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  • Ibogaine: a review • The ibogaine medical subculture • Treatment of acute opioid withdrawal with ibogaine • Effects and aftereffects of ibogaine on morphine self-administration in rats • Inhibitory effects of ibogaine on cocaine self-administration in rats • Mechanisms of Antiaddictive Actions of Ibogainea • Ibogaine possesses a selective affinity for σ2 receptors • Medication Development of Ibogaine as a Pharmacotherapy for Drug Dependencea • Ibogaine: complex pharmacokinetics, concerns for safety, and preliminary efficacy measures • Ibogaine neurotoxicity: a re-evaluation • Noncompetitive functional inhibition at diverse, human nicotinic acetylcholine receptor subtypes by bupropion, phencyclidine, and ibogaine • Mechanisms of action of ibogaine and harmaline congeners based on radioligand binding studies • Radioligand-binding study of noribogaine, a likely metabolite of ibogaine • Ibogaine antagonizes cocaine-induced locomotor stimulation in mice • A preliminary investigation of ibogaine: case reports and recommendations for further study • Ibogaine in the treatment of heroin withdrawal • Effects of ibogaine on acute signs of morphine withdrawal in rats: independence from tremor • Degeneration of Purkinje cells in parasagittal zones of the cerebellar vermis after treatment with ibogaine or harmaline • Ibogaine-like effects of noribogaine in rats • Attenuation of alcohol intake by ibogaine in three strains of alcohol-preferring rats • Effect of ibogaine on naloxone-precipitated withdrawal syndrome in chronic morphine-dependent rats. • Ibogaine and its congeners are σ2 receptor-selective ligands with moderate affinity • NMDA antagonist properties of the putative antiaddictive drug, ibogaine. • Ibogaine induces glial activation in parasagittal zones of the cerebellum • Identification of a primary metabolite of ibogaine that targets serotonin transporters and elevates serotonin • Ibogaine reduces preference for cocaine consumption in C57BL/6By mice • Tissue distribution of ibogaine after intraperitoneal and subcutaneous administration • Interactions between ibogaine, a potential anti-addictive agent, and morphine: an in vivo microdialysis study • Ibogaine in the treatment of substance dependence • Fatalities temporally associated with the ingestion of ibogaine • Pharmacodynamics and therapeutic applications of iboga and ibogaine • Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport • Glial cell line-derived neurotrophic factor mediates the desirable actions of the anti-addiction drug ibogaine against alcohol consumption • Chemical Transformations of Ibogaine • The olivocerebellar projection mediates ibogaine-induced degeneration of Purkinje cells: a model of indirect, trans-synaptic excitotoxicity • The Alkaloids of Tabernanthe iboga. Part IV.1 The Structures of Ibogamine, Ibogaine, Tabernanthine and Voacangine • Use of ibogaine for treating neuropathic pain • Ibogaine therapy: A'Vast, uncontrolled experiment' • The mechanistic basis for noncompetitive ibogaine inhibition of serotonin and dopamine transporters • Sex differences in ibogaine antagonism of morphine-induced locomotor activity and in ibogaine brain levels and metabolism • Acute and prolonged effects of ibogaine on brain dopamine metabolism and morphine-induced locomotor activity in rats • Treatment of opioid use disorder with ibogaine: detoxification and drug use outcomes • 18‐Methoxycoronaridine (18‐MC) and Ibogaine: Comparison of antiaddictive efficacy, toxicity, and mechanisms of action • Ibogaine and the dopaminergic response to nicotine • Ibogaine: a potent noncompetitive blocker of ganglionic/neuronal nicotinic receptors • Attenuation of alcohol consumption by a novel nontoxic ibogaine analogue (18-methoxycoronaridine) in alcohol-preferring rats • The inhibitory effect of norharman on morphine withdrawal syndrome in rats: comparison with ibogaine • The putative anti-addictive drug ibogaine is a competitive inhibitor of MK-801 binding to the NMDA receptor complex • Excitotoxic insult due to ibogaine leads to delayed induction of neuronal NOS in Purkinje cells. • Ibogaine, a noncompetitive inhibitor of serotonin transport, acts by stabilizing the cytoplasm-facing state of the transporter • How toxic is ibogaine? • Ibogaine, an anti-addictive drug: pharmacology and time to go further in development. A narrative review • Ibogaine fails to reduce naloxone-precipitated withdrawal in the morphine-dependent rat • Interaction of ibogaine and d-amphetamine: in vivo microdialysis and motor behavior in rats • Potentiation action of ibogaine (bogadin TM) on morphine analgesia • Treating drug dependence with the aid of ibogaine: A retrospective study • The structure of ibogaine • Structurally modified ibogaine analogs exhibit differing affinities for NMDA receptors • Pharmacological screen for activities of 12-hydroxyibogamine: a primary metabolite of the indole alkaloid ibogaine • Cytochrome P4502D6 catalyzes the O-demethylation of the psychoactive alkaloid ibogaine to 12-hydroxyibogamine • Effects of ibogaine on naloxone‐precipitated withdrawal in morphine‐dependent mice • Ibogaine block of the NMDA receptor: in vitro and in vivo studies • Long-QT syndrome induced by the antiaddiction drug ibogaine • Interactions between ibogaine and cocaine in rats: in vivo microdialysis and motor behavior. • Neurochemical and behavioural interactions between ibogaine and nicotine in the rat • In vivo neurobiological effects of ibogaine and its O-desmethyl metabolite, 12-hydroxyibogamine (noribogaine), in rats • Unique and potent effects of acute ibogaine on zebrafish: the developing utility of novel aquatic models for hallucinogenic drug research • Properties of ibogaine and its principal metabolite (12-hydroxyibogamine) at the MK-801 binding site of the NMDA receptor complex • Iboga Alkaloids. II.1 the Structures of Ibogaine, Ibogamine and Tabernanthine • Psychedelics as medicines for substance abuse rehabilitation: evaluating treatments with LSD, Peyote, Ibogaine and Ayahuasca • Comparison of the behavioral effects of ibogaine from three sources: mediation of discriminative activity • Effects of ibogaine on responding maintained by food, cocaine and heroin reinforcement in rats • The use of ibogaine in the treatment of addictions • High affinity ibogaine binding to a mu opioid agonist site • Prior morphine exposure enhances ibogaine antagonism of morphine-induced locomotor stimulation • Mechanisms of action of ibogaine: relevance to putative therapeutic effects and development of a safer iboga alkaloid congener • Ibogaine-associated ventricular tachyarrhythmias • Comparative neuropharmacology of ibogaine and its O-desmethyl metabolite, noribogaine • The anti-addiction drug ibogaine and the heart: a delicate relation • Life-threatening complications of ibogaine: three case reports • Ibogaine modulates cocaine responses which are altered due to environmental habituation: in vivo microvoltammetric and behavioral studies • Acute toxicity of ibogaine and noribogaine • Ibogaine treatment outcomes for opioid dependence from a twelve-month follow-up observational study • Ibogaine selectively inhibits nicotinic receptor-mediated catecholamine release • Ibogaine affects brain energy metabolism • Ibogaine attenuation of morphine withdrawal in mice: role of glutamate N-methyl-D-aspartate receptors • Ibogaine reduces amphetamine-induced locomotor stimulation in C57BL/6By mice, but stimulates locomotor activity in rats • Facilitation of memory retrieval by the “anti-addictive” alkaloid, ibogaine • Cardiac arrest after ibogaine ingestion • Ibogaine and cocaine abuse: pharmacological interactions at dopamine and serotonin receptors • Bioactive tricyclic ibogaine analogs • DARK classics in chemical neuroscience: Ibogaine • Anti‐addiction drug ibogaine inhibits hERG channels: a cardiac arrhythmia risk • Fatalities after taking ibogaine in addiction treatment could be related to sudden cardiac death caused by autonomic dysfunction • A contemporary history of ibogaine in the United States and Europe • Autoregulation of glial cell line‐derived neurotrophic factor expression: implications for the long‐lasting actions of the anti‐addiction drug, Ibogaine • Differential effects of ibogaine pretreatment on brain levels of morphine and (+)-amphetamine • A dose-response study of ibogaine-induced neuropathology in the rat cerebellum • Evidence that ibogaine releases dopamine from the cytoplasmic pool in isolated mouse striatum • Ibogaine, a putatively anti-addictive alkaloid • Stimulus effects of ibogaine in rats trained with yohimbine, DOM, or LSD • Case studies of ibogaine treatment: implications for patient management strategies • Evidence for roles of κ-opioid and NMDA receptors in the mechanism of action of ibogaine • Identification and Quantitation of Ibogaine and an o-Demethylated Metabolite in Brain and Biological Fluids Using Gas Chromatography-Mass Spectrometry • Ibogaine related sudden death: a case report • Long-lasting ibogaine protection against NMDA-induced convulsions in mice • Distribution of Ibogaine and Noribogaine in a Man Following a Poisoning Involving Root Bark of the Tabernanthe iboga Shrub • Modulation of morphine-induced antinociception by ibogaine and noribogaine • Local effects of ibogaine on extracellular levels of dopamine and its metabolites in nucleus accumbens and striatum: interactions with d-amphetamine • Identification and quantification of the indole alkaloid ibogaine in biological samples by gas chromatography-mass spectrometry • Total synthesis of ibogaine, epiibogaine and their analogues • Neuroendocrine and neurochemical effects of acute ibogaine administration: a time course evaluation • Effect of ibogaine on serotonergic and dopaminergic interactions in striatum from mice and rats • Noribogaine (12‐hydroxyibogamine): a biologically active metabolite of the antiaddictive drug ibogaine • Behavioral and biochemical evidence for a nonessential 5-HT2A component of the ibogaine-induced discriminative stimulus • Effects of ibogaine, and cocaine and morphine after ibogaine, on ventral tegmental dopamine neurons • Noribogaine generalization to the ibogaine stimulus: correlation with noribogaine concentration in rat brain • Noribogaine, but not 18‐MC, exhibits similar actions as ibogaine on GDNF expression and ethanol self‐administration • Ibogaine and the inhibition of acetylcholinesterase • Ibogaine acts at the nicotinic acetylcholine receptor to inhibit catecholamine release • The need for ibogaine in drug and alcohol addiction treatment • Effects of chronic ibogaine treatment on cerebellar Purkinje cells in the rat • Ibogaine effects on sweet preference and amphetamine induced locomotion: implications for drug addiction • Determination of ibogaine in plasma by gas chromatography-chemical ionization mass spectrometry • Neuropharmacological characterization of local ibogaine effects on dopamine release • Effect of ibogaine on cocaine-induced efflux of dopamine and serotonin from mouse striatum • Effects of ibogaine on sensory-motor function, activity, and spatial learning in rats • Ibogaine and addiction in the animal model, a systematic review and meta-analysis • Ibogaine and noribogaine: comparing parent compound to metabolite • Growing menace of ibogaine toxicity • Modified Ibogaine Fragments: Synthesis and Preliminary Pharmacological Characterization of 3-Ethyl-5-phenyl-1,2,3,4,5,6-hexahydroazepino … • Anti-addiction drug ibogaine inhibits voltage-gated ionic currents: a study to assess the drug's cardiac ion channel profile • Differential effects of ibogaine on behavioural and dopamine sensitization to cocaine • Ibogaine reduces organ colonization in murine systemic and gastrointestinal Candida albicans infections • Ibogaine as a glutamate antagonist: relevance to its putative antiaddictive properties • Ibogaine analogues. Synthesis and preliminary pharmacological evaluation of 7-heteroaryl-2-azabicyclo oct-7-enes • Changes in withdrawal and craving scores in participants undergoing opioid detoxification utilizing ibogaine • The identification of ibogaine in biological material • Ibogaine alters synaptosomal and glial glutamate release and uptake • Ibogaine: Proceedings from the First International Conference • Abbreviated ibogaine congeners. Synthesis and reactions of tropan-3-yl-2-and-3-indoles. Investigation of an unusual isomerization of 2-substituted indoles using … • Responses of the extrapyramidal and limbic substance P systems to ibogaine and cocaine treatments • Use of ibogaine in reducing excitotoxic brain damage • Ibogaine attenuates morphine-induced conditioned place preference. • Prior morphine exposure enhances ibogaine antagonism of morphine-induced dopamine release in rats • Interaction of ibogaine with human α3β4-nicotinic acetylcholine receptors in different conformational states • Ibogaine signals addiction genes and methamphetamine alteration of long‐term potentiation • Drug discrimination studies with ibogaine • Anxiogenic action of ibogaine • Ibogaine and Subjective Experience: Transformative States and Psychopharmacotherapy in the Treatment of Opioid Use Disorder • Ibogaine and noribogaine potentiate the inhibition of adenylyl cyclase activity by opioid and 5-HT receptors • The effect of ibogaine on κ-opioid-and 5-HT3-induced changes in stimulation-evoked dopamine release in vitro from striatum of C57BL/6BY mice • Ibogaine for treating drug dependence. What is a safe dose? • Effect of Ibogaine on the Various Sites of the NMDA Receptor Complex and Sigma Binding Sites in Rat Braina • The effects of ibogaine on dopamine and serotonin transport in rat brain synaptosomes • Mechanism of hERG channel block by the psychoactive indole alkaloid ibogaine • Determination of ibogaine and 12-hydroxy-ibogamine in plasma by gas chromatography-positive ion chemical ionization-mass spectrometry • Effects of LSD 25, BOL 148, bufotenine, mescaline and ibogaine on the potentiation of hexobarbital hypnosis produced by serotonin and reserpine • Cytochrome P450 and O-methyltransferase catalyze the final steps in the biosynthesis of the anti-addictive alkaloid ibogaine from Tabernanthe iboga • Ibogaine detoxification transitions opioid and cocaine abusers between dependence and abstinence: clinical observations and treatment outcomes • Characterization of the discriminable stimulus produced by 2‐BFI: effects of imidazoline I2‐site ligands, MAOIs, β‐carbolines, agmatine and ibogaine • Characterization of multiple sites of action of ibogaine • Differential responses by neurotensin systems in extrapyramidal and limbic structures to ibogaine and cocaine • Effects of ibogaine on the development of tolerance to antinociceptive action of μ-, δ-and κ-opioid receptor agonists in mice • Ibogaine enhances the expression of locomotor sensitization in rats chronically treated with cocaine • Alteration in electroencephalogram and monoamine concentrations in rat brain following ibogaine treatment • Ibogaine therapy for substance abuse disorders • Comparative neurobiological effects of ibogaine and MK-801 in rats • Effects of ibogaine and noribogaine on the antinociceptive action of μ-, δ-and κ-opioid receptor agonists in mice • The effect of ibogaine on sigma-and NMDA-receptor-mediated release of dopamine • Ibogaine acute administration in rats promotes wakefulness, long-lasting REM sleep suppression, and a distinctive motor profile • The effects of sigma, PCP, and opiate receptor ligands in rats trained with ibogaine as a discriminative stimulus • Ibogaine interferes with motivational and somatic effects of naloxone-precipitated withdrawal from acutely administered morphine • Tabernanthine, ibogaine containing analgesic compositions • Determination of ibogaine and noribogaine in biological fluids and hair by LC–MS/MS after Tabernanthe iboga abuse: Iboga alkaloids distribution in a drowning death … • A qualitative/quantitative approach for the detection of 37 tryptamine-derived designer drugs, 5 β-carbolines, ibogaine, and yohimbine in human urine and plasma … • Derivatives of ibogamine, ibogaine and ibogaline lactams • Disposition of ibogaine in the rat • Enhancement of morphine antinociception by ibogaine and noribogaine in morphine-tolerant mice • Pharmacokinetic characterization of the indole alkaloid ibogaine in rats • Effects of ibogaine and noribogaine on phosphoinositide hydrolysis • Treating drug dependence with the aid of ibogaine: A qualitative study • Ibogaine interferes with the establishment of amphetamine place preference learning. • Influence of CYP2D6 activity on the pharmacokinetics and pharmacodynamics of a single 20 mg dose of ibogaine in healthy volunteers • Failure of ibogaine to produce phencyclidine-like discriminative stimulus effects in rats and monkeys • In Vivo Ibogaine Blockade and In Vitro PKC Action of Cocainea • Effects of ibogaine on performance in the 8-arm radial maze • From the roots up: ibogaine and addict self-help • Ibogaine blocked methamphetamine-induced hyperthermia and induction of heat shock protein in mice • Ibogaine fails to interrupt the expression of a previously established one-trial morphine place preference. • Differential effects of ibogaine on local cerebral glucose utilization in drug-naive and morphine-dependent rats • Effects of low dose ibogaine on subjective mood state and psychological performance • Mania following use of ibogaine: A case series • Liquid chromatography–electrospray mass spectrometry determination of ibogaine and noribogaine in human plasma and whole blood: Application to a poisoning … • Ibogaine, an anti-addictive drug: pharmacology and time to go further in development. A narrative review • Metabolism of 18-methoxycoronaridine, an ibogaine analog, to 18-hydroxycoronaridine by genetically variable CYP2C19 • Acute ibogaine injection induces expression of the immediate early genes, egr-1 and c-fos, in mouse brain • Internet-purchased ibogaine toxicity confirmed with serum, urine, and product content levels • Remission of severe opioid Use disorder with ibogaine: a case report • Ibogaine neurotoxicity assessment: electrophysiological, neurochemical, and neurohistological methods • Modulation of the effects of rewarding drugs by ibogaine • Manual for ibogaine therapy: screening, safety, monitoring & aftercare • Morphing of Ibogaine: A Successful Attempt into the Search for Sigma-2 Receptor Ligands • The antiaddictive effects of ibogaine: A systematic literature review of human studies • Acute and chronic administration of ibogaine to the rat results in astrogliosis that is not confined to the cerebellar vermis • The effects of noribogaine and harmaline in rats trained with ibogaine as a discriminative stimulus • Cholecystokinin octapeptide (CCK-8), ceruletide and analogues of ceruletide: Effects on tremors induced by oxotremorine, harmine and ibogaine a comparison with … • Subjective effectiveness of ibogaine treatment for problematic opioid consumption: Short-and long-term outcomes and current psychological functioning • A phenomenological analysis of the subjective experience elicited by ibogaine in the context of a drug dependence treatment • Metabolic plasticity and the energy economizing effect of ibogaine, the principal alkaloid of Tabernanthe iboga • Neurochemical and neuroendocrine effects of ibogaine in rats: Comparison to MK‐801 • Ibogaine-associated cardiac arrest and death: case report and review of the literature • Fatal Case of a 27‐Year‐Old Male After Taking Iboga in Withdrawal Treatment: GC‐MS/MS Determination of Ibogaine and Ibogamine in Iboga Roots and Postmortem … • Ibogaine and a total alkaloidal extract of Voacanga africana modulate neuronal excitability and synaptic transmission in the rat parabrachial nucleus in vitro • Toxicokinetics of ibogaine and noribogaine in a patient with prolonged multiple cardiac arrhythmias after ingestion of internet purchased ibogaine • Ibogaine therapy for addiction: Consumer views from online fora • The mystery of ibogaine: can an African psychedelic cure addiction? • Ibogaine-associated psychosis in schizophrenia: a case report • Administration of a non-NMDA antagonist, GYKI 52466, increases excitotoxic Purkinje cell degeneration caused by ibogaine • A mixed-method analysis of persisting effects associated with positive outcomes following ibogaine detoxification • Comparison of the hallucinogenic indole alkaloids ibogaine and harmaline for potential immunomodulatory activity • Ibogaine: A novel anti-addictive compound • Pretreatment with the putative anti-addictive drug, ibogaine, increases the potency of cocaine to elicit locomotor responding: a study with acute and chronic cocaine … • Quantification of Anti‐Addictive Alkaloids Ibogaine and Voacangine in In Vivo‐ and In Vitro‐Grown Plants of Two Mexican Tabernaemontana Species • Ibogaine pretreatment dramatically enhances the dynorphin response to cocaine • Structure of ibogaine • Further investigations of the serotonergic properties of the ibogaine-induced discriminative stimulus. • Metallation/reduction as a new approach to tritium labeling. The synthesis of ibogaine • Ibogaine in the treatment of narcotic withdrawal • The development and expression of locomotor sensitization to nicotine in the presence of ibogaine • 100 years of ibogaine: neurochemical and pharmacological actions of a putative anti-addictive drug. • Ibogaine in the 21st century: boosters, tuneups and maintenance • The anti-addictive drug ibogaine modulates voltage-gated ion channels and may trigger cardiac arrhythmias • Quantitation of ibogaine and 12-hydroxyibogamine in human plasma by liquid chromatography with fluorimetric detection • A preliminary report on the safety and pharmacokinetics of ibogaine • Sur l'ibogaine • A Single Administration of the Atypical Psychedelic Ibogaine or its Metabolite Noribogaine Induces an Antidepressant-like Effect in Rats • Examination of the phenomenology of the ibogaine treatment experience: Role of altered states of consciousness and psychedelic experiences • Ibogaine administration modifies GDNF and BDNF expression in brain regions involved in mesocorticolimbic and nigral dopaminergic circuits • Ibogaine as a treatment for substance misuse: potential benefits and practical dangers • Understanding the healing potential of ibogaine through a comparative and interpretive phenomenology of the visionary experience • Methods and compositions for reducing tolerance to opioid analgesics using ibogaine and derivatives thereof • Detection and Identification of Ibogaine and Heroin • The effects of β-carbolines in rats trained with ibogaine as a discriminative stimulus • Ibogaine-structure, influence on human body, clinical relevance • Ibogaine labeling with 99mTc-tricarbonyl: synthesis and transport at the mouse blood–brain barrier • Detoxification from methadone using low, repeated, and increasing doses of ibogaine: A case report • Breaking the cycle of opioid use disorder with ibogaine • Methods for acute and long-term treatment of substance abuse using ibogaine • Induction of energy metabolism related enzymes in yeast Saccharomyces cerevisiae exposed to ibogaine is adaptation to acute decrease in ATP energy pool • A case report SPECT study and theoretical rationale for the sequential administration of ibogaine and 5-MeO-DMT in the treatment of alcohol use disorder • Solution-phase parallel synthesis of N, 6-disubstituted isoquinuclidines as ibogaine analogs • “Herbal seizures”–atypical symptoms after ibogaine intoxication: a case report • Structure–activity relationship of ibogaine analogs interacting with nicotinic acetylcholine receptors in different conformational states • Liquid chromatography-electrospray mass spectrometry determination of ibogaine and 12-hydroxy-ibogamine in human urine • A phenomenological investigation into the lived experience of ibogaine and its potential to treat opioid use disorders • Extraction and Conversion Studies of the Antiaddictive Alkaloids Coronaridine, Ibogamine, Voacangine, and Ibogaine from Two Mexican Tabernaemontana Species … • Ex vivo effects of ibogaine on the activity of antioxidative enzymes in human erythrocytes • Investigation into pharmacokinetic properties of active alkaloid ibogaine and its metabolite noribogaine • Ibogaine therapy in the treatment of opiate dependency • Ibogaine interferes with the establishment