016
Last Updated: Mar 2022
Montreal, Quebec, Canada / New York, New York, USA / Boulder, Colorado, USA and 50 more
GHB

Safety and Tolerability Study Comparing Sodium Oxybate Given as an Oral Solution to a Single-blinded Combination of Oral Tablets Plus Oral Solution in Subjects With Fibromyalgia

Completed
Fibromyalgia
Start Date: Mar 2010
Last Updated: Aug 2011
Austin, Texas, USA / Houston, Texas, USA / Sacramento, California, USA and 26 more
GHB

Safety and Efficacy Study of Xyrem® (Sodium Oxybate) in Subjects With Fibromyalgia.

Completed
Fibromyalgia
Start Date: Dec 2006
Last Updated: Mar 2012
London, England, United Kingdom / Chicago, Illinois, USA / Austin, Texas, USA and 83 more
GHB

Safety and Efficacy of Xyrem Oral Solution (Sodium Oxybate) Compared With Placebo in Narcoleptic Patients

Completed
Narcolepsy
Start Date: Dec 2000
Last Updated: Jun 2005
Vancouver, British Columbia, Canada / Montreal, Quebec, Canada / New York, New York, USA and 38 more
GHB

A Safety and Efficacy Study of Xyrem® (Sodium Oxybate) to Treat Fibromyalgia.

Completed
Fibromyalgia
Start Date: Dec 2006
Last Updated: Jan 2012
London, England, United Kingdom / Chicago, Illinois, USA / Arlington, Virginia, USA and 101 more
GHB

Long Term Follow Up Study to COMP 001 And COMP 003 Trials (P-TRD LTFU)

Recruiting
Treatment Resistant Depression
Start Date: Jul 2020
Last Updated: Mar 2021
London, England, United Kingdom / Dublin, Ireland / Atlanta, Georgia, USA and 5 more
Psilocybin

A Multicenter Study of the Efficacy and Safety of Xyrem With an Open- Label Pharmacokinetic Evaluation and Safety Extension in Pediatric Subjects With Narcolepsy With Cataplexy

Completed
Narcolepsy With Cataplexy
Start Date: Oct 2014
Last Updated: Apr 2019
Chicago, Illinois, USA / Houston, Texas, USA / Paris, Île-de-France, France and 17 more
GHB

A Safety and Efficacy Study of Xyrem® in Subjects With Fibromyalgia

Completed
Fibromyalgia
Start Date: Aug 2006
Last Updated: Dec 2011
Austin, Texas, USA / Houston, Texas, USA / Sacramento, California, USA and 60 more
GHB