of conditioned taste avoidance produced by morphine and lithium • Neuropharmacological studies on ibogaine, an indole alkaloid with central-stimulant properties. • Anti-addiction drug ibogaine prolongs the action potential in human induced pluripotent stem cell-derived cardiomyocytes • Cardiac arrest after ibogaine intoxication • The effects of ibogaine on uterine smooth muscle contractions: relation to the activity of antioxidant enzymes • Ibogaine and Noribogaine: Structural Analysis and Stability Studies. Use of LC‐MS to Determine Alkaloid Contents of the Root Bark of Tabernanthe Iboga • Ibogaine produces neurodegeneration in rat, but not mouse, cerebellum: Neurohistological biomarkers of Purkinje cell loss • Assessment of neurotoxicity from potential medications for drug abuse: ibogaine testing and brain imaging • Ibogaine--the substance for treatment of toxicomania. Neurochemical and pharmacological action • The Ibogaine Experience: A Qualitative Study on the Acute Subjective Effects of Ibogaine • Ibogaine and the treatment of opiate addiction • Combating substance abuse with ibogaine: Pre-and posttreatment recommendations and an example of successive model fitting analyses • A new approach to tritium labelling; the synthesis of ibogaine • Application of electrophysiological method to study interactions between ibogaine and cocaine • Ibogaine II: down memory lane; does one trip equal 30 years on a therapist's couch? • Effect of ibogaine on the development of tolerance to the analgesic effect of morphine. • Pharmacological comparison of the effect of ibogaine and 18‐methoxycoronaridine on isolated smooth muscle from the rat and guinea‐pig • Life after ibogaine • Ibogaine: therapeutic miracle • A COMPARATIVE STUDY ON THE TOXICITY OF IBOGAINE AND SEROTONIN. • Ibogaine Treatment in Aotearoa/New Zealand: Developing a unique model of practice • Cardiac arrest after ibogaine ingestion • Hallucinogen persisting perception disorder after ibogaine treatment for opioid dependence • Ibogaine Consumption With Seizure-Like Episodes, QTc-Prolongation, and Captured Cardiac Dysrhythmias • Methods and compositions for treating depression using ibogaine • An analytical study of iboga alkaloids contained in Tabernanthe iboga-derived products offered by ibogaine treatment providers • Ibogaine in acute opioid withdrawal: An open label case series • Low dose administration of ibogaine for treating nicotine addiction and preventing relapse of nicotine use • Ibogaine offers an alternative approach for treating opiate addiction • NOS and fos in Rat and Mouse Brain Regions: Possible Relation to Ibogaine‐Induced Purkinje Cell Loss • Analysis of the cardiovascular action of ibogaine hydrochloride. • Anesthesia for opiate detoxification and the ibogaine controversy • Development of novel medications for drug addiction: The legacy of an African shrub • Observations on treatment with ibogaine. • Changes in gene expression and signal transduction following ibogaine treatment • The anti-addiction drug ibogaine inhibits cardiac ion channels: a study to assess the drug's proarrhythmic potential • Novel treatment of opioid use disorder using ibogaine and iboga in two adults • … effect of alkaloids from Tabernanthe iboga H. Bn. on the response of isolated organs to catecholamines and the possible role of calcium exchange. Case of Ibogaine • Methods for acute and long-term treatment of alcohol dependence using ibogaine • The visionary cure of the addiction war? Ibogaine: social context, subcultural identity, and implications for drug policy • Biosynthesis of the Iboga alkaloids: the incorporation of tryptophan-3-C14 into ibogaine • lbogaine Alters Cocaine-Induced Biogenic Amine and Psychostimulant Dysfunction but not GBR-12935 Binding to the Dopamine Transporter Protein • N-(Hydroxymethyl) ibogaine • Gamma band alterations and REM-like traits underpin the acute effect of the atypical psychedelic ibogaine • Interactions between ibogaine and morphine: Neuropharmacological and pharmacokinetic determinants. • Detection de l'ibogaine dans les liquides organiques • … of Ibogaine and Ibogaine-Related Alkaloids. in The Alkaloids. Chemistry and Biology Pharmacology of Ibogaine and Ibogaine-Related Alkaloids. in The … • N-(Hydroxymethyl) ibogaine • Gamma band alterations and REM-like traits underpin the acute effect of the atypical psychedelic ibogaine • Interactions between ibogaine and morphine: Neuropharmacological and pharmacokinetic determinants. • Detection de l'ibogaine dans les liquides organiques • … of Ibogaine and Ibogaine-Related Alkaloids. in The Alkaloids. Chemistry and Biology Pharmacology of Ibogaine and Ibogaine-Related Alkaloids. in The … • N-(Hydroxymethyl) ibogaine • Gamma band alterations and REM-like traits underpin the acute effect of the atypical psychedelic ibogaine • Interactions between ibogaine and morphine: Neuropharmacological and pharmacokinetic determinants. • Detection de l'ibogaine dans les liquides organiques • N-(Hydroxymethyl) ibogaine • Gamma band alterations and REM-like traits underpin the acute effect of the atypical psychedelic ibogaine • Interactions between ibogaine and morphine: Neuropharmacological and pharmacokinetic determinants. • Gamma band alterations and REM-like traits underpin the acute effect of the atypical psychedelic ibogaine • Interactions between ibogaine and morphine: Neuropharmacological and pharmacokinetic determinants. • Gamma band alterations and REM-like traits underpin the acute effect of the atypical psychedelic ibogaine • Interactions between ibogaine and morphine: Neuropharmacological and pharmacokinetic determinants. • Methods for the detection and determination of ibogaine in biological materials. • A case of QT prolongation and torsades de pointes caused by ibogaine toxicity • Anti-addiction drug ibogaine on trial • Ibogaine Toxicity In A Case Of Good Intentions • IBOGAINE MAY HELP DRUG ADDICTS LIVE THE 'NEVER AGAIN' • Ibogaine Binds Human Serotonin Transporter in Multiple Functional States • QTC prolongation progressing to torsade de pointes secondary to ibogaine ingestion • Experiences of opioid detoxification using ibogaine in various treatment settings: Exploring ibogaine users' motivations, understanding of risks, and effects of ibogaine … • An approach to the synthesis of ibogaine • Psychedelics and quasi-psychedelics in the light of contemporary research: Medical cannabis, MDMA, salvinorin A, ibogaine and ayahuasca • Effects of ibogaine per os application on redox homeostasis in rat liver and erythrocytes • A tropane-based ibogaine analog rescues folding-deficient SERT and DAT • Potential use of medicinal plants in the treatment of alcoholism • Ibogaine modifies GDNF, BDNF and NGF expression in brain regions involved in mesocorticolimbic and nigral dopaminergic circuits • Thin Layer Chromatography of Lysergic Acid Diethylamide (LSD), N, N Dimethyl Tryptamine (DMT), Methylene Dioxyphenyl Isopropylamine (STP), and Ibogaine • Methods and compositions for ibogaine treatment of impulse control disorder, anxiety-related disorders, violence and/or anger, or regulating food intake • Serotonin transporter–ibogaine complexes illuminate mechanisms of inhibition and transport • Gas chromatographic determination of iboga ine in biological fluids • Ibogaine • Ibogaine overdose • Ibogaine overdose • Clinical and Demographic Profile Analysis of Patients Receiving Ibogaine Treatment for Substance Use Disorders in Mexico • Ibogaine overdose • Ibogaine abuse • Ibogaine: History, Pharmacology, Spirituality, & Clinical Data • Ibogaine “ • The Phenomenology of Ibogaine-assisted Addiction Therapy: Understanding the Role of the Visionary Experience in Healing • Pharmacology of ibogaine and ibogaine-related alkaloids
  • Preliminary Efficacy and Safety of Ibogaine in the Treatment of Methadone Detoxification • Ibogaine in the Treatment of Alcoholism: a Randomized, Double-blind, Placebo-controlled, Escalating-dose, Phase 2 Trial • Personality and Drug Use (PDU)


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  • Ketamine • Ketamine and ketamine metabolite pharmacology: insights into therapeutic mechanisms • Antidepressant effects of ketamine in depressed patients • Ketamine use: a review • Ketamine • Ketamine—its pharmacology and therapeutic uses • Ketamine for perioperative pain management • Ketamine • Ketamine infusions: pharmacokinetics and clinical effects • Ketamine: teaching an old drug new tricks • Subanesthetic doses of ketamine stimulate psychosis in schizophrenia • Effects of ketamine in normal and schizophrenic volunteers • Ketamine in dogs. • Pharmacokinetics of ketamine in man. • Perioperative ketamine for acute postoperative pain • NMDAR inhibition-independent antidepressant actions of ketamine metabolites • Pharmacology of ketamine isomers in surgical patients • Mechanisms of ketamine action as an antidepressant • Opiate receptor mediation of ketamine analgesia • Taming the ketamine tiger • Cardiovascular effects of anesthetic induction with ketamine • Ketamine-associated ulcerative cystitis: a new clinical entity • A systematic review of intravenous ketamine for postoperative analgesia • Pharmacokinetics and analgesic effect of ketamine in man • Ketamine-induced neuronal cell death in the perinatal rhesus monkey • Ketamine • Ketamine activates psychosis and alters limbic blood flow in schizophrenia. • Circulatory responses to ketamine anesthesia • Ketamine controls prolonged status epilepticus • Ketamine • Ketamine: its mechanism (s) of action and unusual clinical uses. • Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans: psychotomimetic, perceptual, cognitive, and neuroendocrine responses • Signaling pathways underlying the rapid antidepressant actions of ketamine • R (−)-ketamine shows greater potency and longer lasting antidepressant effects than S (+)-ketamine • Ketamine and postoperative pain–a quantitative systematic review of randomised trials • Ketamine for chronic pain: risks and benefits • Comparative pharmacology of the ketamine isomers: studies in volunteers • Ketamine blocks bursting in the lateral habenula to rapidly relieve depression • Preemptive effect of fentanyl and ketamine on postoperative pain and wound hyperalgesia. • Pharmacokinetics and analgesic effects of im and oral ketamine • Ketamine‐associated bladder dysfunction • The role of ketamine in pain management • Attenuation of antidepressant effects of ketamine by opioid receptor antagonism • Ketamine-induced exacerbation of psychotic symptoms and cognitive impairment in neuroleptic-free schizophrenics • Illicit use of ketamine in Scotland • Ketamine effects on brain GABA and glutamate levels with 1H-MRS: relationship to ketamine-induced psychopathology • Ketamine: behavioral effects of subanesthetic doses • Ketamine sedation for pediatric procedures: part 2, review and implications • Antidepressant potential of (R)-ketamine in rodent models: comparison with (S)-ketamine • NMDA receptor function and human cognition: the effects of ketamine in healthy volunteers • Remifentanil-induced postoperative hyperalgesia and its prevention with small-dose ketamine • Stereoselective pharmacokinetics of ketamine: R(−)‐Ketamine inhibits the elimination of S(+)‐ketamine • Ketamine disposition in children and adults • Oral ketamine preanesthetic medication in children • Medetomidine Ketamine Anesthesia in Cats • Ketamine modulates theta and gamma oscillations • Ketamine for treatment-resistant unipolar depression • Ketamine in chronic pain management: an evidence-based review • Clinical experience with oral ketamine • Ketamine dependence • Effects of ketamine on sensory perception: evidence for a role of N-methyl-D-aspartate receptors. • The dissociative anaesthetics, ketamine and phencyclidine, selectively reduce excitation of central mammalian neurones by N-methyl-aspartate. • Ketamine reduces muscle pain, temporal summation, and referred pain in fibromyalgia patients • Refractory status epilepticus: response to ketamine • Ketamine for intravenous regional anesthesia. • Ketamine Pharmacology: An Update (Pharmacodynamics and Molecular Aspects, Recent Findings) • Postoperative pain: the effect of low-dose ketamine in addition to general anesthesia • Response of chronic neuropathic pain syndromes to ketamine: a preliminary study • Ketamine and midazolam neurotoxicity in the rabbit • Multiple mechanisms of ketamine blockade of N-methyl-D-aspartate receptors • Ketamine abuse • Ketamine: an update on the first twenty-five years of clinical experience • Comparison of morphine and morphine with ketamine for postoperative analgesia • Xylazine and xylazine-ketamine in dogs. • Psychiatric safety of ketamine in psychopharmacology research • Non-medical use of ketamine. • Ketamine: a paradigm shift for depression research and treatment • Antidepressant efficacy of ketamine in treatment-resistant major depression: a two-site randomized controlled trial • Ketamine anaesthesia in patients with intracranial pathology • Effects of morphine, lidocaine, ketamine, and morphine-lidocaine-ketamine drug combination on minimum alveolar concentration in dogs anesthetized with isoflurane • Ketamine-induced intracranial hypertension • Evaluation of xylazine and ketamine hydrochloride for anesthesia in horses. • Bioavailability, pharmacokinetics, and analgesic activity of ketamine in humans • 'Balanced analgesia'in the perioperative period: is there a place for ketamine? • Epidural ketamine for postoperative analgesia • Analgesic effects of ketamine administered in subdissociative doses • Ketamine for depression: where do we go from here? • Ketamine-induced loss of phenotype of fast-spiking interneurons is mediated by NADPH-oxidase • Ketamine as analgesic for total intravenous anaesthesia with propofol • Inhibition by ketamine of muscarinic acetylcholine receptor function • Midazolam and diazepam in ketamine anaesthesia • A randomized controlled trial of intranasal ketamine in major depressive disorder • Ketamine attenuates delirium after cardiac surgery with cardiopulmonary bypass • Propofol—Ketamine Technique • R-ketamine: a rapid-onset and sustained antidepressant without psychotomimetic side effects • Ketamine‐induced vesicopathy: a literature review • Ketamine as adjuvant analgesic to opioids: a quantitative and qualitative systematic review • Rapid-acting glutamatergic antidepressants: the path to ketamine and beyond • Reviewing the ketamine model for schizophrenia • Safety and efficacy of repeated-dose intravenous ketamine for treatment-resistant depression • Long-lasting hyperalgesia induced by fentanyl in rats preventive effect of ketamine • The interaction of ketamine with the opiate receptor • Ketamine anesthesia in electroconvulsive therapy. • Ketamine increases human motor cortex excitability to transcranial magnetic stimulation • Ketamine suppresses proinflammatory cytokine production in human whole blood in vitro • Clinical practice guideline for emergency department ketamine dissociative sedation: 2011 update • Ketamine-induced NMDA receptor hypofunction as a model of memory impairment and psychosis • Intramuscular ketamine for pediatric sedation in the emergency department: safety profile in 1,022 cases • Revising a dogma: ketamine for patients with neurological injury? • Ketamine and peripheral inflammation • NMDAR-independent, cAMP-dependent antidepressant actions of ketamine • Interactive effects of subanesthetic ketamine and haloperidol in healthy humans • Effects of intravenous ketamine on explicit and implicit measures of suicidality in treatment-resistant depression • Effects of ketamine on thought disorder, working memory, and semantic memory in healthy volunteers • Ketamine in cancer pain: an update. • Neuroprotective effect of ketamine administered after status epilepticus onset • Potential neurotoxicity of ketamine in the developing rat brain • Club drugs: methylenedioxymethamphetamine, flunitrazepam, ketamine hydrochloride, and gamma-hydroxybutyrate • Hemodynamic effects of ketamine in children with congenital heart disease. • Nefopam and ketamine comparably enhance postoperative analgesia • Ketamine inhibits endotoxin-induced shock in rats • Efficacy of prophylactic ketamine in preventing postoperative shivering • Cardiovascular changes in dogs given diazepam and diazepam-ketamine. • Association of ketamine-induced psychosis with focal activation of the prefrontal cortex in healthy volunteers. • Rapid and longer-term antidepressant effects of repeated ketamine infusions in treatment-resistant major depression • Neuronal mechanisms of ketamine-induced anesthesia • A blinded, randomized controlled trial to evaluate ketamine/propofol versus ketamine alone for procedural sedation in children • Effects of a ketamine metabolite on synaptic NMDAR function • Ketamine and epilepsy • Synaptic mechanisms underlying rapid antidepressant action of ketamine • Ketamine-induced neuroapoptosis in the fetal and neonatal rhesus macaque brain • Pharmacological properties of ketamine • Adverse events associated with ketamine for procedural sedation in adults • The semantics of ketamine • Use of ketamine in acute severe asthma • Cellular mechanisms underlying the antidepressant effects of ketamine: role of α-amino-3-hydroxy-5-methylisoxazole-4-propionic acid receptors • Ketamine attenuates the interleukin-6 response after cardiopulmonary bypass • Antidepressant effects of ketamine: mechanisms underlying fast-acting novel antidepressants • Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine • Epidural ketamine for control of postoperative pain. • Effects of ketamine infusion on halothane minimal alveolar concentration in horses. • Disruption of frontal–parietal communication by ketamine, propofol, and sevoflurane • Ketamine for caudal analgesia in children: comparison with caudal bupivacaine • Ketamine protects cultured neocortical neurons from hypoxic injury • Preemptive ketamine decreases postoperative narcotic requirements in patients undergoing abdominal surgery • Ketamine: 50 years of modulating the mind • Street ketamine'-associated bladder dysfunction: a report of ten cases • Ketamine as an adjuvant to opioids for cancer pain • Comparison of ketamine-induced thought disorder in healthy volunteers and thought disorder in schizophrenia • Ketamine: current applications in anesthesia, pain, and critical care • The effects of ketamine on cerebral circulation and metabolism in man • Ketamine potentiates analgesic effect of morphine in postoperative epidural pain control • Cognitive impairment after small-dose ketamine isomers in comparison to equianalgesic racemic ketamine in human volunteers • Plasma concentration profiles of ketamine and norketamine after administration of various ketamine preparations to healthy Japanese volunteers • Intravenous ketamine sedation of pediatric patients in the emergency department • Ketamine prevents ischemic neuronal injury • Interactive effects of subanesthetic ketamine and subhypnotic lorazepam in humans • The effect of ketamine on opioid-induced acute tolerance: can it explain reduction of opioid consumption with ketamine-opioid analgesic combinations? • Psychedelic effects of ketamine in healthy volunteers relationship to steady-state plasma concentrations • The role of ketamine in preventing fentanyl-induced hyperalgesia and subsequent acute morphine tolerance • Ketamine abusers presenting to the emergency department: a case series • Patterns of use and harms associated with non-medical ketamine use • The use of a ketamine-propofol combination during monitored anesthesia care • Intrathecal anesthesia with ketamine • Oral preanaesthetic medication for children: double-blind randomized study of a combination of midazolam and ketamine vs midazolam or ketamine alone • Postoperative analgesia with iv patient-controlled morphine: effect of adding ketamine • Preoperative ketamine improves postoperative analgesia after gynecologic laparoscopic surgery • Psychological effects of ketamine in healthy volunteers: phenomenological study • Ketamine gargle for attenuating postoperative sore throat • Altered prefrontal dopaminergic function in chronic recreational ketamine users • Comparison of ketamine and pethidine in experimental and postoperative pain • Intrathecal ketamine reduces morphine requirements in patients with terminal cancer pain • Prolonged exposure to ketamine increases neurodegeneration in the developing monkey brain • Dexmedetomidine-ketamine and propofol-ketamine combinations for anesthesia in spontaneously breathing pediatric patients undergoing cardiac catheterization • Small-dose ketamine enhances morphine-induced analgesia after outpatient surgery • Use and efficacy of low-dose ketamine in the management of acute postoperative pain: a review of current techniques and outcomes • Ketamine: new uses for an old drug? • Comparison of antidepressant and side effects in mice after intranasal administration of (R, S)-ketamine,(R)-ketamine, and (S)-ketamine • The destruction of the lower urinary tract by ketamine abuse: a new syndrome? • Acute and chronic effects of ketamine upon human memory: a review • Effectiveness and Safety of Ketamine for Unipolar Depression: a Systematic Review • Ketamine and phencyclidine: the good, the bad and the unexpected • Ketamine use in current clinical practice
  • Psilocybin and Depression • Effects of Hallucinogens and Other Drugs on Mood and Performance • Study in Healthy Recreational Polydrug Users to Measure the Abuse Potential of TC-5214 • Ketamine to Improve Recovery After Cesarean Delivery - Part 1 • The Pharmacokinetics of Ketamine in the Breast Milk of Lactating Women • Cardiovascular Safety After Continuous Ketamine Infusion • Low Dose Intravenous Ketamine in Treatment Resistant Depression Patients • Ketamine for Mood Disorders With Suicidal Ideation • Comparison of BIS Index Variations: Bolus Versus Infusion Ketamine, and Impact on the Anesthesia Gas Consumption • Neuropsychiatric and Cardiovascular Side Effects in Ketamine Analgesic Infusions • Role Of Ketamine in Treatment-Resistant Major Depressive Disorder And Its Effect on Suicidality • Ketamine for Refractory Chronic Migraine: a Pilot Study • Analgesia Effects of Intravenous Ketamine After Spinal Anesthesia for Non-elective Cesarean Section • Study to Assess the Effects of Intranasal Ketamine Along With rTMS for Patients With Treatment-resistant Major Depressive Disorder (TRD) • Preoperative Ketamine and Perioperative Depression • Intranasal (NAS) Ketamine for Cancer Pain • ED Treatment of Suicidal Patients With Ketamine Infusion • ECT With Ketamine Anesthesia vs High Intensity Ketamine With ECT Rescue for Treatment-Resistant Depression • Ketamine for Severe Adolescent Depression: Intermediate-term Safety and Efficacy • Continuous IntraVenous Infusion of Ketamine in Terminally Ill Cancer Patients • The Role of Ketamine as an Adjuvant Therapy for Children With Acute Status Asthmaticus • Comparison Between Low-dose Ketamine Infusion and Intravenous Morphine • Emergency Ketamine Treatment of Suicidal Ideation • Ketamine Reduces Tourniquet Pain In Patients Undergoing Lower Limb Surgery Under Spinal Anaesthesia • Ketamine for Depression and Suicide Risk • Intranasal Ketamine and Fracture Reduction in Pediatric Emergencies (KETAPED) • Pre-hospital Nebulized Ketamine for Pain • Inhaled Nebulised S(+)-Ketamine for Postoperative Analgesia • Pain Free Laceration Repairs Using Intra-nasal Ketamine • EEG Studies of Ketamine General Anesthesia • Ketamine vs Midazolam on Cognitive Function in Elderly in Elective Surgery Three-Months Postoperatively (ketaminvsMDZ) • Study to Find the Dose of Rapidly Administered Ketamine for Brief Painful Procedures in Children • Comparison of Treatment by IM Ketamine to IV Ketamine in Patients With Renal Colic • Ketamine and Postoperative Depressive Symptom-PASSION • Ketamine for Post-operative Analgesia in Hemorrhoidectomy • Analgo-Sedative Effects Of Oral, Or Nebulized Ketamine In Pre-schoolers Undergoing Elective Surgery. • Ketamine for Pain in the Emergency Department • Intravenous Ketamine Effects on Functional Neuroanatomy • Analgosedative adjuncT keTAmine Infusion iN Mechanically vENTilated ICU Patients • Intranasal Ketamine for Pediatric Procedural Sedation: a Feasibility Study • The Role of HNKs in the Antidepressant Effect of Ketamine • Action of Ketamine in Treatment-Resistant Depression • CYP2B6 Polymorphisms in Ketamine • Low-dose S-ketamine in Women With Prenatal Depression • Plasma Concentration of Ketamine and Norketamine . • Evaluation of Schemes of Administration of Intravenous Ketamine in Depression • Intravenous Sub-dissociative Dose Ketamine Injection Versus Infusion for Analgesia in the Emergency Department • Low-dose Ketamine and Postpartum Depression in Parturients With Prenatal Depression • Using a Low Dose of Ketamine vs. Active Placebo in Treating Severe Depression and Suicide • Efficacy And Tolerability Of Sub-Anesthetic Ketamine In Postpartum Depression • Spreading Depolarization and Ketamine Suppression • Intraoperative Ketamine for Patients Undergoing Total Joint Arthroplasty • Low-dose S-Ketamine and Postpartum Depression in Parturients With Prenatal Depression • Ketamine for Depression: An MRI Study • Ketamine Sickle Cell Disease • Intranasal Ketamine With Dexmedetomidine for the Treatment of Children With Autism Spectrum Disorder • Evaluating Ketamine and Psychological Sequelae • A Study to Decrease Suicidal Thinking Using Ketamine • Physiological and Cognitive Biomarkers for Ketamine's Antidepressant Effects • Perioperative Ketamine in Opioid-Tolerant Patients Undergoing Lumbar Spine Surgery • Effects of Low Dose Ketamine Given at Induction of Anesthesia on Postoperative Mood in Patients With Depressive Symptoms • Ultra-low Dose Oral Ketamine for Chronic Pain in the Primary Care Setting • Rapid Agitation Control With Ketamine in the Emergency Department • Ketamine Infusion Therapy for the Treatment of PTSD in Paramedics • Ketamine for Treatment-resistant Depression: A Multicentric Clinical Trial in Mexican Population • Adjuvant Low-dose Ketamine in Pediatric Sickle Cell Vaso-occlusive Crisis • Ketamine and Refractory Painful Care in a Palliative Unit • Study of Oral Ketamine Versus Placebo for Treating Depression in Patients Undergoing Treatment for Cancer • Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children With Non-operative Fractures • Ketamine Infusions for Major Depression Disorder • Comparison of CRP Levels, Neutrophil Count, and Clinical Outcomes of Low Dose Ketamine Between at Anesthesia Induction and at the End of Surgery in Patients Undergo Elective Laparotomy • Intravenous Ketamine in the Treatment of Obsessive-Compulsive Disorder • Low Dose Ketamine and Acute Pain Crisis • Effect of Ketamine in Depressive Symptoms of Elderly Patients With Visual Impairment. • Preoperative Ketamine Has no Preemptive Analgesic Effect in Patients Undergoing Colon Surgery. • Co-induction Ketamine-propofol: Effects on Laryngeal Mask Airway Insertion Conditions in Children • Intraoperative Ketamine Versus Saline in Depressed Patients Undergoing Anesthesia for Non-cardiac Surgery • Ketamine for Preventing Depression in Patients Undergoing Treatment for Pancreatic or Head and Neck Cancers • Low-Dose Intravenous Ketamine Bolus Versus Conventional Technique • Comparison of Effects of Intravenous Midazolam and Ketamine on Emergence Agitation • Ketamine Infusion in Neurologic Deficit • Perioperative Ketamine for Pain With Gastric Bypass • Ambulatory Infusions of Lidocaine and Ketamine for Management of Chronic Pain • The BIO-K Study: A Single-Arm, Open-Label, Biomarker Development Clinical Trial of Ketamine for Non-Psychotic Unipolar Major Depression and Bipolar I or II Depression. • Ketamine as an Adjunctive Therapy for Major Depression • Low Dose Ketamine for Management of Acute Severe Pain in the Emergency Department • Intranasal Ketamine for Suicidal Ideation in Veterans • Low-Dose Ketamine Infusion for Children With Sickle Cell Disease-Related Pain • Intranasal Versus Intravenous Ketamine for Procedural Sedation in Children • The Effect of Intravenous Ketamine on Non Suicidal Self Injuries. • Repeated Ketamine Infusions for Comorbid PTSD and MDD in Veterans • f Adding Ketamine to Propofol For Drug-induced Sleep Endoscopy in Adult Patients With Obstructive Sleep Apnea • Initiating Ketamine in Acutely Suicidal Patients in the Emergency Department • Comparison of Treatment by IN Ketamine to IV Morphine in Acute Pain • Ketamine Associated With Morphine PCA After Total Hip Arthroplasty • A Study to Evaluate Ketamine for the Treatment of Rett Syndrome • Ketamine Treatment for Pediatric-Refractory Obsessive-Compulsive Disorder (OCD) • Ketamine Interleaved With Electroconvulsive Therapy for Depression • Ketamine as an Adjuvant Therapy for Acute Vaso Occlusive Crisis in Pediatric Patients With Sickle Cell Disease • Subdissociative Dose Ketamine for Treatment of Acute Pain in Subjects With Chronic Pain • Ketamine Anesthesia for Improvement of Depression in ECT • Effects of TAK-063 on Preventing Ketamine-Induced Brain Activity Changes as Well as Psychotic-Like Symptoms in Healthy Male Adults • Intraoperative Low-dose Ketamine Infusion as the Main Analgesic in Burn Patients • Magnesium and Ketamine in Postoperative Analgesia • Sub-Dissociative Ketamine and Fentanyl to Treat Moderate to Severe Pain • Comparison of Ketamine and Etomidate During Rapid Sequence Intubation in Trauma Patients • Ketamine Effect on Isoflurane Anesthesia • The Pre-Emptive Administration Of Ketamine for Controlling Post-thoracotomy Pain • Ketamine as an Alternative Treatment to ECT in Major Depressive Disorder • Ketamine and Postoperative Cognitive Dysfunction • Ketamine Continuous Infusion on Opioid Consumption and Pain Management in Severe Burned Patients • Ketamine in the Treatment of Depression • The Effect of Ketamine Infusion on Lumbar Surgery • Biomarkers of Response to Ketamine in Depression: MRI and Blood Assays Before and After Open Label Intranasal Ketamine • Neuromodulation to Facilitate the Effect of Ketamine • Sevoflurane Associated With Oral Midazolam and Ketamine for Dental Sedation • Intranasal Ketamine For Pain Control In Patients With Sickle Cell Disease And Vaso-occlusive Episode (VOE) In The PED • Effect Of Ketamine Infusion In Patients With COPD Applied One Lung Ventilation • The Application of Ketamine for Sedation in Patients With Cardiac Arrest • A Pilot Clinical Trial of Oral Ketamine for Acute Pain Management After Amputation Surgery • Oral Ketamine Administration in Patients With Peripheral Neuropathic Pain • Reducing Ketamine-Induced Agitation, by Midazolam or Haloperidol Premedication After Adult Procedural Sedation • Study of Depression-Ketamine-Brain Function • Retrospective Evaluation of Ketamine Effectiveness for the Treatment of Acute Battlefield Related Pain • Methadone and Ketamine for Neuropathic Pain Treatment • Evaluating the Hemodynamic Effects of Ketamine Versus Etomidate During Rapid Sequence Intubation • Touchscreen-based Cognitive Tests in Healthy Volunteers • Naltrexone Plus Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder • Ketamine Infusion for Treatment-resistant Major Depressive Disorder • Ketamine-fentanyl VS Fentanyl for Analgosedation in SICU • Study of Intranasal Ketamine for Social Impairment in Autism Spectrum Disorder • The Effect of Ketamine in the Prevention of Hypoventilation in Patients Undergoing Deep Sedation Using Propofol and Fentanyl • A Trial of Intranasal Ketamine for the Treatment of Obsessive-Compulsive Disorder • Ketamine Infusion for Obsessive-Compulsive Disorder • Ketamine for Relapse Prevention in Recurrent Depressive Disorder • Ketamine's Effect Changes the Cortical Electrophysiological Activity Related to Semantic Affective Dimension of Pain • Ketamine Infusion for Pediatric Patients With Obstructive Sleep Apnea Syndrome (OSAS) After Tonsillectomy • Ketamine Infusion for Social Anxiety Disorder • Low Dose Ketamine Intra Nasal Traumatology • Effectiveness of Ketamine for Depression and Suicidal Ideation in the Emergency Department • RCT: Fentanyl Plus Ketamine Versus Fentanyl Alone for Acute Burn Pain • The Electroencephalogram and Clinical Effect of Ketamine • S Ketamine Use in Total Abdominal Hysterectomy • Ketamine for Depression Relapse Prevention Following ECT • Low Dose Ketamine Infusion for the Treatment of Resistant Depression • Ketamine Versus Midazolam for Prehospital Agitation • Ketamine for Acute Migraine in the Emergency Department • Influence of Morphine or Ketamine or Saline Applied During In-hospital Cardiopulmonary Resuscitation on Early Survival • Comparison of Ketamine-propofol Combinations • Low-Dose Ketamine in Children With ADNP Syndrome • Pharmacokinetics of Ketamine in Infants and Children • The Use of Ketamine and Dexmedetomidine in Intensive Care Sedation • Propofol-Ketamine vs Remifentanyl-Ketamine for Sedation in Pediatric Patients Undergoing Colonoscopy • Intraoperative Low-dose Ketamine Infusion for Patients With Obstructive Sleep Apnea • Ketamine Infusion for Sickle Cell Pain Crisis • Effectiveness of Ketamine in Malignant Neuropathic Pain Relief • Intranasal Ketamine for Procedural Sedation • Ketamine in the Treatment of Suicidal Depression • Open Label Ketamine Treatment for Major Depressive Disorder in Veterans • Ketamine in Chronic Kid's (KiCK) Pain • Intranasal Ketamine for Acute Traumatic Pain • Intravenous Ketamine and Postoperative Pain Following Cesarean Section. • Single Dose Administration of Ketamine 10, 20, 40 and 80 mg and 5 mg Solution for Infusion in 15 Healthy Subjects • Effectiveness of a Brief Cognitive and Behavioral Skills Program on Stage Transitions for Chronic Ketamine Abusers • Ketamine for Suicidality in Bipolar Depression • Ketamine Infusion Therapy for PTSD in Combat Veterans • A Comparison Study Between Ketamine Versus Tramadol for Pain Management After Major Upper Abdominal Surgery • Optimal Dosing of Ketamine for Procedural Sedation and Analgesia in Children • The Effect of Ketamine on Interleukin-6 Synthesis in Hepatic Resections Requiring Temporary Porto-arterial Occlusion • Pharmacokinetics of Low Dose Ketamine Infusion • Ketamine and Prolonged Exposure in PTSD • Prehospital Analgesia With Intra-Nasal Ketamine • Low-dose Ketamine vs Morphine for Vaso-occlusive Crisis in Sicklers • Comparison of Ketamine Combine Propofol vs Propofol Anesthesia in Schizophrenia Electroconvulsive Therapy • Ketamine Associated ACC GABA and Glutamate Change and Depression Remission: • Low Dose Perioperative Ketamine Infusion and it's Effect on Postoperative Pain Score, Sedation Score and Narcotic Consumption in Patients Undergoing Spine Surgery: A Prospective Randomized Double Blind Control Trial. • Ketamine in Refractory Convulsive Status Epilepticus • Analgesics in the Pre-hospital Setting: Implications on Hemorrhage Tolerance - Ketamine • Ketamine Versus Lidocaine Nebulization for Awake Fiberoptic Intubation • Efficacy and Safety of Continuous Infusion of Ketamine in Pediatric Intensive Care Unit (KISS Study) • Study of Ketamine for Depression in Cancer Patients Receiving Palliative Care • Oral Ketamine for Control of Chronic Pain in Children • Low Dose Peri-operative IV Ketamine for Chronic Post-surgery Pain Prevention • Treatment of Severe Mucositis Pain With Oral Ketamine Mouthwash • Intravenous Subdissociative-dose Ketamine Versus Morphine for Prehospital Analgesia • The Use of Ketamine as an Anaesthetic During Electroconvulsive Therapy • The Sustained Effects of Ketamine • The Effect of Ketamine on Postoperative Cognitive Dysfunction. • Ketamine Versus Propofol Effect on the Immune-mediatory Response for Abdominal Surgery • Ketamine Pharmacokinetics in Children Having Heart Surgery • Effects of Low-dose Ketamine as an Adjunct to Propofol-based Anesthesia for Electroconvulsive Therapy • Ketamine Tolerance in Children After Repeated Administrations During Radiotherapy Sessions • Comparison of Analgesic Effectiveness of Intravenous Ketamine and Fentanyl for Spinal Anesthesia is Sitting Position in Patients With Proximal Femur Fracture • Randomized Controlled Trial of Intranasal Ketamine vs. Intranasal Midazolam in Individuals With OCD • Ketamine Infusions for PTSD and Treatment-Resistant Depression • Pre-hospital Care With Intra-Nasal Ketamine for Transport (PRECINKT): A Pilot Study • Ketamine for the Treatment of Opioid Use Disorder and Depression • Effect of Intraoperative IV Ketamine on Postoperative Morphine Consumption During Intestinal Surgery • Ketamine and Changes of the Short Portable Mental Status Questionnaire • A Study to Investigate Evoked Potentials as Markers of Ketamine-induced Cortical Plasticity in Patients With Major Depressive Disorder • Cognitive Biases Under Ketamine • Racemic Ketamine Versus S-ketamine With Arterial Spin Labeling (ASL)-MRI in Healthy Volunteers • Ketamine Infusion for Acute Sickle Cell Crisis in the Emergency Department • Study Testing Ketamine Sublingual Wafer After Wisdom Tooth Extraction • A Comparison of the Effects of Ketamine and Remifentanil on Serum Cystatin-c Levels in CABG Surgery • The Effect of Ketamine on the Length of Hospital Stay of Patients Hospitalized With Suicidal Ideation. • Efficacy of Ketamine Infusion Compared With Traditional Anti-epileptic Agents in Refractory Status Epilepticus • The Impact of Ketamine on Postoperative Cognitive Dysfunction, Delirium, and Renal Dysfunction • Intranasal Ketamine and Midazolam Mixture for Procedural Sedation in Children With Mental Disabilities: • Analgesic Effects of Topical Ketamine Mouthwash in Patients Receiving Chemoradiation or Radiotherapy for Head & Neck Cancer • Ketamine in Borderline Personality Disorder • Impact of the Use of Ketamine in Laparoscopic Surgery. • Ketamine in Severe Traumatic Injury • SNAP VS BIS(OAA/S) Scale During a Sedation Regimen With and Without Ketamine • A Naturalistic Study of Ketamine for Treatment Resistant Mood Disorders • Ketamine as an Augmentation Strategy for Electroconvulsive Therapy (ECT) in Depression • Intranasal Ketamine as an Adjunct to Fentanyl for the Prehospital Treatment of Acute Traumatic Pain • Ketamine Anesthesia in Electroconvulsive Therapy • Immunomodulatory Properties of Ketamine in Sepsis • A Study of Brexpiprazole Plus Ketamine in Treatment-Resistant Depression (TRD) • Administration of Subanesthetic Dose of Ketamine and Electroconvulsive Treatment for Treatment Resistant Depression • The Effect of Ketamine on Attentiveness • Efficacy of Intra-articular Neostigmine Versus Ketamine for Postoperative Analgesia in Arthroscopic Knee Surgery • The Effect of Perioperative Ketamine on Acute and Chronic Pain After Major Back Surgery • Comparing Ketamine and Propofol Anesthesia for Electroconvulsive Therapy • The Effect of S-ketamine for Patients Undergoing Electroconvulsive Therapy (ECT) • Oral Ketamine in the Treatment of Depression and Anxiety in Patients With Cancer • Ketamine Co-induction for Patients With Major Depressive Disorder • To Test the Potential Efficacy of Repeated Intranasal Administration of Ketamine as a Treatment for PTSD • PET Imaging of mGLuR5 With Drug Challenge • An Open Prospective Trial of IV Ketamine in Suicidal Adolescents • Ketamine Prevent POCD • Ketamine Versus Morphine Change Pain Profile • Ketamine Effect After Laparoscopic Gastric Reduction: A Randomized, Double-Blinded, Placebo Controlled Study • The Effects of Low Dose Ketamine on Cardiovascular Function • Ketamine Patient-Controlled Analgesia for Acute Pain • Effect of Lithium Versus Placebo in Adults With Treatment-Resistant Depression Who Are Receiving Ketamine • Ketamine and Nitroprusside for Depression • Prospective Multicentre Study of the Use of Ketamine in the Treatment of Refractory Chronic Pain in the French CLCC • Prevention of Post Mastectomy With Intraoperative Ketamine • A Study to Assess the Electrophysiology, Safety, Tolerability, and Pharmacokinetics of SAGE-718 Using a Ketamine Challenge in Healthy Subjects • Ketamine Versus Haloperidol for Severe Agitation Outside the Hospital • Ketamine Versus Etomidate for Rapid Sequence Intubation • Ketamine in Adolescents With Treatment-Resistant Depression • Ketamine Versus Co-administration of Ketamine and Propofol for Procedural Sedation in a Pediatric Emergency Department • Ketamine for Treatment Resistant MDD • A Comparison of Intra-op Ketamine vs Placebo in Patients Having Spinal Fusion • Cognitive Behavioral Therapy in Prolonging the Antidepressant Effects of Intravenous Ketamine • Study of Ketamine as an Antidepressant in Major Depressive Disorder • Ketamine for Endoscopic Sedation in Outpatient Adult Endoscopy. • Ketamine to Prevent PPD After Cesarean • Ketamine and Glutamate After Brain Injury : a Microdialysis Study • Ketamine for Pain Relief in Bariatric Surgery • Impact of Sub-anesthetic Dose of Ketamine on Post Spinal Hypotension in Caesarean Delivery • Ketamine, Lidocaine and Combination for Postoperative Analgesia in Open Liver Resection • Investigation of the NMDA Antagonist Ketamine as a Treatment for Tinnitus • Extending Ketamine's Effects in OCD With Exposure and Response Prevention (EX/RP) • Respiratory Depression During an Analgosedation Combining Remifentanil and Ketamine in TCI for Oocyte Retrieval • Pupillary Dilation After Incremental Tetanic Stimulations Under Ketamine Sedation • Administration of Ketamine to Prevent the Post-operative Pain • A Randomized, Double-Blind Study of Placebo vs. Ketamine For Use During Dressing Changes in Critically Ill Burn Patients • Fentanyl vs. Low-Dose Ketamine for the Relief of Moderate to Severe Pain in Aeromedical Patients • Low Dose Ketamine (LDK) Versus Morphine for Acute Pain Control in the Emergency Department • Analgesic Effect of Ketamine in Patients Undergoing Hysteroscopic Endometrial Thermal Ablation Surgery • Ketamine Combination With Spinal Morphine for Post Thoracic Surgery Pain : A Randomized Control Study • Does Subacromial Injection With Glutamate Receptor Antagonist, Ketamine, Attenuate Pain in Rotator Cuff Tendinopathy? • Effects of Ketamine on Eye Movements, Perception and Brain Function • Effects of Ketamine in the Acute Phase of Suicidal Ideation • Sub-dissociative Dose Ketamine Dosing Study • Dexamethasone and Ketamine on Change of Postoperative Mood • Efficacy of Ketamine-Propofol for Short Surgical Procedures • Oral Ketamine as an Adjuvant to Opioids for Pain Treatment in Cancer Patients • Ketamine With Multilevel Paravertebral Block for Post Video-assisted Thoracic Surgery Pain • Escalating Ketamine Doses and Pre-emption • Use of Ketamine Associate With an Opioid for Sedation in ICU • Ketamine Infusion for Comorbid PTSD and Chronic Pain • The UTHealth Ketamine Project • Nasal Ketamine for Minor Procedures in Children • Dexmedetomidine and Ketamine in VATS Surgery • Dexmedetomidine-Ketamine Infusion in Breast Surgeries • Ketamine for Acute Pain Management After Trauma • Adding Ketamine to Low Dose Bupivacaine in Saddle Block for Perianal Surgery • Lidocaine-Ketamine for Management of Chronic Pain • Intranasal Ketamine for Late-Life Depression and Suicidal Ideation • Effect of Perioperative Low Dose Ketamine on Postoperative Recovery in Patients Undergoing Breast Cancer Surgery • IN Sub-Dissociative Ketamine vs IN Fentanyl • A Study of Sublingually Administered (S)-Ketamine Oral Solution in Healthy Participants • The Effect of Ketamine on Production of Inflammatory Markers in Post Operative Patients in Mulago Hospital • Ketamine Infusion and Hypoventilation • Continuation Ketamine in Major Depression • Low-dose Ketamine for Acute Pain in the Emergency Department • Comparison of Peritonsillar Infiltration of Tramadol Ketamine and Placebo on Pediatric Posttonsillectomy Pain • Ketamine vs. Placebo as Adjunctive Therapies for Severe Alcohol Withdrawal • Pilot Study of ORG 25935 Modulation of Ketamine-induced Behavioral and Cognitive Effects in Healthy Male Subjects • Intranasal Dexmedetomidine vs Midazolam-ketamine Combination for Premedication of Pediatric Patients • Ketamine in Patients Undergoing Anterior Cervical Discectomy and Fusion • Comparison Between Efficacy of Ketamine and Propofol Mixture With 1:6 Ratio and 1:4 Ratio for Endoscopic Retrograde Procedure Sedation • Study of Immunomodulation Using Naltrexone and Ketamine for COVID-19 • A Study to Investigate the Different Modes of (S) Ketamine Administration in Healthy Participants • A Randomized, Clinical Trial of Oral Midazolam Versus Oral Ketamine for Sedation During Laceration Repair. • Ketamine and Morphine Versus Morphine Alone for the Treatment of Acute Pain in the Emergency Department • Double-Blind Trial of Ketamine Therapy Plus or Minus Naltrexone in Treatment Resistant Depression (TRD) • Low Dose Ketamine as an Adjunct to Opiates for Acute Pain in the Emergency Department • Effects of Sevoflurane and Ketamine on QT in Electroconvulsive Therapy • Ketamine for Postoperative Pain in Bariatric Surgery • Nasal Administration of Sufentanil+Ketamine for Procedure-related Pain in Children • IN Ketamine vs IN Midazolam and Fentanyl for Laceration Repair • The Effect of Ketamine on the WAVCNS Index During General Anesthesia: A Feasibility Study • Ketamine Use in Electroconvulsive Therapy • Randomized Controlled Trial of Ketamine Infusion With Continuous Epidural Infusion for Treatment of Complex Regional Pain Syndrome • Ketamine: Comparison of IV Push vs. IV Drip • Topical Ketamine Analgesia in Children Undergoing Tonsillectomy: a Clinical and Serum Level Assays Study. • Effect of Ketamine on Laboratory-induced Stress in Healthy Subjects • Ketamine-Induced Brain Changes and Their Modulation by Lamotrigine • Ketamine vs Hydromorphone • Lamotrigine in Reducing Psychologic Side-Effect of Perioperative Ketamine • Efficacity, Safety and Cost of Intravenous Morphine Titration Alone or Combined to Ketamine • Ketamine as Adjunctive Analgesic With Bupivacaine in Paravertebral Analgesia for Breast Cancer Surgery • Dexmedetomidine Versus Midazolam Added to Ketamine in Pediatric Patients Undergoing Bone Marrow Aspiration and Biopsy • Ketamine-propofol Versus Ketamine Alone for Procedural Sedation in Adults • Ketamine as a Rapidly-Acting Antidepressant in Depressed Emergency Department Patients • Efficacy of Low Analgesic Doses of Ketamine Associated With Opioids in Refractory Cancer Pain Treatment • Does a Single Intravenous Dose of Ketamine Reduce the Need for Supplemental Opioids in Post-Cesarean Section Patients? • Ketamine Associated With Opioids in Refractory Cancer Pain Treatment • A Multimodal Neuroimaging Study of Brain Activation Patterns Under Ketamine • Local Ketamine Instillation for Postoperative Analgesia • Endogenous Opioid Modulation by Ketamine • Ketamine- Propofol Versus Pethidine- Propofol in ERCP • PVB vs Ketamine/Lidocaine in Rib Fracture Patients • Intraoperative Ketamine on Chronic Pain After Mastectomy • Trial of the Rapid Antisuicidal Effects of Intranasal Ketamine in Comorbid Depression and Alcohol Abuse • The Role of Ketamine in Preventing Cognitive Dysfunctions in Postoperative Period of Cardiac Surgery • The Effect of Ketamine on Immune Function and Prognosis in Patients Undergoing Colorectal Cancer Resection • Dexmedetomidine-ketamine in Femur Proximal Fracture Patients • Association of Intravenous Ketamine With Thoracic Epidural Analgesia: Effects on Pain and Respiratory Function Following Thoracotomy. • Efficacy of S(+)-Ketamine Administered as a Continuous Infusion for the Control of Postoperative Pain • Procedural Sedation Using Propofol Versus Midazolam/Ketamine in the Adult Emergency Department • Effect of Ketamine on Analgesia Post-Cardiac Surgery • Ketamine Improves Post-Thoracotomy Analgesia • Ketamine and Closed-Loop Anesthesia System • Ketamine Versus Electroconvulsive Therapy in Depression • Low Dose Ketamine Versus Morphine for Moderate to Severe Pain in the Emergency Department • Comparing Ketamine and Morphine in the Treatment of Acute Fracture Pain • Ketamine For Acute Treatment of Pain in Emergency Department • Intensive 7-day Treatment for PTSD Combining Ketamine With Exposure Therapy • The Effects of Ketamine on Respiratory Stimulation and Transpulmonary Pressures • Ketamine and Propofol for Upper Endoscopy • Ketamine as a Treatment for Post-Traumatic Stress Disorder (PTSD) • Geriatric Ketamine for Pain Management Study • Intra-nasal Ketamine for Analgesia in the Emergency Department • Pre-operative Pregabalin and Ketamine to Prevent Phantom Pain • Effects of Ketamine on Human Bladders and Its Possible Mechanisms • Effect of Single Dose Ketamine and Magnesium on Postoperative Pain in Patients Undergoing Bariatric Surgery • Subcutaneous Ketamine for Postoperative Pain Relief in Rwanda • Dexmedetomidine-Propofol and Ketamine-Propofol During Upper Gastrointestinal System Sedation • Effect of Ketamine Intranasal Spray in Treatment of Chronic Cluster Headache • Ketamine for Depression and Alcohol Dependence • Use of Ketamine to Enhance Electroconvulsive Therapy (ECT) in Depression • The Effect of Low Dose Intra-operative Ketamine on Closed-loop Controlled General Anesthesia • Ketamine / Propofol Admixture "Ketofol" at Induction in the Critically Ill Against Etomidate: KEEP PACE Trial • Ketamine Analgesia in Third Molar Surgery • Ketamine Versus Low Dose Thiopental for Induction of Anesthesia in Septic Shock • Alpha-Amino-3-Hydroxy-5-Methyl-4- Isoxazole Propionic Acid Receptor Components of the Anti-Depressant Ketamine Response • Substance Misuse To Psychosis for Ketamine (SToP-K) • Examining the Impact of Sirolimus on Ketamine's Antidepressant Effects • Ketamine for Thrombolysis in Acute Ischemic Stroke • Ketamine Versus Placebo for Treatment Resistant Major Depressive Disorder • Acute and Chronic Pain, Especially Neuropathic Pain, After Thoracotomy and Continuous Application of Ketamine. • A Study to Assess the Analgesic Properties of a Sublingual Wafer Formulation of Ketamine Following Third Molar Extraction • Effect of Subanesthetic Dose of Ketamine Combined With Propofol on Cognitive Function in Depressive Patients Undergoing Electroconvulsive Therapy • Ketamine Frequency Treatment for Major Depressive Disorder • A Comparison of Ketamine Infusion Versus Placebo in Opioid Tolerant and Opioid Naive Patients After Spinal Fusion • Low Doses of Ketamine and Postoperative Quality of Recovery • Epidural Levobupivacaine-sufentanil Versus Epidural Levobupivacaine and Intravenous Ketamine • CAP-Ketamine for Antidepressant Resistant PTSD • Effect of Ketamine+Propofol vs Remifentanyl+Propofol on Laryngeal Mask Insertion Conditions • Subanesthetic IV Bolus Ketamine in the Treatment of Acute Depression • Ketamine as a Rapid Treatment for Post-traumatic Stress Disorder (PTSD) • Retrobulbar Block Versus Ketamine Infusion for Post-enucleation Analgesia • Absolute Bioavailability and Nasopharyngeal Absorption of Intranasal Ketamine • A Proof-of-Concept Trial on the Effect of Ketamine on Fatigue • Ketamine and Magnesium in Post-operative Pain Control in Patients Treated With Opioids • Effect of Ketamine on Opioid-Induced Hyperalgesia • Ketamine v. Ketorolac for Management of Generalized Tension Type Headache • Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive Disorder • Ketamine-ketorolac Versus Fentanyl- Ketorolac I.M in Children During Bone Marrow Biopsy • Subcutaneous Wound Infiltration of Ketamine or Bupivacaine Pain Perception After Cesarean Section • Intranasal Ketamine in Treatment-Resistant Depression • Intra-nasal vs. Intra-venous Ketamine Administration • Is Analgesic Effect of Low Dose Ketamine-midazolam the Same as Morphine • Ketamine For Suicidal Ideation • The Analgesic Effect of Combined Treatment With Intranasal S-ketamine and Intranasal Midazolam • Ketamine for Treatment of MS Fatigue • Pilot Study on the Effects of Intravenous Ketamine on Acute Pain Crisis in Patients With Sickle Cell Disease • A Study of Ketamine in Patients With Treatment-resistant Depression • Exploring the Safety and Efficacy of Low-dose Ketamine Infusions for Pain Control in Acute Burn Injury • Pediatric Ketamine Study for Pain Management • Perioperative Lidocaine and Ketamine in Abdominal Surgery • Pilot Study of Ketamine in Adults With Obsessive-Compulsive Disorder (OCD) • Intranasal Ketamine for Anxiolysis in Pediatric Emergency Department Patients • Topical Ketamine Versus Caudal Ketamine for Postoperative Analgesia in Children Undergoing Inguinal Herniotomy • Lidocaine and Ketamine in Abdominal Surgery • The Effects of the Anesthetic Ketamine in Young Children Undergoing Procedural Sedation • Ketamine Treatment Effects on Synaptic Plasticity in Depression • The Effects of Ketamine and Methadone on Postoperative Pain for Laminectomy • Ketamine or Placebo in Patients With Major Depression and Advanced Cancer • Propofol Versus Ketamine for Moderate Procedural Sedation in the Emergency Department (ED) • Effects of Ketamine and Propofol in Otoacoustic Emissions (OAE) in Children • Comparison of N2O Inhalation and Ketamine in Pediatric PSA • Methadone and Ketamine for Spinal Surgery • Intranasal Ketamine Versus Intramuscular Ketamine for Procedural Sedation in Pediatric Patients • Intranasal Ketamine In the Treatment of Pediatric Bipolar Disorder • Topical Amitriptyline and Ketamine Cream in Treating Peripheral Neuropathy Caused by Chemotherapy in Cancer Patients • Pharmacokinetic Alterations During ECMO • miRNAs, Suicide, and Ketamine - Plasma Exosomal microRNAs as Novel Biomarkers for Suicidality and Treatment Outcome • Efficacy Study of Ketamine for Postoperative Pain in Opioid Dependent Patients • Understanding How Ketamine Brings About Rapid Improvement in OCD • The Use of Sedation Drugs in the Procedure of Administering Surfactant Without Intubation (LISA/MIST) • Sub-dissociative Ketamine for the Management of Acute Pediatric Pain • Ketamine Efficacy for Acute Severe Bronchospasm in ICU: MACANUDO Trial • Does Ketamine Attenuate Depression of Respiratory and Cardiac Functions • Positron Emission Tomography Assessment of Ketamine Binding of the Serotonin Transporter • IN Dexmedetomidine for Procedural Sedation in Pediatric Closed Reductions for Distal Forearm Fractures • Clinical Trial of the Use of Ketamine in Treatment Resistant Depression • Chart Review of Patients Undergoing Ketamine Infusions • Comparison of Low-dose Ketamine to Opioids in the Management of Acute Pain in Patients Presenting to the Emergency Department With Long Bone Fractures • Use of Ketamine vs Methohexital for Electroconvulsive Therapy (ECT) on Patient Recovery and Re-orientation Time • "THINK Trial: Treatment of Headache With IntraNasal Ketamine: A Randomized Controlled Trial Evaluating the Efficacy of Intranasal Ketamine Versus Standard Therapy in the Management of Primary Headache Syndromes in the Emergency Department" • Haemodynamic Stability of Ketamine/Propofol Admixture "Ketofol" in Patient Undergoing Endoscopic Retrograde Cholangio Pancreatography • Evaluation of the Effect of Ketamine on Remifentanil-induced Hyperalgesia • Optimization of IV Ketamine for Treatment Resistant Depression • Ketamine for the Rapid Treatment of Major Depressive Disorder and Alcohol Use Disorder • Preemptive Low-dose Epidural Ketamine for Preventing Chronic Post-thoracotomy Pain • Ketamine for Acute Painful Crisis in Sickle Cell Disease Patients • ELEKT-D: Electroconvulsive Therapy (ECT) vs. Ketamine in Patients With Treatment Resistant Depression (TRD) • Ketamine + Cognitive Training for Suicidality in the Medical Setting • Alcohol Withdrawal Syndrome Treated With Adjunctive Phenobarbital or Ketamine • Efficacy of Repeated Ketamine Infusions for Treatment-resistant Depression • Ketamine and fMRI for Neuropathic Pain • Ketamine Infusion for Adolescent Depression and Anxiety • Lidocaine-Ketamine Versus Ketamine for Induction of Anesthesia in Septic Shock Patients • Ketamine for Low Mood States in the ER • Sedation Methods During Cataract Surgery • Low Dose Ketamine Study on Opioid Tolerance and Hyperalgesia • Ketamine in Bariatric Surgery • Comparison of Propofol/Alfentanil With Propofol/Ketamine • intrathecaم Ketamine, Morphine and Both for Lower Abdominal Cancer Surgery Pain • Ketamine's Efficiency in the Treatment of Chronic Pain: Kynurenin Pathway • Nebulized Sub-dissociative Dose Ketamine for Treating Pain • Use of S+Ketamine During Target-Controlled Intravenous Anaesthesia After Abdominal Hysterectomy • Quelling of Excitotoxicity in Acute Stroke With Ketamine • Mechanism of Action Underlying Ketamine s Antidepressant Effects: The AMPA Throughput Theory in Patients With Treatment-Resistant Major Depression • Low Dose Ketamine Infusion for Postoperative Analgesia After Total Knee Arthroplasty • Hyperventilation Combined With Etomidate or Ketamine Anesthesia in ECT Treatment of Major Depression • A Comparison of Ketofol (Ketamine and Propofol Admixture) Versus Propofol as Induction Agents on Hemodynamic Parameters • Ketamine Versus Magnesium Sulfate in the Time and Awakening Quality of General Anesthesia. • Ketamine for Acute Suicidal Ideation in the Emergency Department: Randomized Controlled Trial • Delirium Prevention With Ketamine in Ear, Nose, and Throat (ENT) Patients • Ketamine for Major Depressive Disorder • Intranasal Midazolam Versus Intranasal Ketamine to Sedate Newborns for Intubation in Delivery Room • The Effects of Ketamine and Guanfacine on Working Memory in Healthy Subjects • Ketamine in Robot-assisted Thyroidectomy • Comparison of the Efficacy of Ketamine in Pediatric Patients With Idiopathic Scoliosis After Surgery • Effects of Perioperative Intravenous Lidocaine and Ketamine on Acute and Chronic Pain After Open Nephrectomy • The Effect of Different Dose of Ketamine With Low Dose Rocuronium in Children • Ketamine Versus Fentanyl for Induction of Anesthesia in Septic Shock • Ketamine/Propofol vs Ketamine Alone for Pediatric Fracture Reduction • Investigation of Antidepressant Efficacy of Oral Ketamine Treatment • THC and Ketamine Effects in Humans: Relation to Neural Oscillations and Psychosis • Prevention of Persistent Postsurgical Pain After Thoracotomy • Intranasal Ketamine as a Sedative for Venipuncture • Ketamine vs Propofol for Sedation During Pediatric Bronchoscopy • Ketamine and Neuropathic Pain • Ketamine Versus Magnesium Sulphate as Adjuvants for ESPB in Breast Cancer Surgery • Lidocaine as an Adjuvant for Ketamine in Induction of Anesthesia in Septic Shock Patients • A Comparison of the Sedation During Endoscopy in Children • Treatment of Suicidal Ideation With Intravenous Ketamine Infusion • The Effect of Anesthetic Agents Management on ECG Changes of Patients Who Were Operated Under RIVA • Bubiket Study: Ultrasound Guided Fascia Iliaca Nerve Block With Bupivacaine and Adjuvant Ketamine vs. Bupivacaine Alone • TIMBER Psychotherapy and Ketamine Single Infusion in Chronic PTSD • Intra-operative Ketamine Infusions in Opioid-dependent Patients With Chronic Lower Back Pain • Multiple Dose Pharmacokinetics of Intranasal Ketamine • Ketamine Versus Etomidate for Procedural Sedation for Pediatric Orthopedic Reductions • Etomidate Versus Ketamine for Emergency Endotracheal Intubation: a Prospective Randomized Clinical Trial • Combined Ketamine/Propofol for Emergency Department Procedural Sedation • Post-op Ketamine Study • Examining The Effect Of Ketamine On Glutamate/Glutamine Cycling • Perioperative Opioid-induced Hyperalgesia and Its Prevention With Ketamine and Methadone • Effects of TS-134 on Ketamine-induced BOLD Signals in Healthy Subjects • Intraoperative Ketamine and Magnesium Therapy for Control of Postoperative Pain After a Liposuction and Lipoabdominoplasty • Assessing the Effects of a Nasal Corticosteroid on PMI-150 (Intranasal Ketamine) • Comparison of Oral Morphine Versus Nasal Ketamine Spray With Chitosan in Cancer Pain Outpatients • Effectiveness of Atropine and Glycopyrrolate to Reduce Hyper Salivation With Ketamine Sedation • Ketamine in Colorectal Surgery • Nebulized Sub-dissociative Dose Ketamine at Three Different Dosing Regimens for Treating Acute Pain in the Pediatric ED • Ketamine for Treatment Resistant Late-Life Depression • Effect of Ketamine on Fatigue Following Cancer Therapy • Double Blind Placebo Controlled Study of Outpatient Intravenous Ketamine for the Treatment of CRPS • Dexmedetomidine,Ketamine and Their Combination to Bupivicaine on Thoracic Epidural Analgesia • Dose-response of Ketamine in Patient Controlled Analgesia in Orthopaedic Surgery Patients • The Effect of Minocycline on Relapse After Successful Intravenous Ketamine/Minocycline-induced Symptoms Response in Subjects With Depression • Ketamine and Hydromorphone for Patient Controlled Pain Relief in Children's Mucositis • Antipruritic Effect of Topical Ketamine, Amitriptyline, and Lidocaine • Randomized Clinical Trial of Propofol, 1:1 and 4:1 Combination of Propofol and Ketamine for Procedural Sedation • A Clinical Trial of Oral Midazolam Plus Oral Ketamine for Sedation During Laceration Repair • Effect of Ketamine on Postoperative Clinical Outcomes • Ketamine Versus Dexmedetomidine With Local Anesthetic in TAP Block • Ketamine Versus Etomidate During Rapid Sequence Intubation: Consequences on Hospital Morbidity • Effect of Ketamine Added to Intravenous Patient-controlled Analgesia on Postoperative Pain, Nausea and Vomiting in Patients Undergoing Lumbar Spinal Surgery • Reversal of Ketamine Pharmacodynamic Effects With Naloxone • Ketamine In Thoracic Surgery (KITS) Trial • Trial of Ketamine and Lithium Therapy in Bipolar Depression • Intrathecal Ketamine, Dexmedetomidine and Both With Bupivacaine for Postoperative Abdominal Cancer Surgery Pain • Evaluation of the Initial Prescription of Ketamine and Milnacipran for Depression in Palliative Care • Ketamine and Propofol Combination Versus Propofol for Upper Gastrointestinal Endoscopy • Efficacy of Ketamine in Children With Severe Brain Injury for Brain Cell Protection • The CHECK Trial: A Comparison of Headache Treatment in the Emergency Department: Compazine Versus Ketamine • Sub-dissociative Intranasal Ketamine for Pediatric Sickle Cell Pain Crises • The Preemptive Analgetic Potency of Low Dose S-Ketamine • D-cycloserine for Relapse Prevention Following Intravenous Ketamine in Treatment-resistant Depression • Systemic Ketamine for the Improvement of Post-Operative Analgesia at the Alcohol-Dependent Patient • Use of a Multimedia Presentation for Informed Consent • Effect of Ketamine Addition to Lidocaine in Rhinoplasty • Ketamine Challenge Study With JNJ-40411813 • Safety and Efficacy of Repeated Doses of PMI-150 (Intranasal Ketamine) in Acute Post-operative Pain Following Orthopedic Surgery • Single-dose Ketamine for the Reduction of Pain and Depression in the Emergency Department • Biomarkers of Fast Acting Therapies in Major Depression • A Study To Examine The Effects Of PF-04958242 On Ketamine-Induced Cognitive Impairment In Healthy Volunteers • Ketamine Trial for the Treatment of Depression • Pain Reduction With Intranasal Medications for Extremity Injuries • Treatment Resistant Depression (Pilot) • Ketamine as an Anaesthetic Agent in Electroconvulsive Therapy (ECT) • Intranasal Ketamine Versus Intranasal Fentanyl • Low Dose Ketamine VR Analgesia During Burn Care Procedure • The Impact of Ketamine on the Reward Circuitry of Suicidal Patients • Intramuscular Ketamine Versus Aripiprazole and Escitalopram in the Treatment of Resistant Depression • Study on the Use of Low Dose Ketamine After Gastric Bypass and Gastrectomy • Intranasal Dexmedetomidine Plus Ketamine for Procedural Sedation • Dexmedetomidine and Ketamine in MRI • Ketamine Plus Lithium in Treatment-Resistant Depression • Evaluation of a New Protocol for Adult Procedural Sedation With Ketamine-propofol in a 1 on 4 Ratio • Analgesic Efficacy of Intravenous Lidocaine and/or Ketamine • IN Ketamine Vs IN Midazolam and Fentanyl for Abscess I&D • Dexmedetomidine, Ketamine and Dexmetedomidine-Ketamine Combination for Control of Shivering During Regional Anaethesia • Comparing Clinical Outcomes Between Ketamine-midazolam and Morphine-midazolam for Continous Sedation in ICU Patients. • Ketamine Long Therm Follow Up Study • Intravenous Ketamine for Pain Control During First Trimester Surgical Abortion • Efficacy of Ketamine for Improvement in Postoperative Pain Control After Spinal Fusion for Idiopathic Scoliosis • Estimate the Efficiency of the Association of an Injection of Ketamine and the Venlafaxine in the Severe Major Depressive Disorder for Six Weeks • Effect of Wound Infiltration by Ketamine Versus Dexmedetomidine Added to Bupivacaine on Surgical Stress • Levetiracetam, Lacosamide and Ketamine as Adjunctive Treatment of Refractory Status Epilepticus • Low Dose Ketamine as an Adjunct to Fentanyl in Outpatient Tonsillectomy • Combination Ketamine and Propofol vs Propofol for Emergency Department Sedation: A Prospective Randomized Trial • Ketamine and Postoperative Analgesia in Children • Ketamine for Reduction of Alcoholic Relapse • Effect of Ketamine (Ketalar) on Intracranial Pressure • Postoperative Analgesia by Epidural vs IV Ketamine Concurrent With Caudal Anesthesia in Pediatric Orthopedic Surgery • The Effect of Ketamine on Mechanises Underlying Suicidal Ideation and Drug-resistant Major Depression • Ketamine Alcohol (in Treatment-Resistant Depression) • Effect of Ketamine vs. Active Placebo on Suicidal Ideation in Depressed Inpatients With Major Depressive Disorder or Bipolar Depression. • Ketamine in Post-operative Dental Pain and Recovery • Ketamine Sedation in Mechanically Ventilated Patients • Laryngeal Mask Insertion Conditions And Hemodynamic Effects • Remifentanil Requirement for Acceptable Intubating Condition • KETOR: Effects of Peri Operative Administration of Ketamine on Long Term Post Thoracotomy Pain • A Study of Ketamine as an Antidepressant • Comparison of Outcomes During MRI Sedation With Midazolam-dexmedetomidine Versus Ketamine-dexmedetomidine • The Interest of the Xylocaine® and Ketamine on the Management of Acute and Chronic Ain After Colectomy by Laparoscopy • Double-Blind, Placebo-Controlled Trial of Ketamine Therapy in Treatment-Resistant Depression (TRD) • Effects of Wound Infiltration With Ketamine Versus Dexmedetomidine Added to Bupivacaine on Cytokines • Intranasal Ketamine for Procedural Sedation in Pediatric Laceration Repair • Determination of Drug Interactions of Certain Nasal Medications With Intranasal Ketamine • Research Study for Major Depressive Disorder: Investigation of Glutamate Medications • The Effect of Intraoperative Ketamine on Opioid Consumption and Pain After Spine Surgery in Opioid-dependent Patients • Remifentanil Plus Ketamine for Dynamic Flexible Bronchoscopy • Intravenous Ketamine Plus Neurocognitive Training for Depression • Sedation During Pediatric Diagnostic Gastrointestinal Endoscopy Gastrointestinal Endoscopy • Network Dysfunction, Schizophrenia and Pharmacological Magnetic Resonance Imaging (phMRI) • Premedication With Nebulized Ketamine,Dexmedetomidine Versus Midazolam in Oncologic Preschool Children • Comparison the Effects of 3 Different Intraarticular Ketamine Doses on Postoperative Pain. • Intranasal Sedation With Dexmedetomidine and Ketamine in Pediatric Dentistry (NASO II) • Effect of Perioperative i.v. Low-dose S(+) Ketamine • Effect of the Addition of Ketamine to Sevoflurane Anesthesia in Electroconvulsive Therapy • The Effect Of Ultrasound-guided Modified Pectoral Nerves Block Versus Ketamine Plus Magnesium Infusion On Analgesic Profile In Breast Cancer Surgeries • The Prevention of Delirium and Complications Associated With Surgical Treatments Multi Center Clinical Trial • Sedation During Spinal Anesthesia • Baclofen-Amitriptyline Hydrochloride-Ketamine Gel in Treating Peripheral Neuropathy Caused by Chemotherapy in Patients With Cancer • Comparison of Propofol, Propofol-remifentanil and Propofol-ketamine Anesthesia During Electroconvulsive Therapy • Comparing Efficacy Preoperative Nebulized: Ketamine , Mgspo4 ,and Lidocaine In Attenuating Endotracheal Sore Throat • Ketamine Infusion Therapy for the Management of Acute Pain in Adult Rib Fracture Patients • Analgesic Effect in Children of Low-Dose Ketamine for Mucositis Treated by Patient-Controlled Analgesia With Morphine • OBSERVATIONAL STUDY OF THE MANAGEMENT OF PATIENTS WITH CHRONIC PAIN • Peri-Operative Lidocane, Ketamine, or Lidocane and Ketamine Combination, Infusion for Patients Undergoing Spine Surgery • Lidocaine and Ketamine Versus Standard Care on Acute and Chronic Pain • Ketamine Versus Fentanyl as an Adjunct to Propofol-Assisted Emergency Department Procedural Sedation • The Use of Ketamine as Rescue Analgesia in the Recovery Room Following Opioid Administration. A Double-blind Randomised Trial in Postoperative Patients • ESKETamine for FIBromyalgia Treatment • Ketamine and Scopolamine Infusions for Treatment-resistant Major Depressive Disorder • A Comparison of Etomidate and Ketamine for Anesthesia Induction in Coronary Artery Bypass Graft Surgery • Ondansetron Reduce Vomiting Associated With Ketamine PSA • A Study to Assess Electrophysiology, Safety, Tolerability, and Pharmacokinetics of Multiple Doses of SAGE-718 Using Ketamine Challenge in Healthy Subjects • Biomarker Assessment of Glutamatergic Target Engagement • The Effect of Peritonsillar Infiltration of Ketamine and Dexamethasone for Postoperative Pain Relief in Children Following Adenotonsillectomy • Pain Relief for Submucosal Resection of Nasal Septum in Adults Does Ketamine Have a Pre-Emptive Effect? • Effects of IV Administration of Ketamine on the Analgesia Nociception Index (ANI) Measured With the PhysioDoloris • Intra-op Lidocaine and Ketamine Effect on Postoperative Bowel Function • Oral Dexmedetomidine for Parental Separation in Pediatrics Undergoing Adenotonsillectomy • Safety and Efficacy of PMI-150 (Intranasal Ketamine) for the Treatment of Breakthrough Pain in Cancer Patients • Effects Of PF-02545920 On Ketamine-Induced Abnormal Prefrontal Brain Response To Associative Learning In Healthy Subjects • Proper Dosage of Ketamine in Intravenous Regional Anesthesia • Use of Ketamine Prior to Cardiopulmonary Bypass in Children • Premedication for Less Invasive Surfactant Administration • The CHECK Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine • Crossover Study to Evaluate the Abuse Potential of Intranasal Esketamine Compared to Racemic Intravenous Ketamine in Nondependent, Recreational Drug Users • An Exploratory Trial of Ketamine for the Treatment of Rett Syndrome • Ketamine on Acute Pain in Females and Males • Lamotrigine for Ketamine Dependence Trial • Inhaled Nitrous Oxide for the Prevention of Emergence Reaction During Ketamine Administration in Adults, a Pilot Study • Rapid Antidepressant Effects of Ketamine in Major Depression • Comparison of Efficacy of Anesthesia Administered by Endoscopist or Anesthesiologist on Colonoscopy • Sedation of Morbidly Obese for Balloon Insertion • Treatment Study of Bipolar Depression • Evaluation of the Analgesic Effect of Midazolam and Ketamine as an Additive to Intrathecal Bupivacaine in Patients Undergoing Cesarean Section • Prevention of N-methyl-D-aspartate (NMDA) Antagonist-induced Psychosis in Kids • A Study of HR071603(Ketamine Nasal Spray) in Healthy Subjects • Parallel Effects of Schizophrenia and N-methyl-D-aspartate (NMDA) Antagonism • Study of Ketamine Administered Intravenously and by Sublingual Wafer • Safety and Efficacy of Intranasal Ketamine for the Treatment of Postoperative Dental Pain • Analgesia During Pediatric Digestive Endoscopy: a Comparison of Two Protocols for Procedural Sedation • Percutaneous Ketamine Versus Lidocaine or Placebo, for Post-Surgery Analgesia, in Patients Undergoing Laparoscopic Partial Lung Resection • Frequent Ketamine Use and Gastrointestinal, Liver and Biliary Sequelae • Evaluation of Ketamine and Multi-modal Analgesics • Assessment of Ketamine and Propofol Sedation During LISA Method (Less Invasive Surfactant Administration) • N-methyl-D-aspartate Antagonist (Ketamine) Augmentation of Electroconvulsive Treatment for Severe Major Depression • Dexmedetomidine Sedation With Third Molar Surgery • NRX100 vs. Placebo for Rapid Stabilization of Acute Suicidal Ideation and Behavior in Bipolar Depression • Effects of Perioperative Systemic Ketamine on Development of Long-term Neuropathic Pain After Thoracotomy • Effect of a Topical Ketamine on Acute and Chronic Pain, Dose Finding • Efficacy of Ketamine Added to Local Anesthetic in Modified Pectoral Block for Management of Postoperative Pain • Midazolam and Ketamine Effect Administered Through the Nose for Sedation of Children for Dental Treatment • Percutaneous Ketamine Versus Lidocaine for Mid-Sternotomy • Opioid vs. Opioid-free Anesthesia for Hip Arthroscopy • Effects of Ketamine and Risperidone on Cognition • Pain Medicine for Wound Care Procedures • Combined Intra-articular Shoulder Injection and Stellate Ganglion Block in Chronic Post-mastectomy Shoulder Pain • The Efficacy of Midazolam & Ketamine Versus Midazolam & Fentanyl for Sedation in Ambulatory Colonoscopies • Effect of Ketalar to Prevent Postoperative Chronic Pain After Mastectomy • A Study of LY2979165 and LY2140023 in Healthy Volunteers • The Anti-inflammatory Effect of Anesthetics in Abdominal Surgery • The Effect of Brief Potent Glutamatergic Modulation on Cocaine Dependence • Sedation for Upper Gastrointestinal Endoscopy in Pediatric Patients • NMDA Antagonists in Bipolar Depression • Ketofol vs Propofol for Emergency Department Procedural Sedation and Analgesia • Randomised Trial Ketiapine Olanzapine Fast Sedation Agitated Patients Emergency Ward • The Effect of Gabapentin, Ketamine and Dexamethasone on Pain and Opioid Requirements After Hip Surgery • Ketamine Hydrochloride and Best Pain Management in Treating Cancer Patients With Neuropathic Pain • A Study to Assess the Electrophysiology, Safety, Tolerability, Pharmacokinetics and Pharmacodynamics Response Using Magnetic Resonance Imaging of SAGE-718 Using a Ketamine Challenge in Healthy Subjects • A Study of Different Oral Thin Film (S)-Ketamine Formulations for Sublingual Administration in Healthy Participants • Comparison of Different Ratio of Ketofol (6:1 vs. 4:1) for Sedation in Endoscopic Retrograde Cholangiopancreatography (ERCP) • Adjunctive Atropine During Ketamine Sedation • Glutamatergic Modulation of Cocaine-related Deficits • EEG Characteristics in ECT • Pain Alleviation of Forearm Fractures • Comparison of Methods to Facilitate Rapid Sequence Intubation • Glutamatergic Modulation of Disordered Alcohol Use • Cognitive Therapy to Sustain the Antidepressant Effects of Intravenous Ketamine in Treatment-resistant Depression • Cognitive Recovery After Electroconvulsive Therapy and General Anesthesia • The Effects AZD8529 on Ketamine-induced Impairment of Working Memory in Healthy Volunteers • Effects of Ketamine On Precipitated Opioid Withdrawal Under General Anaesthesia • Opiate Suicide Study in Patients With Major Depression • Remifentanil Use in Pediatric Rigid Bronchoscopy • Single Bolus Dose of Ketodex Versus Ketofol For Prevention Of Emergence Agitation In Adults Undergoing Nasal Surgeries • Sedation MRI - Propofol Versus Propofol-Ketamin in Children • Transversus Abdominis Plane Block In Children • Comparing Effect of Adding Ketamine Versus Dexmedetomidine to Bupivacaine in Pec 11 Modified Block on Postoperative Pain Control in Patients Undergoing Breast Surgery • Neuropathic Pain Caused by Radiation Therapy • Sevoflurane Induced Emergence Agitation • A Study of Human Multi-Sensory Integration • Pediatric Ilioinguinal / Iliohyogogastric Nerve Block • Polyamine-free Diet to Prevent Post Surgery Hyperalgesia • Ketamine/Placebo Family History Positive Study • Infra-orbital Nerve Block for Post Operative Analgesia in Children Undergoing Cleft Lip Surgery. • A Blinded, Four-Way Crossover in Healthy Subjects to Assess EEG After Administration of Ketamine, Placebo and AZD6765 • Propofol-fentanyl-ketamine (PFK) Combination Versus General Anesthesia Using Propofol and Fentanyl in Patients Undergoing Endoscopic Procedures. • The Effect of Ondansetron During Intramuscular Ketamine Use in Children: A Trial in Emergency Department • Ketamine Compared to Propofol for Pediatric GI Endoscopy • Efficacy of Dexamethasone for Prevent Vomiting in Leukemic Children Who Receive Intrathecal Chemotherapy • A Study of the Efficacy and Safety of Amitriptyline/Ketamine Topical Cream in Patients With Diabetic Peripheral Neuropathy • Neurobiology of Suicide • Lidocaine as Local Anesthetics in Children Under Ketamine Sedation • Behavioral and Electrophysiological Effects of Ketamine in Treatment-Resistant Depression • Compare the Effect of Propofol vs. "Ketofol" on Hemodynamic Stability During Induction of General Anesthesia • Alternative Sedation During Bronchoscopy • Stanford Reward Circuits of the Brain Study • Sedation and Analgesia Using PFK Versus General Anesthesia in Urological Procedures • Spontaneous and Oxytocin-induced Contractility After Exposure to Intravenous Anesthetic Agents: an In-vitro Study in Human Myometrium • EEG Studies of Sevoflurane-Induced General Anesthesia • Blood Levels of Ketamine in Patients Using Topical Application of 10% Ketamine Gel for Neuropathic Pain • Comparison of Opioid Based and Opioid Free Anaesthesia in Transsphenoidal Surgery • Study of NMDA Antagonists and Neuropathic Pain • Anticholinergic Premedication Induced Fever in Pediatric Ambulatory Anesthesia With Ketamine • The Effect of Opioid Free Anesthesia in Bariatric Surgeries • Post-operative Pain Relief in Laparoscopic Cholecystectomy • The Effect of Preoperative Ketamine on the Emergence Characteristics in Children Undergoing Entropion Surgery • Crossover Study to Evaluate the PK Effects of Two Different Wafer Administration Protocols. • Neurophysiology and Pharmacology of Cough Reflex Hypersensitivity • The Effect of Glutamatergic Modulation on Cocaine Self-administration • Nicotinic Modulation of Schizophrenia-like Information Processing Deficits in Healthy Subjects • Effects of Propofol and Ketofol on Core Body Temperature in MRI • Lornoxicam With Low Dose Ketamine Versus Pethidine to Control Pain of Acute Renal Colic • Conscious Sedation Efficacy of the MKO Melt (Midazolam, Ketamine, Ondansetron) • Evaluation of Closed-loop TIVA Propofol, Sufentanil and Ketamine Guided by BIS Monitor • Is it Possible to Replace Fentanyl in Anesthesia for Minor Procedures? • Anesthesia for Retinopathy of Prematurity • Facilitating the Behavioral Treatment of Cannabis Use Disorder • Changes in Striatal [11C]ORM-13070 Binding Elicited by Changing Levels of Endogenous Noradrenaline • Assessment of Abuse Potential of Rapastinel in Humans • Diabetic Neuropathy Topical Treatment • Characterizing Clinical and Pharmacological Neuroimaging Biomarkers • Three-level Injection Paravertebral Block vs General Anesthesia in Mastectomy • Memantine Augmentation in Treatment-Resistant Adults With Obsessive-Compulsive Disorder • Hyperalgesia and NMDA Receptor Antagonist • Prospective Study of Induction Medications Used in the Trauma RSI • The Effects of Optimizing Post-operative Pain Management With Multi Modal Analgesia on Immune Suppression and Oncologic Outcome in Patients Undergoing Laparoscopic Colorectal Surgery • Anesthesia and Functional Connectivity: An Analysis of fMRI Changes • A Study to Evaluate Central Nervous System (CNS) Pharmacodynamic Activity of TAK-653 in Healthy Participants Using Transcranial Magnetic Stimulation (TMS) • Study of Comparison of the Effectiveness of Three Diagrams for Sedation in Spinal Anesthesia • Memory Modulation by Pain During Anesthesia • Imaging SV2A in Mood Disorders • Assessment of Effect of Rapastinel on Driving Performance • Proof of Concept Study Evaluating the Efficacy and Safety of MIJ821 in Patients With Treatment-resistant Depression • A Comparison of EpiCept™ NP-1 Topical Cream vs. Oral Gabapentin in Postherpetic Neuralgia (PHN) • The Role of Brief Potent Glutamatergic Modulation in Addressing Problem Drinking • Perioperative Electroacupuncture on Postoperative Analgesia in Prostatectomy • Acute Pain Management in Patients on Opioid Replacement Therapy • Comparison of Transversus Abdominis Plane Block and Ilioinguinal / Iliohypogastric Nerve Block • Anesthetics in Rhytidoplasty - A Comparison Study • KETODEX for Emergence Delirium in Children Undergoing Outpatient Strabismus Surgery • Facilitating Rapid Naltrexone Initiation • The Effects of Dexmedetomidine on Early Stage Renal Functions in Pediatric Patients • Multimodal Analgesia in Cardiac Surgery (Pilot Study) • Effect of Intraoperative Nefopam on Acute Pain After Remifentanil Based Anesthesia • Narcotic Free TIVA (Total Intravenous Anesthesia) and the Incidence of Unacceptable Movements Under General Anesthesia During ACDF (Anterior Cervical Discectomy and Fusion) Surgery • Interscalene Nerve Block vs. Sedation for Shoulder Dislocation Reduction • Abdominoplasty Under Spinal Anesthesia • Intravenous Lidocaine for Perioperative and Postoperative Analgesia • Postpartum Perineal Pain After Obstetric Anal Sphincter Injuries • Recovery After Total Intravenous Anesthesia With Ketofol Versus Mixture of Ketofol and Lidocaine for Short Pediatric Surgery • Baden Prevention and Reduction of Incidence of Postoperative Delirium Trial • Sequential Therapy for the Treatment of Severe Bipolar Depression. • Glutamatergic Modulation to Facilitate Naltrexone Initiation in Opioid Dependence • Opioid Versus Non-opioid Anesthesia for Ambulatory Surgery in Children • Sedation Versus Protective Stabilization for Pediatric Dental Treatment • Efficacy of Moderate Sedation for Dental Treatment of Young Children • A Study Of The Effectiveness Of Wafermine Alone And In Combination With Opioids In Subjects Undergoing Bunionectomy • The Neural Mechanisms of Anesthesia and Human Consciousness (Part 6) • ACL Repair and Multimodal Analgesia • Different Modalities of Analgesia in Open Heart Surgeries in Mansoura University • Glutamatergic Modulation to Facilitate the Behavioral Treatment of Cocaine Use Disorders • N-acetylcysteine and NMDA Antagonist Interactions • Multimodal Analgesia in Major Abdominal Pediatric Cancer Surgeries • Study Where Pharmaco Magnetic Resonance Imaging (MRI) Effects of AZD6765 Will be Compared to Placebo in Depressive Male and Female Subjects • Opioid Based Anesthesia vs Opioid Free Anesthesia in Cleft Lip, Palate, Alveolus Surgery. • Comparative Effects of Dexmedetomidine and Ketofol for Sedation in Patients Undergoing Trans-esophageal Echocardiography • A Pilot Study: a Non-opioid Technique for Postoperative Adenoidectomy Pain Relief in Pediatric Patients • Ketofol Versus Fentofol for Procedural Sedation in the Pediatric Emergency Department • Sensory Examination and Pharmacological Modulation of Oral Hyperexcitability in Patients With Atypical Odontalgia and Matched Healthy Controls • The Effects of Sedatives on Tobacco Use Disorder • OFA - Opioid Free Anesthesia • Avoiding Neuromuscular Blockers to Reduce Complications • Dyphenhidramine Effect on Prevention of Sevoflurane Induced Post Anesthesia Agitation in Pediatric • Clinical Trial to Examine Individual Pain Tolerance in the Use of Two Anesthetic Techniques to Perform Saturation Prostate Biopsy • A Study to Assess the pharmacoMRI Effects of AUT00206 in Healthy Males • Pediatric Laser Acupuncture and Renal Biopsy • Anesthetics and Auditory, Visceral, and Heat Evoked Potentials • Preventing Pain After Heart Surgery • Pre-Emptive Analgesia in Ano-Rectal Surgery • The Incidence and Nature of Adverse Events During Pediatric Sedation for MRI/CT in One Korean University Hospital: Retrospective Study • Analgesic Efficacy of Ropivacaine Alone or in Combination With Adjuvants on Post-operative Analgesia Following Video-Assisted Thoracoscopic Surgery. • Prevention of Complications of Eye Surgery • Opioid Free Anesthesia and Continuous Post-operative Pulse Oximetry Monitoring in the Obese Patient • Sedation During Muscle Biopsy in Patients With Duchenne Muscular Dystrophy • Postoperative Analgesia in Patients With Microvascular Decompression • Methadone Versus Morphine for Orthopedic Surgery Patients • Anesthetic Techniques in EP Patients • Neurocognitive Features of Patients With Treatment-Resistant Depression • Efficacy of Opioid-free Anesthesia in Reducing Postoperative Respiratory Depression in Children Undergoing Tonsillectomy • Effect of Multimodal Opioid-free Anesthesia on Return of Bowel Function in Laparoscopic Colorectal Surgery • Techniques to Reduce the Severity and Frequency of Emergent Reactions • Study of Wafermine™ for Post-bunionectomy or Abdominoplasty Pain • Efficacy and Safety of TAK-653 in Treatment-Resistant Depression • Personality Disorders and Substance Use Disorders in a Sexual Context in the Man Having Sex With Other Men Population • Opioid Free Anesthesia in Bariatric Surgery • Opioid Free Anesthesia and Major Spine Surgery • UNderstanding CONSciousness Connectedness and Intraoperative Unresponsiveness Study • Modifying Virtual Reality Analgesia With Low-Dose Pain Medication • Opioid Free Anaesthesia in Cardiac Surgery With Cardiopulmonary Bypass • Quality of Recovery Following Opioids Free Anaesthesia in Laparoscopic Sleeve Gastrectomy • Efficacy of Opioid-free Anesthesia in Reducing Postoperative Pain in Chronic Pain Patients Undergoing Spinal Surgery • Smooth Extubation With Ketofol for Induction of General Anesthesia in Laparoscopic Drilling of Polycystic Ovary • Pharmacokinetics of Antiepileptics in Patients on CRRT • Developing Anesthesia as Post Traumatic Stress Disorder (PTSD) Therapy • Perioperative Analgesia on Postoperative Opioid Usage and Pain Control in H&N Cancer Surgery • Comparative Study of Nonintubated Anesthesia Versus Intubated General Anesthesia in Single Port Thoracoscopic Bullectomy • Prevention of Phantom Limb Pain After Transtibial Amputation • Impact of Pregabalin in Chronic Users vs. a Perioperative Limited Prescription on Oxycodone Requirement • Competition With Striatal [11C]ORM-13070 Binding by Atipamezole and Endogenous Noradrenaline • Laparoscopic Cholecystectomy: General Anesthesia With Opioid Versus General Opioid Free Anesthesia • Spinal Versus General Anesthesia With Popliteal and Adductor Canal Blocks for Ambulatory Foot and Ankle Surgery. • Influence of Anesthetic Technique on Acute and Chronic Neuropathic Pain • Heart Rate Variability in Depression • MRI Studies of Emotion in Depression • Multimodal Analgesia Versus Traditional Opiate Based Analgesia • Comparison of Three Different Strategies to Prevent Propofol Induced Pain During Infusion • Stepwise Shock Wave Lithotripsy in Pediatric Urolithiasis • US-guided SAPB for Rib Fractures in the ED • Effect of Intraoperative Anesthetic Management on Postoperative Nausea and Vomiting in Bariatric Surgery • Procedural Sedation And Analgesia in Children in the Emergency Department: The Role of Adjunct Therapies • Bier's Block Versus Systemic Analgesia • Paravertebral Nerve Blocks in Neonates • Hematoma Block as an Adjunct to Procedural Sedation for Forearm Fracture Reduction • Intranasal Esketamine and Fentanyl for Pain in Minor Trauma • Clinical Study to Assess Efficacy and Safety of Amiodarone in Treating Patients With Ebola. Virus Disease (EVD) in Sierra Leone. EASE (EMERGENCY Amiodarone Study Against Ebola) • A Prospective, Multi-center, Randomized Controlled Study of Muscle Relaxation Effect and Safety of Mivacurium Chloride in Pediatric Surgery Patients • GA vs. CS for Endovascular Stroke Therapy • Optimal Multimodal Analgesia in Abdominal Hysterectomy • The PATHFINDER Study: A Feasibility Trial • Multimodal Narcotic Limited Perioperative Pain Control With Colorectal Surgery • Optimal Multimodal Analgesia in Laparoscopic Cholecystectomy • GABA-glutamate Interactions and Psychosis • Pharmacokinetics and Pharmacodynamics of Nasally Applied Esketamine • Efficacy of Magnetic Resonance-guided High Intensity Focused Ultrasound for the Ablation of Breast Cancer • Transverse Abdominis Plane Block for Anterior Approach Spine Surgery • Effect of Opioid Free Anesthetic on Post-Operative Opioid Consumption After Laparoscopic Bariatric Surgery • Effect of Sevoflurane in Postoperative Troponin I Levels in Children Undergoing Congenital Heart Defects Surgery • Analgesic Efficacy of US-Guided Interscalene Block Versus Supraclavicular Block for Ambulatory Arthroscopic Rotator Cuff Repair • Opioid Free Anesthesia: What About Patient Comfort? • Preventing pAIn With NMDA Antagonists - Steroids in Thoracoscopic lObectomy Procedures (PAIN-STOP) Pilot Trial • GOAL-Directed ANalgesia (GOALDAN) • Prospective Analgesic Compound Efficacy (PACE) Study • Transversus Abdominis Plane Block Versus Quadratus Lumborum Block in The Pediatric Population Undergoing Orchiopexy • Opioid-free Total Hip Arthroplasty • Opioid Free vs Opioid Based Anesthesia for Laparoscopic Sleeve Gastrectomy • Evaluation of Spine Surgery Analgesic Pathway • IPACK Nerve Block for Total Knee Arthroplasty • GA/Spinal vs. GA/Spinal/NMB for Operative Repair of Hip Fracture • Evaluation of Anterior Quadratus Lumborum Block for Postoperative Analgesia in Hip Arthroscopy • Feasibility of Electro Auricular Acupuncture for Analgesia After ACL Surgery: The Feasibility of Patient Blinding and Effects on Early Postoperative Pain • Novel Topical Therapies for the Treatment of Genital Pain • Improving Pain and Reducing Opioid Use (IPaRO) in Lumbar Spine Surgery Patients • Neuropathic Evaluation of Postoperative Pain • Opioid Free Anesthesia and Bariatric Surgery • RelieVRx for Total Knee Arthroplasty (TKA) for the Reduction of Acute Postoperative Pain and Opioid Use • The Comparison of Different Administration Routes of Pediatric Premedication • Intravenous Sedation Versus General Anesthesia in Patients Undergoing Minor Gynecologic Surgery • Opiod Free Anaesthesia in Thoracic Surgery • Multimodal Analgesia vs. Routine Care Pain Management for Lumbar Spine Fusion Surgery: A Prospective Randomized Study • Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Performed Under General Anesthesia Versus Moderate Sedation • Impact of OFA During LPV on Postoperative Oxygen Saturation • The Effect of Etomidate on Patient Outcomes After Single Bolus Doses • MAC vs TIVA Ambulatory Breast Augmentation • Impact of Opioid Free Anesthesia on Outcome After Hip Arthroplasty by Direct Anterior Approach. • OS Impact of Opioid Free Anesthesia on Outcome After DIEPflap Surgery • Role of Low Dose Epinephrine Boluses In Acute Hypotension • IPACK Study in Total Knee Arthroplasty Patients • Efficacy Study Comparing Compounded Topical Pain Creams vs. Placebo for Treating Pain Symptoms • Preventative Delirium Protocol in Elderly Patients • Delirium Prevention Protocol in Elderly Patients • Effect of Position and Anesthetic Choice in Intraocular Pressure in Robotic GYN (Gynecologic) Oncology Patients • Opiod Free Anesthesia vs. Opioid Anesthesia Techniques. • Comparison of Two Sedation Versus Placebo Techniques During Cataract Surgery Under Local Anesthesia • Our Anesthesia Experience During MRI Scan • Real-time Decision Support for Postoperative Nausea and Vomiting (PONV) Prophylaxis • PEF-Block & Ribs Fractures • Effects of an Opioid Sparing Care Pathway for Patients Undergoing Obesity Surgery • EEG Monitoring in the Emergency Department • Impact of Pre-Sedation Virtual Reality Game on Post-Discharge Negative Behaviors in the Pediatric Emergency Department • A Multiple Ascending Dose Study of BCI-838 in Healthy Volunteers • A Study of BCI-838 and Several BCI-632 Prodrugs in Healthy Volunteers • Memantine Augmentation of Antidepressants • Measuring Analgesic Interventions • Enhanced Recovery After Surgery (ERAS) in Coronary Artery Bypass Graft / Off Pump Coronary Artery Bypass (CABG/OPCAB) • The Safety and Efficacy of the Enhanced Recovery After Surgery(ERAS)Applied on Cardiac Surgery With Cardiopulmonary Bypass • Evaluation of Ketamine as Sedative Agent in Endoscopic Retrograde Cholangiopancreatography (ERCP) • Ketamine for Older Adults Pilot • Intraperitoneal Dexmedetomidine Versus Ketamine With Bupivacaine For Postoperative Analgesia • Intraoperative Lidocaine and Combined With Ketamine on Opioid After Bariatric Surgery • Phase 1 Bioavailability Study of MELT-100 (Midazolam and Ketamine Sublingual) and IV Midazolam or Ketamine • Ketamine Versus Dexmedetomidine in Supraclavicular Brachial Plexus Block • Neuroprotection During Open Heart Surgery • University of Iowa Interventional Psychiatry Service Patient Registry • Vital Capacity in Ultrasound Guided Serratus Plane Block in ED Patients With Multiple Rib Fractures • Sevoflurane Insufflation vs Intravenous Sedation for Radiotherapy in Pediatric Patients • Duration of Anaesthesia Induction in Paediatric Patients: Prospective Observational Trial • A Practical, Pilot, Randomized, Controlled Trial of Valproate Alone or in Combination With Quetiapine for Severe COVID-19 Pneumonia With Agitated Delirium • Imaging Neural Correlates of Ketamine Using PET/MR • Reducing Adolescent Suicide Risk: Safety, Efficacy, and Connectome Phenotypes of Intravenous Ketamine • Ketamine in Patients Undergoing TEVAR Procedures Receiving NCI • Ketamine Versus Midazolam for Recurrence of Suicidality in Adolescents • Ketamine for Analgesia After Cesarean Section • Ketamine-enhanced Prolonged Exposure Therapy in PTSD • Glutamatergic Mechanisms of Psychosis and Target Engagement (SA1) • Ketamine Infusion vs Dexmedetomidine Infusion in Obese Patients Undergoing Bariatric Surgery • Ketamine or Neostigmine for Serratus Anterior Plane Block in Modified Radical Mastectomy • Dexmedetomidine Versus Ketamine Versus Midazolam in Endoscopic Procedures • Ketamine + Cognitive Training for Suicidality in the Medical Setting • Inpatient Single Dose Interventions for Alcohol Use Disorder • A Study in Healthy Men to Test Whether BI 409306, BI 425809 or Lamotrigine Can Reverse the Memory Problems Caused by Ketamine • Implications of Different Analgesic Models on Inflammatory Markers After Laparoscopic Cholecystectomy • Recommendations of Enhanced Recovery Interventions for Patient's Clinical Team and Collection of Associated Data • Cardiovascular Protection Conservative Effects of Esketamine Versus µ-opioid Receptor Agonists in General Anesthesia • Neurophysiological Monitoring and Videolaryngoscopy • A Multicenter Study of the Efficacy and Safety of Esketamine for Analgesia During Cesarean Section


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  • Response of cluster headache to psilocybin and LSD • Cross tolerance between LSD and psilocybin • Multiple serotonin receptors: differential binding of 5-hydroxytryptamine, lysergic acid diethylamide and spiroperidol • Serotonin and lysergic acid diethylamide binding in rat brain membranes: relationship to postsynaptic serotonin receptors • Lysergic acid diethylamide: side effects and complications • Lysergic acid diethylamide: sensitive neuronal units in the midbrain raphe • Evidence for a central 5-hydroxytryptamine receptor stimulation by lysergic acid diethylamide • The pharmacology of lysergic acid diethylamide: a review • Lysergic acid diethylamide (LSD) for alcoholism: meta-analysis of randomized controlled trials • The therapeutic value of lysergic acid diethylamide in mental illness • Lysergic acid diethylamide and serotonin: direct actions on serotonin-containing neurons in rat brain • Adverse consequences of lysergic acid diethylamide • Stereospecific binding ofd-lysergic acid diethylamide (LSD) to brain membranes: relationship to serotonin receptors • Chromosomal damage in human leukocytes induced by lysergic acid diethylamide • Amphetamine, 3, 4-methylenedioxymethamphetamine, lysergic acid diethylamide, and metabolites of the catecholamine neurotransmitters are agonists of a rat trace … • Safety and efficacy of lysergic acid diethylamide-assisted psychotherapy for anxiety associated with life-threatening diseases • The distribution and metabolism of lysergic acid diethylamide • Lysergic acid diethylamide and serotonin: a comparison of effects on serotonergic neurons and neurons receiving a serotonergic input • Acute effects of lysergic acid diethylamide in healthy subjects • Prolonged adverse reactions to lysergic acid diethylamide • Lysergic acid diethylamide (LSD-25): I. Physiological and perceptual responses • Effects of lysergic acid diethylamide on the metabolism of brain 5-hydroxytryptamine • The paradoxical psychological effects of lysergic acid diethylamide (LSD) • Persistence of lysergic acid diethylamide in the plasma of human subjects • Untoward reactions to lysergic acid diethylamide (LSD) resulting in hospitalization • Is lysergic-acid diethylamide a teratogen? • Use of d-Lysergic Acid Diethylamide in the Treatment of Alcoholism • Complications associated with lysergic acid diethylamide (LSD-25) • Study of lysergic acid diethylamide as an analgesic agent • Lysergic acid diethylamide (LSD-25) A clinical-psychological study • Antagonism of histamine-activated adenylate cyclase in brain by D-lysergic acid diethylamide • Mental changes experimentally produced by LSD (d-lysergic acid diethylamide tartrate.). • Experimental physiological studies with lysergic acid diethylamide (LSD-25) • Binding interactions of lysergic acid diethylamide and related agents with dopamine receptors in the brain • Neuropharmacological reassessment of the discriminative stimulus properties ofd-lysergic acid diethylamide (LSD) • Mescaline and lysergic acid diethylamide (LSD) as discriminative stimuli • 125I-lysergic acid diethylamide binds to a novel serotonergic site on rat choroid plexus epithelial cells • Congenital malformations induced by mescaline, lysergic acid diethylamide, and bromolysergic acid in the hamster • High-affinity binding of 5-hydroxytryptamine to brain synaptosomal membranes: comparison with lysergic acid diethylamide binding • Leukocytes of humans exposed to lysergic acid diethylamide: Lack of chromosomal damage • Further studies in the therapeutic value of lysergic acid diethylamide in mental illness • Variations in ego feeling induced by D-lysergic acid diethylamide (LSD-25) • Modern clinical research on LSD • LSD and genetic damage: Is LSD chromosome damaging, carcinogenic, mutagenic, or teratogenic? • LSD: A fast line segment detector with a false detection control • Neural correlates of the LSD experience revealed by multimodal neuroimaging • LSD: A line segment detector • Fisher's least significant difference (LSD) test • LSD-SLAM: Large-scale direct monocular SLAM
  • Direct Comparison of Altered States of Consciousness Induced by LSD and Psilocybin • LSD Treatment in Persons Suffering From Anxiety Symptoms in Severe Somatic Diseases or in Psychiatric Anxiety Disorders • Role of Dopamine, Serotonin and 5-HT2A Receptors in Emotion Processing • Mood Effects of Serotonin Agonists • Effects of MDMA Co-administration on the Response to LSD in Healthy Subjects • Lysergic Acid Diethylamide (LSD) as Treatment for Cluster Headache • Lysergic Acid Diethylamide (LSD)-Assisted Psychotherapy in People With Illness-related Anxiety • LSD Therapy for Persons Suffering From Major Depression • Effect of Ketanserin After LSD Administration • Neuronal Correlates of Altered States of Consciousness • Psychological, Physiological, Endocrine, and Pharmacokinetic Effects of LSD in a Controlled Study • The Role of 5-HT2A Receptor in the Perception of Self and Personal Meaning in Healthy Volunteers • A Double-blind, Placebo-controlled Study to Evaluate Very Low Dose LSD in Healthy Volunteers Aged 55-75 Years • Role of the Serotonin 5-HT2A Receptor in LSD-induced Altered States of Consciousness (LDR-Study) • Personality and Drug Use (PDU) • Effects of LSD on Neuroplasticity in Healthy Subjects • Effects of SERT Inhibition on the Subjective Response to LSD in Healthy Subjects • LSD Base and LSD Tartrate Bioequivalence and Bioavailability in Healthy Subjects


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  • Biochemical and histological evidence that methylenedioxymethylamphetamine (MDMA) is toxic to neurons in the rat brain. • Non‐linear pharmacokinetics of MDMA ('ecstasy') in humans • Positron emission tomographic evidence of toxic effect of MDMA (“Ecstasy”) on brain serotonin neurons in human beings • The pharmacology and clinical pharmacology of 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”) • The molecular mechanism of" ecstasy": serotonin transporters are targets for MDMA-induced serotonin release. • Psychological and cardiovascular effects and short-term sequelae of MDMA (“ecstasy”) in MDMA-naıve healthy volunteers • Ecstasy (MDMA) effects upon mood and cognition: before, during and after a Saturday night dance • … effects of the serotonergic neurotoxicant (+/-)-3, 4-methylenedioxymethamphetamine (MDMA) correlates with the magnitude of the MDMA-induced thermal response. • Effects of dose, sex, and long-term abstention from use on toxic effects of MDMA (ecstasy) on brain serotonin neurons • 'Eve'and'ecstasy': A report of five deaths associated with the use of MDEA and MDMA • MDMA-induced neurotoxicity: parameters of degeneration and recovery of brain serotonin neurons • Subjective reports on the effects of the MDMA (" ecstasy") experience in humans. • Small changes in ambient temperature cause large changes in 3, 4-methylenedioxymethamphetamine (MDMA)-induced serotonin neurotoxicity and core body … • Neurochemistry and neurotoxicity of 3, 4‐methylenedioxymethamphetamine (MDMA,“ecstasy”) • Cognitive performance in (±) 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”) users: a controlled study • 3, 4‐Methylenedioxymethamphetamine (MDMA,“Ecstasy”): pharmacology and toxicology in animals and humans • Review of the pharmacology and clinical pharmacology of 3, 4-methylenedioxymethamphetamine (MDMA or “Ecstasy”) • Memory impairment in abstinent MDMA (" Ecstasy") users • Toxic effects of MDMA on central serotonergic neurons in the primate: importance of route and frequency of drug administration • Gender differences in the subjective effects of MDMA • 3, 4-Dihydroxymethamphetamine (HHMA). A major in vivo 3, 4-methylenedioxymethamphetamine (MDMA) metabolite in humans • Methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) cause selective ablation of serotonergic axon terminals in forebrain … • Serotonin neurotoxicity after (±) 3, 4-methylenedioxymethamphetamine (MDMA;“Ecstasy”): a controlled study in humans • Reorganization of ascending 5-HT axon projections in animals previously exposed to the recreational drug (+/-) 3, 4-methylenedioxymethamphetamine (MDMA," … • Mood and cognitive effects of±3, 4‐methylenedioxymethamphetamine (MDMA,'ecstasy'): week‐end 'high'followed by mid‐week low • Differences between the mechanism of action of MDMA, MBDB, and the classic hallucinogens. Identification of a new therapeutic class: entactogens • Pharmacologic profile of MDMA (3, 4-methylenedioxymethamphetamine) at various brain recognition sites • Cortical serotonin transporter density and verbal memory in individuals who stopped using 3, 4-methylenedioxymethamphetamine (MDMA or ecstasy): preliminary … • 3, 4-Methylenedioxymethamphetamine (MDMA) neurotoxicity in rats: a reappraisal of past and present findings • Human pharmacology of MDMA: pharmacokinetics, metabolism, and disposition • The effects of 3, 4-methylenedioxymethamphetamine (MDMA) and 3, 4-methylenedioxyamphetamine (MDA) on monoaminergic systems in the rat brain • Acute psychological effects of 3, 4-methylenedioxymethamphetamine (MDMA,“Ecstasy”) are attenuated by the serotonin uptake inhibitor citalopram • Cognitive performance in recreational users of MDMA or'ecstasy': Evidence for memory deficits • Which neuroreceptors mediate the subjective effects of MDMA in humans? A summary of mechanistic studies • Psychological and physiological effects of MDMA (“Ecstasy”) after pretreatment with the 5-HT 2 antagonist ketanserin in healthy humans • Self-administration of methylenedioxymethamphetamine (MDMA) by rhesus monkeys • The pharmacology of the acute hyperthermic response that follows administration of 3, 4‐methylenedioxymethamphetamine (MDMA,'ecstasy') to rats • The pharmacology and toxicology of “ecstasy”(MDMA) and related drugs • Determination of MDMA and its metabolites in blood and urine by gas chromatography-mass spectrometry and analysis of enantiomers by capillary electrophoresis • Memory deficits associated with recreational use of “ecstasy”(MDMA) • Subjective and hormonal effects of 3, 4-methylenedioxymethamphetamine (MDMA) in humans • Human psychopharmacology of Ecstasy (MDMA): a review of 15 years of empirical research • The effects of methylenedioxymethamphetamine (MDMA,“Ecstasy”) on monoaminergic neurotransmission in the central nervous system • Is ecstasy MDMA? A review of the proportion of ecstasy tablets containing MDMA, their dosage levels, and the changing perceptions of purity • Reduced in vivo binding to the serotonin transporter in the cerebral cortex of MDMA ('ecstasy') users • Recreational MDMA use in Sydney: a profile of 'Ecstasy'users and their experiences with the drug • Effects of enantiomers of MDA, MDMA and related analogues on serotonin and dopamine release from superfused rat brain slices • A randomized, controlled pilot study of MDMA (±3, 4-Methylenedioxymethamphetamine)-assisted psychotherapy for treatment of resistant, chronic Post-Traumatic … • Severe dopaminergic neurotoxicity in primates after a common recreational dose regimen of MDMA (" ecstasy") • Aminergic Metabolites in Cerebrospinal Fluid of Humans Previously Exposed to MDMA: Preliminary Observationsa • Pharmacology of MDMA in humans • 3, 4-methylenedioxymethamphetamine (MDMA,“Ecstasy”) induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro • Quantitative PET studies of the serotonin transporter in MDMA users and controls using McN5652 and DASB • Subjective reports of the effects of MDMA in a clinical setting • Stereochemical effects of 3, 4-methylenedioxymethamphetamine (MDMA) and related amphetamine derivatives on inhibition of uptake of monoamines into … • The origin of MDMA (ecstasy) revisited: the true story reconstructed from the original documents • MDMA (ecstasy') consumption in the context of polydrug abuse: a report on 150 patients • MDMA (ecstasy) inhibition of MAO type A and type B: comparisons with fenfluramine and fluoxetine (Prozac) • Ketanserin pretreatment attenuates MDMA-induced dopamine release in the striatum as measured by in vivo microdialysis • Neurotoxicity of MDMA and Related Compounds: Anatomic Studiesa • Toxicodynamics and long-term toxicity of the recreational drug, 3, 4-methylenedioxymethamphetamine (MDMA,'Ecstasy') • Recreational use of “ecstasy”(MDMA) is associated with elevated impulsivity • The hyperthermic and neurotoxic effects of 'Ecstasy'(MDMA) and 3, 4 methylenedioxyamphetamine (MDA) in the Dark Agouti (DA) rat, a model of the CYP2D6 poor … • MDMA enhances emotional empathy and prosocial behavior • Ecstasy (MDMA): a review of its possible persistent psychological effects • Psychobiological problems in heavy 'ecstasy'(MDMA) polydrug users • Neurotoxicity of MDMA (ecstasy): the limitations of scaling from animals to humans • MDMA (ecstasy) and the rave: a review • Acute toxic effects of 'Ecstasy'(MDMA) and related compounds: overview of pathophysiology and clinical management • 3, 4-Methylenedioxymethamphetamine (MDMA," ecstasy") and its stereoisomers as reinforcers in rhesus monkeys: serotonergic involvement • Mephedrone, compared with MDMA (ecstasy) and amphetamine, rapidly increases both dopamine and 5‐HT levels in nucleus accumbens of awake rats • MDMA induced dopamine release in vivo: role of endogenous serotonin • Drug discrimination studies with MDMA and amphetamine • N-substituted piperazines abused by humans mimic the molecular mechanism of 3, 4-methylenedioxymethamphetamine (MDMA, or 'Ecstasy') • Impaired cognitive performance in drug free users of recreational ecstasy (MDMA) • Co-administration of MDMA with drugs that protect against MDMA neurotoxicity produces different effects on body temperature in the rat • Ecstasy, 3–4 methylenedioxymethamphetamine (MDMA), a fatality associated with coagulopathy and hyperthermia • MDMA (Ecstasy) and human dopamine, norepinephrine, and serotonin transporters: implications for MDMA-induced neurotoxicity and treatment • Working memory deficits in current and previous users of MDMA ('ecstasy') • The relationship between the degree of neurodegeneration of rat brain 5-HT nerve terminals and the dose and frequency of administration of MDMA (ecstasy') • Chronic 3, 4-methylenedioxymethamphetamine (MDMA) use: effects on mood and neuropsychological function? • Multiple severe complications from recreational ingestion of MDMA ('ecstasy') • Simultaneous liquid chromatographic-electrospray ionization mass spectrometric quantification of 3, 4-methylenedioxymethamphetamine (MDMA, Ecstasy) and its … • Incidence of recreational use of 3, 4-methylenedimethoxymethamphetamine (MDMA," ecstasy") on an undergraduate campus. • Differences in the central serotonergic effects of methylenedioxymethamphetamine (MDMA) in mice and rats • Behavioral and neurochemical effects of orally administered MDMA in the rodent and nonhuman primate. • Low-dose MDMA (“ecstasy”) induces vasopressin secretion • Localization of MDMA‐induced brain activity in healthy volunteers using low resolution brain electromagnetic tomography (LORETA) • Serotonergic-dopaminergic mediation of 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”) • Recreational Ecstasy/MDMA, the serotonin syndrome, and serotonergic neurotoxicity • 3,4-Methylenedioxymethamphetamine (MDMA): Stereoselective interactions at brain 5-HT1 and 5-HT2 receptors • 3, 4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for post-traumatic stress disorder in military veterans, firefighters, and police officers: a … • Is MDMA ('Ecstasy') neurotoxic in humans? An overview of evidence and of methodological problems in research • Cocaine, MDMA and methamphetamine residues in wastewater: Consumption trends (2009–2015) in South East Queensland, Australia • MDMA elicits behavioral and neurochemical sensitization in rats • Effect of ecstasy on cerebral blood flow: a co-registered SPECT and MRI study • The background and chemistry of MDMA • MDMA ('ecstasy') use, and its association with high risk behaviors, mental health, and other factors among gay/bisexual men in New York City • Acute psychological and physiological effects of MDMA (“Ecstasy”) after haloperidol pretreatment in healthy humans • MDMA (“Ecstasy”) abuse and high-risk sexual behaviors among 169 gay and bisexual men • Self-injection of d,1-3,4-methylenedioxymethamphetamine (MDMA) in the baboon • Chronic MDMA (ecstasy) use, cognition and mood • The psychological and physiological effects of MDMA on normal volunteers • Ecstasy (MDMA) in recreational users: self‐reported psychological and physiological effects • Development, maintenance and temporal pattern of self-administration maintained by ecstasy (MDMA) in rats • A study of the neurotoxic effect of MDMA ('ecstasy') on 5‐HT neurones in the brains of mothers and neonates following administration of the drug during pregnancy • Ascorbic acid prevents 3, 4‐methylenedioxymethamphetamine (MDMA)‐induced hydroxyl radical formation and the behavioral and neurochemical consequences of … • Acute and subchronic effects of methylenedioxymethamphetamine on locomotion and serotonin syndrome behavior in the rat • Differences between rats and mice in MDMA (methylenedioxymethylamphetamine) neurotoxicity • In vivo evidence for free radical involvement in the degeneration of rat brain 5‐HT following administration of MDMA ('ecstasy') and p‐chloroamphetamine but not the … • Residual neuropsychological effects of illicit 3, 4-methylenedioxymethamphetamine (MDMA) in individuals with minimal exposure to other drugs • 3, 4-Methylenedioxymethamphetamine (MDMA) as a unique model of serotonin receptor function and serotonin-dopamine interactions • The confounding problem of polydrug use in recreational ecstasy/MDMA users: a brief overview • Preliminary evidence of hippocampal dysfunction in adolescent MDMA (“ecstasy”) users: possible relationship to neurotoxic effects • MDMA induced hyperthermia: report of a fatality and review of current therapy • Methylenedioxymethamphetamine (MDMA, Ecstasy) neurotoxicity: cellular and molecular mechanisms • Analysis of 3, 4-methylenedioxymethamphetamine (MDMA) and its metabolites in plasma and urine by HPLC-DAD and GC-MS • Lasting effects of (+-)-3, 4-methylenedioxymethamphetamine (MDMA) on central serotonergic neurons in nonhuman primates: neurochemical observations. • Pursuit of ecstasy: The MDMA experience • A review of the mechanisms involved in the acute MDMA (ecstasy)-induced hyperthermic response • Reinforcing, subjective, and physiological effects of MDMA in humans: a comparison with d-amphetamine and mCPP • Thermoregulatory effects of 3, 4-methylenedioxymethamphetamine (MDMA) in humans • Chronic tolerance to recreational MDMA (3, 4-methylenedioxymethamphetamine) or Ecstasy • Persistent effects of (±) 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”) on human sleep • Effects of MDMA on sociability and neural response to social threat and social reward • Neurotoxicity of MDMA: neurochemical effects • The pre-clinical behavioural pharmacology of 3, 4-methylenedioxymethamphetamine (MDMA) • A bitter pill. Overview of ecstasy (MDMA, MDA) related fatalities • Ecstasy (MDMA) dependence • Adverse reactions with 3, 4-methylenedioxymethamphetamine (MDMA;'ecstasy') • Memory impairment in abstinent MDMA (“ecstasy”) users: a longitudinal investigation • Effects of the selective 5-HT 2A receptor antagonist MDL 100,907 on MDMA-induced locomotor stimulation in rats • Reduced cortical gray matter density in human MDMA (Ecstasy) users: a voxel-based morphometry study • Increasing MDMA use among college students: results of a national survey • MDMA (“Ecstasy”) and its association with cerebrovascular accidents: preliminary findings • MDMA in humans: factors which affect the neuropsychobiological profiles of recreational ecstasy users, the integrative role of bioenergetic stress • 3, 4-Methylenedioxymethamphetamine (MDMA) modulates cortical and limbic brain activity as measured by -PET in healthy humans • Mood, cognition and serotonin transporter availability in current and former ecstasy (MDMA) users: the longitudinal perspective • Causes and consequences of methamphetamine and MDMA toxicity • MDMA (3, 4-Methylenedioxymethamphetamine) or ecstasy: the neuropsychobiological implications of taking it at dances and raves • Elevated impulsivity and impaired decision-making cognition in heavy users of MDMA (“Ecstasy”) • Actions of 3, 4-methylenedioxymethamphetamine (MDMA) on cerebral dopaminergic, serotonergic and cholinergic neurons • MDMA enhances “mind reading” of positive emotions and impairs “mind reading” of negative emotions • Differential effects of MDMA, cocaine, and cannabis use severity on distinctive components of the executive functions in polysubstance users: a multiple regression … • MDMA: a review of epidemiological data • Repeated doses administration of MDMA in humans: pharmacological effects and pharmacokinetics • Effects of MDMA (ecstasy) on prepulse inhibition and habituation of startle in humans after pretreatment with citalopram, haloperidol, or ketanserin • The acute and chronic effects of MDMA (“ecstasy”) on cortical 5-HT 2A receptors in rat and human brain • The subjective effects of MDMA and mCPP in moderate MDMA users • Sub-acute effects of MDMA (±3, 4-methylenedioxymethamphetamine," ecstasy") on mood: evidence of gender differences • Ecstasy (MDMA): are the psychological problems associated with its use reversed by prolonged abstinence? • Acute, sub‐acute and long‐term subjective consequences of 'ecstasy'(MDMA) consumption in 430 regular users • “Partying” hard: party style, motives for and effects of MDMA use at rave parties • Electrophysiological evidence of serotonergic impairment in long-term MDMA (“ecstasy”) users • Acute and long-term effects of MDMA on cerebral dopamine biochemistry and function • A neurotoxic regimen of MDMA suppresses behavioral, thermal and neurochemical responses to subsequent MDMA administration • Respondent-driven sampling to recruit MDMA users: a methodological assessment • Chronic paranoid psychosis after misuse of MDMA (" ecstasy") • 5‐HT loss in rat brain following 3, 4‐methylenedioxymethamphetamine (MDMA), p‐chloroamphetamine and fenfluramine administration and effects of … • Increased intensity of Ecstasy and polydrug usage in the more experienced recreational Ecstasy/MDMA users: a WWW study • MDMA-assisted psychotherapy for treatment of PTSD: study design and rationale for phase 3 trials based on pooled analysis of six phase 2 randomized … • A study of the mechanisms involved in the neurotoxic action of 3, 4‐methylenedioxymethamphetamine (MDMA,'ecstasy') on dopamine neurones in mouse brain • Effect of GBR 12909 and fluoxetine on the acute and long term changes induced by MDMA ('ecstasy') on the 5-HT and dopamine concentrations in mouse brain • Neurotoxicity of methylenedioxyamphetamines (MDMA; ecstasy) in humans: how strong is the evidence for persistent brain damage? • Subjective effects of MDMA ('Ecstasy') on human sexual function • Neuroendocrine and mood responses to intravenous L-tryptophan in 3, 4-methylenedioxymethamphetamine (MDMA) users: preliminary observations • Hyperpyrexia and rhaddomyolysis after MDMA (ecstasy) abuse • Neurochemical and neurohistological alterations in the rat and monkey produced by orally administered methylenedioxymethamphetamine (MDMA) • Recreational ecstasy/MDMA and other drug users from the UK and Italy: psychiatric symptoms and psychobiological problems • Ecstasy/MDMA attributed problems reported by novice, moderate and heavy recreational users • Striatal serotonin is depleted in brain of a human MDMA (Ecstasy) user • In vivo detection of short‐and long‐term MDMA neurotoxicity—a positron emission tomography study in the living baboon brain • Increased anxiety 3 months after brief exposure to MDMA ('Ecstasy') in rats: association with altered 5-HT transporter and receptor density • Effect of ambient temperature on hyperthermia and hyperkinesis induced by 3, 4-methylenedioxymethamphetamine (MDMA or “ecstasy”) in rats • A review of the acute subjective effects of MDMA/ecstasy • Human research on MDMA (3, 4-methylene-dioxymethamphetamine) neurotoxicity: cognitive and behavioural indices of change • Mood, cognition and serotonin transporter availability in current and former ecstasy (MDMA) users • Level of use of 3, 4-methylenedioxymethamphetamine (MDMA or Ecstasy) in humans correlates with EEG power and coherence • MDMA ('ecstasy') and other'club drugs'. The new epidemic. • Hyperthermia following MDMA administration in rats: effects of ambient temperature, water consumption, and chronic dosing • α-Lipoic acid prevents 3, 4-methylenedioxy-methamphetamine (MDMA)-induced neurotoxicity • Effects of MDMA (ecstasy), and multiple drugs use on (simulated) driving performance and traffic safety • Pharmacokinetic and pharmacodynamic effects of methylphenidate and MDMA administered alone or in combination • How could MDMA (ecstasy) help anxiety disorders? A neurobiological rationale • Memory deficits in abstinent MDMA (ecstasy) users: neuropsychological evidence of frontal dysfunction • Acute effects of 3, 4-methylenedioxymethamphetamine (MDMA) on behavioral measures of impulsivity: alone and in combination with alcohol • MDMA (“Ecstasy”) and panic disorder: induction by a single dose • Acute effects of 3, 4-methylenedioxymethamphetamine (MDMA) on monoamines in rat caudate • Role of hyperthermia in the protective action of clomethiazole against MDMA ('ecstasy')‐induced neurodegeneration, comparison with the novel NMDA channel … • MDMA (“ecstasy”), methamphetamine and their combination: long-term changes in social interaction and neurochemistry in the rat • A method of conducting therapeutic sessions with MDMA • Long-term neuropsychiatric consequences of" ecstasy"(MDMA): a review • Opposite effects of 3, 4-methylenedioxymethamphetamine (MDMA) on sensorimotor gating in rats versus healthy humans • Duloxetine Inhibits Effects of MDMA (“Ecstasy") In Vitro and in Humans in a Randomized Placebo-Controlled Laboratory Study • Club drugs: MDMA, gamma-hydroxybutyrate (GHB), Rohypnol, and ketamine • Fatal interaction between ritonavir and MDMA • Construct validity of the balloon analogue risk task (BART): Relationship with MDMA use by inner-city drug users in residential treatment • Behavioral and neurochemical consequences of long-term intravenous self-administration of MDMA and its enantiomers by rhesus monkeys • Cerebral 1H MRS alterations in recreational 3,4‐methylenedioxymethamphetamine (MDMA, “ecstasy”) users • … in the degeneration of 5‐HT nerve endings in the brain of Dark Agouti rats following 3, 4‐methylenedioxymethamphetamine (MDMA or 'ecstasy') administration • The complications of'ecstasy'(MDMA) • Cognitive function and mood in MDMA/THC users, THC users and non-drug using controls • The abused drug MDMA (Ecstasy) induces programmed death of human serotonergic cells • Long-term changes in social interaction and reward following repeated MDMA administration to adolescent rats without accompanying serotonergic neurotoxicity • Neuropsychological evidence of a relatively selective profile of temporal dysfunction in drug-free MDMA (" ecstasy") polydrug users • Recreational use of 3, 4-methylenedioxymethamphetamine (MDMA) or'ecstasy': evidence for cognitive impairment • The mechanisms involved in the long‐lasting neuroprotective effect of fluoxetine against MDMA ('ecstasy')‐induced degeneration of 5‐HT nerve endings in rat brain • MDMA: Nonmedical use and intoxication • (±)-3, 4-Methylenedioxymethamphetamine (MDMA,'Ecstasy') increases social interaction in rats • Structure of continuously cooled low-carbon vanadium steels • MDMA polydrug users show processspecific central executive impairments coupled with impaired social and emotional judgement processes • Behavioural analysis of the acute and chronic effects of MDMA treatment in the rat • Reward-related decision-making deficits and elevated impulsivity among MDMA and other drug users • Locomotor response to MDMA is attenuated in knockout mice lacking the 5-HT1B receptor • Human psychobiology of MDMA or 'Ecstasy': an overview of 25 years of empirical research • MDMA use and neurocognition: a meta-analytic review • Fatalities caused by the MDMA-related drug paramethoxyamphetamine (PMA) • The norepinephrine transporter inhibitor reboxetine reduces stimulant effects of MDMA (“ecstasy”) in humans • MDMA (Ecstasy) neurotoxicity: assessing and communicating the risks • Contribution of cannabis and MDMA (" ecstasy") to cognitive changes in long-term polydrug users • Importance of ERK activation in behavioral and biochemical effects induced by MDMA in mice • The psychotherapeutic potential of MDMA (3, 4-methylenedioxymethamphetamine): an evidence-based review • MDMA-assisted psychotherapy using low doses in a small sample of women with chronic posttraumatic stress disorder • Fatal multi-organ failure after suicidal overdose with MDMA,Ecstasy': case report and review of the literature • Long term psychiatric and cognitive effects of MDMA use • Methylenedioxymethamphetamine (MDMA,'Ecstasy'): a stressor on the immune system • Development of a lidar system for measuring methane using a gas correlation method • Altered neuroendocrine and behavioral responses to m-chlorophenylpiperazine in 3, 4-methylenedioxymethamphetamine (MDMA) users • Distribution of 3, 4-methylenedioxymethamphetamine (MDMA) and 3, 4-methylenedioxyamphetamine (MDA) stereoisomers in a fatal poisoning • Methylphenidate and MDMA adolescent exposure in mice: long-lasting consequences on cocaine-induced reward and psychomotor stimulation in adulthood • Brain hyperthermia induced by MDMA ('ecstasy'): modulation by environmental conditions • Demonstration and localization of neuronal degeneration in the rat forebrain following a single exposure to MDMA • mechanisms and management of hepatotoxicity in ecstasy (MDMA) and amphetamine intoxications. • Neurotoxic effects of MDMA on brain serotonin neurons: evidence from neurochemical and radioligand binding studies. • The effects of fluoxetine on the subjective and physiological effects of 3, 4-methylenedioxymethamphetamine (MDMA) in humans • A comprehensive review of MDMA and GHB: two common club drugs • Lack of serotonin neurotoxicity after intraraphe microinjection of (+)-3, 4-methylenedioxymethamphetamine (MDMA) • A clinical plan for MDMA (Ecstasy) in the treatment of posttraumatic stress disorder (PTSD): partnering with the FDA • Differential contributions of dopamine D 1, D 2, and D 3 receptors to MDMA-induced effects on locomotor behavior patterns in mice • Increased anxiety and" depressive" symptoms months after MDMA (" ecstasy") in rats: drug-induced hyperthermia does not predict long-term outcomes • Neuroanatomic specificity and time course of alterations in rat brain serotonergic pathways induced by MDMA (3, 4‐methylenedioxymethamphetamine): assessment … • Assessment of the discriminative stimulus effects of the optical isomers of ecstasy (3, 4-methylenedioxymethamphetamine; MDMA). • Chlormethiazole, dizocilpine and haloperidol prevent the degeneration of serotonergic nerve terminals induced by administration of MDMA ('Ecstasy') to rats • Life-threatening interactions between HIV-1 protease inhibitors and the illicit drugs MDMA and γ-hydroxybutyrate • Hippocampal serotonergic damage induced by MDMA (ecstasy): effects on spatial learning • Hyponatraemic states following 3, 4‐methylenedioxymethamphetamine (MDMA,'ecstasy') ingestion • Impulsivity, risk taking and recreational 'ecstasy'(MDMA) use • MDMA and human sexual function • MDMA (Ecstasy) precipitation of panic disorder • Memory function and serotonin transporter promoter gene polymorphism in ecstasy (MDMA) users • Reinforcing effects of MDMA ('ecstasy') in drug-naive and cocaine-trained rats • Concurrent use of methamphetamine, MDMA, LSD, ketamine, GHB, and flunitrazepam among American youths • Influence of inducers and inhibitors on the metabolism in vitro and neurochemical effects in vivo of MDMA. • Ecstasy: The complete guide: A comprehensive look at the risks and benefits of MDMA • Death following ingestion of MDMA (ecstasy) and moclobemide • Memory deficit and reduced anxiety in young adult rats given repeated intermittent MDMA treatment during the periadolescent period • MDMA and sexual behavior: Ecstasy users' perceptions about sexuality and sexual risk • 3, 4‐methylenedioxymethamphetamine (MDMA) administration to rats decreases brain tissue serotonin but not serotonin transporter protein and glial fibrillary acidic … • Serotonin–GABA interactions modulate MDMA‐induced mesolimbic dopamine release • Potential human neurotoxicity of MDMA ('Ecstasy'): subjective self-reports, evidence from an Italian drug addiction centre and clinical case studies • Chronic fluoxetine treatment partly attenuates the long-term anxiety and depressive symptoms induced by MDMA ('Ecstasy') in rats • Cerebral oedema after ingestion of MDMA (“ecstasy”) and unrestricted intake of water • MDMA self‐administration in rats: acquisition, progressive ratio responding and serotonin transporter binding • MDMA-assisted psychotherapy for PTSD: are memory reconsolidation and fear extinction underlying mechanisms? • Implications of mechanism-based inhibition of CYP2D6 for the pharmacokinetics and toxicity of MDMA • Rapid analysis of amphetamine, methamphetamine, MDA, and MDMA in urine using solid-phase microextraction, direct on-fiber derivatization, and analysis by GC … • Differential effects of MDMA and methylphenidate on social cognition • The effects of MDMA and other methylenedioxy-substituted phenylalkylamines on the structure of rat locomotor activity. • MDMA ('ecstasy') enhances basal acetylcholine release in brain slices of the rat striatum • A role for the mesolimbic dopamine system in the psychostimulant actions of MDMA • Ecstacy: a review of MDMA and MDA • Multiple 5-HT receptors are involved in the effects of acute MDMA treatment: studies on locomotor activity and responding for conditioned reinforcement • Estimating the relative reinforcing strength of (±)-3, 4-methylenedioxymethamphetamine (MDMA) and its isomers in rhesus monkeys: comparison to (+) … • Chronic atypical psychosis associated with MDMA (ecstasy) abuse • MDMA: the dark side of Ecstasy • Locomotor stimulation produced by 3, 4-methylenedioxymethamphetamine (MDMA) is correlated with dialysate levels of serotonin and dopamine in rat brain • Causes and consequences of the loss of serotonergic presynapses elicited by the consumption of 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”) and its … • MDMA and alcohol effects, combined and alone, on objective and subjective measures of actual driving performance and psychomotor function • The spatial epidemiology of cocaine, methamphetamine and 3, 4‐methylenedioxymethamphetamine (MDMA) use: a demonstration using a population measure of … • Neuroimaging research in human MDMA users: a review • Effects of MDMA and intranasal oxytocin on social and emotional processing • Acute psychological and neurophysiological effects of MDMA in humans • Superoxide radicals mediate the biochemical effects of methylenedioxymethamphetamine (MDMA): evidence from using CuZn‐superoxide dismutase transgenic mice • Prepulse inhibition and habituation of acoustic startle response in male MDMA ('ecstasy') users, cannabis users, and healthy controls • Effect of 3, 4-methylenedioxymethamphetamine (MDMA) on hippocampal dopamine and serotonin • Persistent MDMA‐induced dopaminergic neurotoxicity in the striatum and substantia nigra of mice • MDMA (Ecstasy') enhances 5-HT1A receptor density and 8-OH-DPAT-induced hypothermia: blockade by drugs preventing 5-hydroxytryptamine depletion • Caffeine promotes hyperthermia and serotonergic loss following co-administration of the substituted amphetamines, MDMA (“Ecstasy”) and MDA (“Love”) • Symptoms of anxiety and depression in childhood and use of MDMA: prospective, population based study • Profiles of urine samples from participants at rave party in Taiwan: prevalence of ketamine and MDMA abuse • Reduction in social anxiety after MDMA-assisted psychotherapy with autistic adults: a randomized, double-blind, placebo-controlled pilot study • Impaired executive function in male MDMA (“ecstasy”) users • Agony and ecstasy: a review of MDMA effects and toxicity • Elevation of ambient room temperature has differential effects on MDMA-induced 5-HT and dopamine release in striatum and nucleus accumbens of rats • MDMA (3, 4-methylenedioxymethamphetamine) inhibits the firing of dorsal raphe neurons in brain slices via release of serotonin • Quantitative and qualitative analysis of MDMA, MDEA, MA and amphetamine in urine by head-space/solid phase micro-extraction (SPME) and GC/MS • MDMA (ecstasy) effects on cultured serotonergic neurons: evidence for Ca2+-dependent toxicity linked to release • The threshold lowering effects of MDMA (ecstasy) on brain-stimulation reward • Former chronic methylenedioxymethamphetamine (MDMA or ecstasy) users report mild depressive symptoms • … dismutase (CuZnSOD) transgenic mice show resistance to the lethal effects of methylenedioxyamphetamine (MDA) and of methylenedioxymethamphetamine (MDMA … • Increasing use of “ecstasy “(MDMA) and other hallucinogens on a college campus • Stimulant effects of 3, 4‐methylenedioxymethamphetamine (MDMA) 75 mg and methylphenidate 20 mg on actual driving during intoxication and withdrawal • Dance clubbing on MDMA and during abstinence from Ecstasy/MDMA: prospective neuroendocrine and psychobiological changes • Toxic effect of MDMA on brain serotonin neurons • Cell‐mediated immune response in MDMA users after repeated dose administration: studies in controlled versus noncontrolled settings • Pharmacokinetic profile of single and repeated oral doses of MDMA in squirrel monkeys: relationship to lasting effects on brain serotonin neurons • Oxytocin-dependent reopening of a social reward learning critical period with MDMA • The role of monoamines in the changes in body temperature induced by 3, 4‐methylenedioxymethamphetamine (MDMA, ecstasy) and its derivatives • A neurotoxic dose of 3, 4-methylenedioxymethamphetamine (MDMA; ecstasy) to rats results in a long term defect in thermoregulation • MDMA (“ecstasy”) abuse: psychopathological features and craving for chocolate: a case series • Neurotoxicity of drugs of abuse-the case of methylenedioxy amphetamines (MDMA, ecstasy), and amphetamines • Role of the endocannabinoid system in MDMA intracerebral self‐administration in rats • 3, 4-Methylenedioxymethamphetamine (MDMA) abuse may cause oxidative stress and potential free radical damage • Increased sensitivity to the acute effects of MDMA (“ecstasy”) in female rats • … amphetamine, methamphetamine, methylenedioxyamphetamine (MDA), methylenedioxymethamphetamine (MDMA), and methylenedioxyethylamphetamine (MDEA) … • … neurotoxic dose of 3, 4-methylenedioxymethamphetamine (MDMA) on the hyperthermic response of rats to a single or repeated ('binge'ingestion) low dose of MDMA • Subarachnoid haemorrhage associated with MDMA abuse. • Effects of the serotonin releasers 3, 4-methylenedioxymethamphetamine (MDMA), 4-chloroamphetamine (PCA) and fenfluramine on acoustic and tactile startle … • Reserpine attenuates D-amphetamine and MDMA-induced transmitter release in vivo: a consideration of dose, core temperature and dopamine synthesis • The effect of 3, 4‐methylenedioxymethamphetamine (MDMA,? ecstasy?) and its metabolites on neurohypophysial hormone release from the isolated rat … • Detection of “bath salts” and other novel psychoactive substances in hair samples of ecstasy/MDMA/“Molly” users • A direct comparison of the behavioral and physiological effects of methamphetamine and 3, 4-methylenedioxymethamphetamine (MDMA) in humans • Role of metabolites in MDMA (ecstasy)-induced nephrotoxicity: an in vitro study using rat and human renal proximal tubular cells • Effect of the R (−) and S (+) isomers of MDA and MDMA on phosphotidyl inositol turnover in cultured cells expressing 5-HT2A or 5-HT2C receptors • Immunomodulating properties of MDMA alone and in combination with alcohol: a pilot study • Effect of MDMA (ecstasy) on activity and cocaine conditioned place preference in adult and adolescent rats • Physiological and subjective responses to controlled oral MDMA administration • A study of the effect of a single neurotoxic dose of 3, 4-methylenedioxymethamphetamine (MDMA;" ecstasy") on the subsequent long-term behaviour of rats in the plus … • The agony of ecstasy: MDMA (3, 4-methylenedioxymethamphetamine) and the kidney • Orally administered MDMA causes a long-term depletion of serotonin in rat brain • Psychosocial profiles of older adolescent MDMA users • Safety pharmacology of acute MDMA administration in healthy subjects • Cannabis and Ecstasy/MDMA (3, 4-methylenedioxymethamphetamine): an analysis of their neuropsychobiological interactions in recreational users • Effects of repeated doses of MDMA (“ecstasy”) on cell-mediated immune response in humans • Effects of MDMA exposure on the conditioned place preference produced by other drugs of abuse • Toxicity of MDA (3, 4-methylenedioxyamphetamine) considered for relevance to hazards of MDMA (Ecstasy) abuse. • Cannabinoids prevent the acute hyperthermia and partially protect against the 5-HT depleting effects of MDMA (“Ecstasy”) in rats • Persistent loss of thermoregulation in the rat induced by 3, 4-methylenedioxymethamphetamine (MDMA or “Ecstasy”) but not by fenfluramine • MDMA ('Ecstasy') and methamphetamine combined: order of administration influences hyperthermic and long-term adverse effects in female rats • Involvement of free radicals in MDMA-induced neurotoxicity in mice. • MDMA produces a conditioned place preference and elicits ejaculation in male rats: a modulatory role for the endogenous opioids • A comparative study on the acute and long‐term effects of MDMA and 3, 4‐dihydroxymethamphetamine (HHMA) on brain monoamine levels after ip or striatal … • Ecstasy (MDMA) deaths in New York City: a case series and review of the literature • Serotonin (1A) receptor involvement in acute 3, 4-methylenedioxymethamphetamine (MDMA) facilitation of social interaction in the rat • Elevated impulsivity and impaired decision-making in abstinent Ecstasy (MDMA) users compared to polydrug and drug-naive controls • A comparison of the reinforcing efficacy of 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”) with cocaine in rhesus monkeys • Dissociable effects of a single dose of ecstasy (MDMA) on psychomotor skills and attentional performance • Self-reported psychopathological symptoms in recreational ecstasy (MDMA) users are mainly associated with regular cannabis use: further evidence from a combined … • MDMA, serotonergic neurotoxicity, and the diverse functional deficits of recreational 'Ecstasy'users • Role of serotonin via 5-HT 2B receptors in the reinforcing effects of MDMA in mice • Functional MRI study of working memory in MDMA users • Behavioral and neurochemical effects of prenatal methylenedioxymethamphetamine (MDMA) exposure in rats • Direct effects of 3, 4‐methylenedioxymethamphetamine (MDMA) on serotonin or dopamine release and uptake in the caudate putamen, nucleus accumbens … • 3, 4-Methylenedioxymethamphetamine (MDMA, ecstasy) and driving impairment • Effect of Repeated ('Binge') Dosing of MDMA to Rats Housed at Normal and High Temperature on Neurotoxicdamage to Cerebral 5-Ht and Dopamine Neurones • Psychiatric disorders in Ecstasy (MDMA) users: a literature review focusing on personal predisposition and drug history • Acute toxicity of 3, 4-methylenedioxymethamphetamine (MDMA) in Sprague–Dawley and Dark Agouti rats • Death rates from ecstasy (MDMA, MDA) and polydrug use in England and Wales 1996–2002 • Effects of dopamine D1- or D2-like receptor antagonists on the hypermotive and discriminative stimulus effects of (+)-MDMA • The neuropsychology of ecstasy (MDMA) use: a quantitative review • Is a single dose of MDMA harmless • MDMA: its history and pharmacology • Rewarding effects and reinstatement of MDMA-induced CPP in adolescent mice • Acute and long-term consequences of single MDMA administration in relation to individual anxiety levels in the rat • Fatal poisoning by MDMA (ecstasy) and MDEA: a case report • High intensity dependence of auditory evoked dipole source activity indicates decreased serotonergic activity in abstinent ecstasy (MDMA) users • MDMA and temperature: a review of the thermal effects of 'Ecstasy'in humans • Simultaneous analysis of six amphetamines and analogues in hair, blood and urine by LC-ESI-MS/MS: application to the determination of MDMA after low Ecstasy … • Decreased social behaviour following 3, 4-methylenedioxymethamphetamine (MDMA) is accompanied by changes in 5-HT2A receptor responsivity • A contribution to the chemical profiling of 3, 4-methylenedioxymethamphetamine (MDMA) tablets • Repeated weekly exposure to MDMA, methamphetamine or their combination: long-term behavioural and neurochemical effects in rats • Administration of SCH 23390 into the medial prefrontal cortex blocks the expression of MDMA-induced behavioral sensitization in rats: an effect mediated by 5 … • The therapeutic use of MDMA • Distinct acute effects of LSD, MDMA, and D-amphetamine in healthy subjects • A study of the mechanism of MDMA ('Ecstasy')‐induced neurotoxicity of 5‐HT neurones using chlormethiazole, dizocilpine and other protective compounds • Relevance of MDMA (" ecstasy")-induced neurotoxicity to long-lasting psychomotor stimulation in mice • Gender differences in self-reported anxiety, depression, and somatization among ecstasy/MDMA polydrug users, alcohol/tobacco users, and nondrug users • Stability study of the designer drugs “MDA, MDMA and MDEA” in water, serum, whole blood, and urine under various storage temperatures • Neuroimaging findings with MDMA/ecstasy: technical aspects, conceptual issues and future prospects • Psychomotor stimulant effects ofd-amphetamine, MDMA and PCP: aggressive and schedule-controlled behavior in mice • Effects of acute MDMA intoxication on mood and impulsivity: role of the 5-HT 2 and 5-HT 1 receptors • Studies on the effect of MDMA ('ecstasy') on the body temperature of rats housed at different ambient room temperatures • Loss of serotonin transporter protein after MDMA and other ring-substituted amphetamines • The anxiogenic-like and anxiolytic-like effects of MDMA on mice in the elevated plus-maze: a comparison with amphetamine • Neuropsychological effects of 3, 4-methylenedioxymethamphetamine (MDMA or ecstasy) in recreational users • Chemical profiling of 3, 4-methylenedioxymethamphetamine (MDMA) tablets seized in Hong Kong • Effect of MDMA neurotoxicity upon its conditioned place preference and discrimination • Repeated MDMA (“ecstasy”) exposure in adolescent male rats alters temperature regulation, spontaneous motor activity, attention, and serotonin transporter binding • MDMA-assisted therapy: a new treatment model for social anxiety in autistic adults • Treating posttraumatic stress disorder with MDMA-assisted psychotherapy: a preliminary meta-analysis and comparison to prolonged exposure therapy • Exposure to 3, 4-methylenedioxymethamphetamine (MDMA) on postnatal days 11–20 induces reference but not working memory deficits in the Morris water maze in … • Brain concentrations of d-MDMA are increased after stress • Structure-activity relationship of MDMA and related compounds: A new class of psychoactive drugs? • A reliable model of intravenous MDMA self-administration in naive mice • Psychological profile of abstinent recreational Ecstasy (MDMA) users and significance of concomitant cannabis use • Discriminative profile of MDMA • Pill content, dose and resulting plasma concentrations of 3, 4‐methylendioxymethamphetamine (MDMA) in recreational 'ecstasy'users • Nantenine: an antagonist of the behavioral and physiological effects of MDMA in mice • Differential effects of intravenous R, S‐(±)‐3, 4‐methylenedioxymethamphetamine (MDMA, Ecstasy) and its S (+)‐and R (−)‐enantiomers on dopamine transmission … • Effects of cortical serotonin depletion induced by 3, 4-methylenedioxymethamphetamine (MDMA) on behavior, before and after additional cholinergic blockade • An exploration of the history and controversies surrounding MDMA and MDA • Changes in serotonin, dopamine and noradrenaline levels in striatum and nucleus accumbens after repeated administration of the abused drug MDMA in rats • A review of 3, 4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy • Dopamine D2-receptor knockout mice are protected against dopaminergic neurotoxicity induced by methamphetamine or MDMA • Mechanism of 3, 4‐methylenedioxymethamphetamine (MDMA, ecstasy)‐mediated mitochondrial dysfunction in rat liver • Oral administration of 3, 4-methylenedioxymethamphetamine (MDMA) produces selective serotonergic depletion in the nonhuman primate • Neuropsychiatric manifestations following the use of 3, 4-methylenedioxymethamphetamine (MDMA:" Ecstasy"). • Acute dose of MDMA (75 mg) impairs spatial memory for location but leaves contextual processing of visuospatial information unaffected • Investigation of the prejunctional α2‐adrenoceptor mediated actions of MDMA in rat atrium and vas deferens • Study of the behavioural responses related to the potential addictive properties of MDMA in mice • MDA-MDMA concentrations in urine specimens • In vivo imaging of cerebral serotonin transporter and serotonin2A receptor binding in 3, 4-methylenedioxymethamphetamine (MDMA or “ecstasy”) and hallucinogen … • Interpretation of a 3, 4-methylenedioxymethamphetamine (MDMA) blood level: discussion by means of a distribution study in two fatalities • Cardiovascular and sympathetic responses and reflex changes elicited by MDMA • Fast LC–MS/MS method for the determination of amphetamine, methamphetamine, MDA, MDMA, MDEA, MBDB and PMA in urine • Functional consequences of repeated (±) 3, 4-methylenedioxymethamphetamine (MDMA) treatment in rhesus monkeys • Visuospatial memory impairments in users of MDMA ('ecstasy') • Ecstasy (MDMA, MDA, MDEA, MBDB) consumption, seizures, related offences, prices, dosage levels and deaths in the UK (1994–2003) • Acute 3, 4-methylenedioxymethamphetamine (MDMA) administration produces a rapid and sustained suppression of immune function in the rat • Modeling in vitro inhibition of butyrylcholinesterase using molecular docking, multi-linear regression and artificial neural network approaches • Developmental 3, 4-methylenedioxymethamphetamine (MDMA) impairs sequential and spatial but not cued learning independent of growth, litter effects or injection … • Multifaceted empathy of healthy volunteers after single doses of MDMA: a pooled sample of placebo-controlled studies • Cerebral activation in abstinent ecstasy (MDMA) users during a working memory task: a functional magnetic resonance imaging (fMRI) study • The potential dangers of using MDMA for psychotherapy • Neurocognitive function in users of MDMA: the importance of clinically significant patterns of use • MDMA‐induced neurotoxicity: long‐term effects on 5‐HT biosynthesis and the influence of ambient temperature • Therapeutic effect of increased openness: Investigating mechanism of action in MDMA-assisted psychotherapy • Early loss of dopaminergic terminals in striosomes after MDMA administration to mice • Tissue concentrations of MDMA and its metabolite MDA in three fatal cases of overdose • Impurity profiling of seized MDMA tablets by capillary gas chromatography • The neurotoxic effects of 3, 4-methylenedioxymethamphetamine (MDMA) and methamphetamine on serotonin, dopamine, and GABA-ergic terminals: an in-vitro … • … of a single dose of 3, 4-methylenedioxymethamphetamine on circadian patterns, motor activity and sleep in drug-naive rats and rats previously exposed to MDMA • A case of MAO inhibitor/MDMA interaction: agony after ecstasy • MDMA and PTSD treatment:“PTSD: from novel pathophysiology to innovative therapeutics” • Cognitive performance of MDMA-treated rhesus monkeys: sensitivity to serotonergic challenge • Immunomodulating activity of MDMA • Genetic deletion of trace amine 1 receptors reveals their role in auto-inhibiting the actions of ecstasy (MDMA) • Sex differences in the effects of MDMA (ecstasy) on plasma copeptin in healthy subjects • Effects of MDMA, MDA and MDEA on blood pressure, heart rate, locomotor activity and body temperature in the rat involve α‐adrenoceptors • Enhancement of conditioned place preference response to cocaine in rats following subchronic administration of 3, 4‐methylenedioxymethamphetamine (MDMA) • Investigation of serotonin-1A receptor function in the human psychopharmacology of MDMA • Confirmation of amphetamine, methamphetamine, MDA and MDMA in urine samples using disk solid-phase extraction and gas chromatography–mass spectrometry … • Concentrations and ratios of amphetamine, methamphetamine, MDA, MDMA, and MDEA enantiomers determined in plasma samples from clinical toxicology and … • Near-fatal hyponatraemic coma due to vasopressin over-secretion after" ecstasy"(3, 4-MDMA) • MDMA study • Fatal MDMA intoxication • Recreational use of MDMA • Prospective memory impairment in “ecstasy”(MDMA) users • Memory impairment in now abstinent MDMA users and continued users: a longitudinal follow-up • MDMA self-administration in laboratory animals: a summary of the literature and proposal for future research • Toxicity of methylenedioxymethamphetamine (MDMA) in the dog and the rat • Mechanisms of MDMA (ecstasy)-induced oxidative stress, mitochondrial dysfunction, and organ damage • Pre-exposure to (±) 3, 4-methylenedioxy-methamphetamine (MDMA) facilitates acquisition of intravenous cocaine self-administration in rats • MDMA (ecstasy) pharmacokinetics in a CYP2D6 poor metaboliser and in nine CYP2D6 extensive metabolisers • Acquisition of MDMA self‐administration: pharmacokinetic factors and MDMA‐induced serotonin release • Investigating the potential neurotoxicity of Ecstasy (MDMA): an imaging approach • Verbal working memory deficits in current and previous users of MDMA • Use of amphetamine by recreational users of ecstasy (MDMA) is associated with reduced striatal dopamine transporter densities: a β-CIT SPECT study … • Endocannabinoids and 3, 4-methylenedioxymethamphetamine (MDMA) interaction • Carvedilol inhibits the cardiostimulant and thermogenic effects of MDMA in humans • Effects of MPEP on expression of food‐, MDMA‐or amphetamine‐conditioned place preference in rats • MDMA as a discriminative stimulus: isomeric comparisons • Behavioral and neurochemical effects of chronic methylenedioxymethamphetamine (MDMA) treatment in rhesus monkeys • Effects of (±) 3, 4-methylenedioxymethamphetamine (MDMA) on sleep and circadian rhythms • Executive function in abstinent MDMA (ecstasy') users • Serotonin release contributes to the locomotor stimulant effects of 3, 4-methylenedioxymethamphetamine in rats. • Effects of MDMA on complex brain function in laboratory animals • The ugly side of amphetamines: short-and long-term toxicity of 3, 4-methylenedioxymethamphetamine (MDMA,'Ecstasy'), methamphetamine and D-amphetamine • Sweat Testing of MDMA with the Drugwipe® Analytical Device: A Controlled Study with Two Volunteers • Is there a case for MDMA-assisted psychotherapy in the UK? • Brain serotonin function in MDMA (ecstasy) users: evidence for persisting neurotoxicity • Effects of (±) 3, 4-methylenedioxymethamphetamine (MDMA) on brain dopaminergic activity in rats • Usefulness of sweat testing for the detection of MDMA after a single-dose administration • Repeated administration of MDMA causes transient down-regulation of serotonin 5-HT2 receptors • Risperidone attenuates and reverses hyperthermia induced by 3, 4-methylenedioxymethamphetamine (MDMA) in rats • … hot on Ecstasy: physical activity and thermal comfort ratings are associated with the memory and other psychobiological problems reported by recreational MDMA … • The prosocial effects of 3, 4-methylenedioxymethamphetamine (MDMA): controlled studies in humans and laboratory animals • Carvedilol reverses hyperthermia and attenuates rhabdomyolysis induced by 3, 4-methylenedioxymethamphetamine (MDMA, Ecstasy) in an animal model • The effect of acutely administered MDMA on subjective and BOLD-fMRI responses to favourite and worst autobiographical memories • Behavioural and neurochemical comparison of chronic intermittent cathinone, mephedrone and MDMA administration to the rat • Relevance of rodent models of intravenous MDMA self-administration to human MDMA consumption patterns • Simultaneous analysis of amphetamine, methamphetamine, and 3, 4-methylenedioxymethamphetamine (MDMA) in urine samples by solid-phase extraction … • Using MDMA in psychotherapy. • … assay for enantioselective measurement of the designer drugs MDEA, MDMA, and MDA and its application to samples from a controlled study with MDMA • Neural correlates of working memory in pure and polyvalent ecstasy (MDMA) users • MDMA: interactions with other psychoactive drugs • Ecstasy: the clinical, pharmacological and neurotoxicological effects of the drug MDMA • Development and characterization of a novel animal model of intermittent MDMA (“Ecstasy”) exposure during adolescence • MDMA ('ecstasy') exhibits an anxiogenic-like activity in social encounters between male mice • Acute effects of nocturnal doses of MDMA on measures of impulsivity and psychomotor performance throughout the night • … , 4-methylenedioxyphenyl)-2-aminopropane (MDE) and N-hydroxy-1-(3, 4-methylenedioxyphenyl)-2-aminopropane (N-OH MDA) in rats trained to discriminate MDMA … • d-MDMA during vitamin E deficiency: effects on dopaminergic neurotoxicity and hepatotoxicity • 3, 4-methylenedioxymethamphetamine (MDMA): current perspectives • Methysergide potentiates the hyperactivity produced by MDMA in rats • Memory performance in polyvalent MDMA (ecstasy) users who continue or discontinue MDMA use • Acute and subchronic effects of MDMA (“ecstasy”) on anxiety in male mice tested in the elevated plus-maze • Rediscovering MDMA (ecstasy): the role of the American chemist Alexander T. Shulgin • Chiral separation and quantification of R/S-amphetamine, R/S-methamphetamine, R/S-MDA, R/S-MDMA, and R/S-MDEA in whole blood by GC-EI-MS • MDMA, methamphetamine and their combination: possible lessons for party drug users from recent preclinical research • Discriminative stimulus effects of 3, 4-methylenedioxymethamphetamine (MDMA) in humans trained to discriminate among d-amphetamine, meta … • Drug use practices among MDMA/ecstasy users in Ohio: a latent class analysis • Breakthrough for trauma treatment: safety and efficacy of MDMA-assisted psychotherapy compared to paroxetine and sertraline • Investigation of MDMA-related agents in rats trained to discriminate MDMA from saline • Mortality among individuals with cannabis, cocaine, amphetamine, MDMA, and opioid use disorders: a nationwide follow-up study of Danish substance users in … • … of 3, 4-methylenedioxymethamphetamine (MDMA) enantiomers in vitro and in the MPTP-lesioned primate: R-MDMA reduces severity of dyskinesia, whereas S-MDMA … • 3, 4-Methylenedioxyethylamphetamine (MDE), a novel analogue of MDMA, produces long-lasting depletion of serotonin in the rat brain • Neural and cardiac toxicities associated with 3, 4-methylenedioxymethamphetamine (MDMA) • Attenuation of 3,4‐methylenedioxymethamphetamine (MDMA, Ecstasy)‐induced rhabdomyolysis with α1‐ plus β3‐adrenoreceptor antagonists • MDMA, politics and medical research: Have we thrown the baby out with the bathwater? • Methamphetamine and MDMA (ecstasy) neurotoxicity:'of mice and men' • Action of MDMA (ecstasy) and its metabolites on arginine vasopressin release • p-Chloroamphetamine (PCA), 3,4-methylenedioxymethamphetamine (MDMA) andd-fenfluramine pretreatment attenuatesd-fenfluramine-evoked release of 5-HT in … • Is vitreous humour useful for the interpretation of 3, 4-methylenedioxymethamphetamine (MDMA) blood levels? • MDMA and fenfluramine reduce L‐DOPA‐induced dyskinesia via indirect 5‐HT1A receptor stimulation • Direct comparison of the acute subjective, emotional, autonomic, and endocrine effects of MDMA, methylphenidate, and modafinil in healthy subjects • Problematic versus non-problematic ecstasy/MDMA use: the influence of drug usage patterns and pre-existing psychiatric factors • Evidence that both intragastric and subcutaneous administration of methylenedioxymethylamphetamine (MDMA) produce serotonin neurotoxicity in rhesus monkeys • Short-and long-term effects of MDMA (“ecstasy”) on synaptosomal and vesicular uptake of neurotransmitters in vitro and ex vivo • The effect of optical isomers of 3, 4-methylenedioxymethamphetamine (MDMA) on stereotyped behavior in rats • Effects of MDMA alone and after pretreatment with reboxetine, duloxetine, clonidine, carvedilol, and doxazosin on pupillary light reflex • History of MDMA • MDMA induced hyperthermia: a survivor with an initial body temperature of 42.9 degrees C. • Ecstasy (MDMA) and memory function: a meta‐analytic update • Effects of 3, 4-methylenedioxy-methamphetamine (MDMA) on anxiety in mice tested in the light-dark box • Partial lesion of the serotonergic system by a single dose of MDMA results in behavioural disinhibition and enhances acute MDMA-induced social behaviour on the … • A three-choice discrimination procedure dissociates the discriminative stimulus effects of d-amphetamine and (±)-MDMA in rats. • Neurotoxic effects of MDMA (“ecstasy”) administration to neonatal rats • Methylenedioxymethamphetamine (MDMA)-related fatalities in Australia: demographics, circumstances, toxicology and major organ pathology • Comparative effects of substituted amphetamines (PMA, MDMA, and METH) on monoamines in rat caudate: a microdialysis study • Neurobehavioral outcomes of infants exposed to MDMA (Ecstasy) and other recreational drugs during pregnancy • The effect of MDMA (“Ecstasy”) and its optical isomers on schedule-controlled responding in mice • Effects of phencyclidine, ketamine and MDMA on complex operant behavior in monkeys • Subjective ratings of prospective memory deficits in MDMA ('ecstasy') users • Effects of ecstasy (MDMA) on the brain in abstinent users: initial observations with diffusion and perfusion MR imaging • MDMA: on the translation from rodent to human dosing • Characteristics and trends of 3, 4-methylenedioxymethamphetamine (MDMA) tablets found in Taiwan from 2002 to February 2005 • Post-mortem redistribution of 3, 4-methylenedioxymethamphetamine (MDMA," ecstasy") in the rabbit. Part II: post-mortem infusion in trachea or stomach. • In vivo evidence against clomethiazole being neuroprotective against MDMA ('ecstasy')-induced degeneration of rat brain 5-HT nerve terminals by a free radical … • THC prevents MDMA neurotoxicity in mice • … for drug abuse XV. Disposition of 3, 4-methylenedioxymethamphetamine (MDMA) and its related compounds into rat hair and application to hair analysis for MDMA … • Role of brain nitric oxide in (±) 3, 4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity in rats • Proton magnetic resonance spectroscopy in ecstasy (MDMA) users • DNA damage and ubiquitinated neuronal inclusions in the substantia nigra and striatum of mice following MDMA (ecstasy) • Inhibition of MAO-B protects against MDMA-induced neurotoxicity in the striatum • Behavioural and neurochemical effects of combined MDMA and THC administration in mice • MDMA-like behavioral effects of N-substituted piperazines in the mouse • MDMA produces stimulant-like conditioned locomotor activity • Ecstasy (MDMA) mimics the post-orgasmic state: impairment of sexual drive and function during acute MDMA-effects may be due to increased prolactin secretion • No evidence that MDMA-induced enhancement of emotional empathy is related to peripheral oxytocin levels or 5-HT 1a receptor activation • Involvement of inferior parietal lobules in prospective memory impairment during acute MDMA (ecstasy) intoxication: an event-related fMRI study • Multiple molecular and neuropharmacological effects of MDMA (Ecstasy) • Chronic exposure to ethanol exacerbates MDMA-induced hyperthermia and exposes liver to severe MDMA-induced toxicity in CD1 mice • Methylenedioxymethamphetamine (MDMA; Ecstasy) suppresses IL-1β and TNF-α secretion following an in vivo lipopolysaccharide challenge • Use of MDA (the" love drug") and methamphetamine in Toronto by unsuspecting users of ecstasy (MDMA) • MDMA decreases the effects of simulated social rejection • Evidence for a role of energy dysregulation in the MDMA-induced depletion of brain 5-HT • Plasma oxytocin concentrations following MDMA or intranasal oxytocin in humans • MDMA, methamphetamine, and CYP2D6 pharmacogenetics: what is clinically relevant? • Multiple MDMA (Ecstasy) overdoses at a rave event: a case series • Human pharmacology of mephedrone in comparison with MDMA • Drug intelligence based on MDMA tablets data: 2. Physical characteristics profiling • The effects of repeated administration of MDMA on the expression of sexual behavior in the male rat • Adverse symptomatology and suicide associated with the use of methylenedioxymethamphetamine (MDMA; Ecstasy) • A study of impurities in intermediates and 3, 4-methylenedioxymethamphetamine (MDMA) samples produced via reductive amination routes • Structure-activity relationships of MDMA-like substances • Integration of GC/EI-MS and GC/NCI-MS for simultaneous quantitative determination of opiates, amphetamines, MDMA, ketamine, and metabolites in human hair • MDMA and 5‐HT neurotoxicity: the empirical evidence for its adverse effects in humans–no need for translation • Adam (MDMA) and Eve (MDEA) misuse: an immunohistochemical study on three fatal cases • Acute effects of dexfenfluramine (d‐FEN) and methylenedioxymethamphetamine (MDMA) before and after short‐course, high‐dose treatment • A developmental comparison of the neurobehavioral effects of ecstasy (MDMA) • The preclinical pharmacology of mephedrone; not just MDMA by another name • Determination of MDMA, MDA, MDEA and MBDB in oral fluid using high performance liquid chromatography with native fluorescence detection • Long-term central 5-HT depletions resulting from repeated administration of MDMA enhances the effects of single administration of MDMA on schedule-controlled … • PRECLINICAL STUDY: Acquisition and reinstatement of MDMA‐induced conditioned place preference in mice pre‐treated with MDMA or cocaine during adolescence • One-year outcomes of prenatal exposure to MDMA and other recreational drugs • Enantiomer profiling of high loads of amphetamine and MDMA in communal sewage: a Dutch perspective • Deconstructing ecstasy: the politics of MDMA research • Elevation of serum prolactin and corticosterone concentrations in the rat after the administration of 3, 4-methylenedioxymethamphetamine. • Effects of cocaine and MDMA self-administration on serotonin transporter availability in monkeys • Dopaminergic mechanisms of reinstatement of MDMA‐seeking behaviour in rats • Vascular actions of MDMA involve α1 and α2‐adrenoceptors in the anaesthetized rat • Cytotoxic effects of 3,4-methylenedioxy-N-alkylamphetamines, MDMA and its analogues, on isolated rat hepatocytes • Effect of 3, 4-methylendioxymethamphetamine (MDMA,“ecstasy”) on dopamine transmission in the nucleus accumbens shell and core • Analysis of ecstasy (MDMA)‐induced transcriptional responses in the rat cortex • Behavioral profile of 3, 4-methylenedioxy-methamphetamine (MDMA) in agonistic encounters between male mice • Neural effects of MDMA as determined by functional magnetic resonance imaging and magnetic resonance spectroscopy in awake marmoset monkeys • Dantrolene in the treatment of MDMA-related hyperpyrexia: a systematic review • The N-methyl-D-aspartate (NMDA) receptor antagonist, dextrorphan, prevents the neurotoxic effects of 3, 4-methylenedioxymethamphetamine (MDMA) in rats • Inhibition of serotonin transporters disrupts the enhancement of fear memory extinction by 3, 4-methylenedioxymethamphetamine (MDMA) • High ambient temperature increases 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”)-induced Fos expression in a region-specific manner • Major depression: the relative contribution of gender, MDMA, and cannabis use • Role of 5-HT2A and 5-HT2C/B receptors in the acute effects of 3,4-methylenedioxymethamphetamine (MDMA) on striatal single-unit activity and locomotion in freely … • Who is 'Molly'? MDMA adulterants by product name and the impact of harm-reduction services at raves • Death from hyponatraemia-induced cerebral oedema associated with MDMA (ecstasy) use • Release of serotonin induced by 3, 4-methylenedioxymethamphetamine (MDMA) and other substituted amphetamines in cultured fetal raphe neurons: further … • MDMA administration to pregnant Sprague–Dawley rats results in its passage to the fetal compartment • Potential psychiatric uses for MDMA • Medical risks associated with MDMA use. • Monoamine metabolites in the cerebrospinal fluid of recreational users of 3, 4-methylenedimethoxymethamphetamine MDMA: Ecstasy • The effects of MDMA on socio-emotional processing: Does MDMA differ from other stimulants? • Differential effect of dietary selenium on the long-term neurotoxicity induced by MDMA in mice and rats • Increases in use of novel synthetic stimulant are not directly linked to decreased use of 3, 4-methylenedioxy-N-methylamphetamine (MDMA) • Prosocial effects of MDMA: A measure of generosity • Neurotoxicity of ecstasy (MDMA): an overview • MDMA and learning: effects of acute and neurotoxic exposure in the rat • Urinary MDMA, MDA, HMMA, and HMA excretion following controlled MDMA administration to humans • Validation of an ELISA-based screening assay for the detection of amphetamine, MDMA and MDA in blood and oral fluid • Pharmacokinetics and pharmacodynamics of 3, 4-methylenedioxymethamphetamine (MDMA): interindividual differences due to polymorphisms and drug–drug … • Biochemical effects of the monoamine neurotoxins DSP‐4 and MDMA in specific brain regions of MAO‐B‐deficient mice • Differential toxic effects of methamphetamine (METH) and methylenedioxymethamphetamine (MDMA) in multidrug-resistant (mdr1a) knockout mice • Post-mortem redistribution of 3, 4-methylenedioxymethamphetamine (MDMA," ecstasy") in the rabbit • MDMA toxicity and pathological consequences: a review about experimental data and autopsy findings • Organic impurity profiling of 3, 4-methylenedioxymethamphetamine (MDMA) tablets seized in The Netherlands. • Auditory stimuli enhance MDMA-conditioned reward and MDMA-induced nucleus accumbens dopamine, serotonin and locomotor responses • Human deaths and toxic reactions attributed to MDMA and MDEA • Acute neuropsychological effects of MDMA and ethanol (co-) administration in healthy volunteers • Sex differences in the neurochemical and functional effects of MDMA in Sprague–Dawley rats • Experimental studies on 3, 4-methylenedioxymethamphetamine (MDMA,“ecstasy”) and its potential to damage brain serotonin neurons • A genetic deletion of the serotonin transporter greatly enhances the reinforcing properties of MDMA in rats • Recreational ecstasy use and the neurotoxic potential of MDMA: current status of the controversy and methodological issues • Neural mechanisms of working memory in ecstasy (MDMA) users who continue or discontinue ecstasy and amphetamine use: evidence from an 18-month longitudinal … • … gas chromatographic–electron impact ionization mass spectrometric method for methylenedioxymethamphetamine (MDMA), methamphetamine and metabolites in … • Intravenous self-administration of mephedrone, methylone and MDMA in female rats • Long-term behavioral consequences of prenatal MDMA exposure • Memantine prevents MDMA-induced neurotoxicity • The nature of 3, 4-methylenedioxymethamphetamine (MDMA)-induced serotonergic dysfunction: evidence for and against the neurodegeneration hypothesis • Microglial and astroglial activation by 3, 4‐methylenedioxymethamphetamine (MDMA) in mice depends on S (+) enantiomer and is associated with an increase in … • MDMA (“Ecstasy”) suppresses the innate IFN-γ response in vivo: a critical role for the anti-inflammatory cytokine IL-10 • Designer drug confusion: a focus on MDMA • Headspace sampling and detection of cocaine, MDMA, and marijuana via volatile markers in the presence of potential interferences by solid phase microextraction … • Damage of serotonergic axons and immunolocalization of Hsp27, Hsp72, and Hsp90 molecular chaperones after a single dose of MDMA administration in Dark … • NMDA receptor subunit and CaMKII changes in rat hippocampus induced by acute MDMA treatment: a mechanism for learning impairment • Neural correlates of MDMA (“Ecstasy”)-induced social interaction in rats • MDMA-assisted psychotherapy for posttraumatic stress disorder: A promising novel approach to treatment • Assessment of the MDA and MDMA optical isomers in a stimulant-hallucinogen discrimination • Differential long-term effects of MDMA on the serotoninergic system and hippocampal cell proliferation in 5-HTT knock-out vs. wild-type mice • Behavioral effects of MDMA (“Ecstasy”) on adult zebrafish • Binge ethanol administration enhances the MDMA-induced long-term 5-HT neurotoxicity in rat brain • MDMA alters emotional processing and facilitates positive social interaction • Studies of MDMA-Induced Neurotoxicity in Nonhuman Primates: A Basis for Evaluating • Cardiac oxidative stress determination and myocardial morphology after a single ecstasy (MDMA) administration in a rat model • Studies on the neuroprotective effect of pentobarbitone on MDMA-induced neurodegeneration • The rewarding properties of MDMA are preserved in mice lacking µ‐opioid receptors • The effect of catecholamine depletion by alpha-methyl-para-tyrosine on measures of cognitive performance and sleep in abstinent MDMA users • Photonic switch working in momentum-division-multiple-access (MDMA) mode for microwave and optical wavelengths based upon the measurement of the spin, the … • … human liver preparations, HepaRG, or HepG2 cell lines for metabolism studies of new psychoactive substances? A study using MDMA, MDBD, butylone, MDPPP … • Endogenous 5‐HT, released by MDMA through serotonin transporter‐and secretory vesicle‐dependent mechanisms, reduces hippocampal excitatory synaptic … • Neural correlates of the severity of cocaine, heroin, alcohol, MDMA and cannabis use in polysubstance abusers: a resting-PET brain metabolism study • Self-reported prevalence of dependence of MDMA compared to cocaine, mephedrone and ketamine among a sample of recreational poly-drug users • Sleep apnea in young abstinent recreational MDMA (“ecstasy”) consumers • New age seekers: MDMA use as an adjunct to spiritual pursuit • A reconsideration and response to Parrott AC (2013)“Human psychobiology of MDMA or 'Ecstasy': an overview of 25 years of empirical research” • Treatment with MDMA from P11–20 disrupts spatial learning and path integration learning in adolescent rats but only spatial learning in older rats • Attenuation of 3, 4-methylenedioxymethamphetamine (MDMA) induced neurotoxicity with the serotonin precursors tryptophan and 5-hydroxytryptophan • Sources of information about MDMA (3, 4-methylenedioxymethamphetamine): perceived accuracy, importance, and implications for prevention among young adult … • Acute effects of 3, 4-methylenedioxymethamphetamine (MDMA) on 5-HT cell firing and release: comparison between dorsal and median raphe 5-HT systems • Role of α2A‐adrenoceptors in the effects of MDMA on body temperature in the mouse • Blockade of 5-HT 2 receptor selectively prevents MDMA-induced verbal memory impairment • Are there sex differences associated with the effects of ecstasy/3, 4-methylenedioxymethamphetamine (MDMA)? • Studies on the role of dopamine D1 receptors in the development and expression of MDMA-induced behavioral sensitization in rats • Progress and promise for the MDMA drug development program • Acute administration of 3, 4-methylenedioxymethamphetamine (MDMA) induces oxidative stress, lipoperoxidation and TNFα-mediated apoptosis in rat liver • Reinstatement of MDMA (ecstasy) seeking by exposure to discrete drug-conditioned cues • Candyflipping': synergistic discriminative effect of LSD and MDMA • Effects of priming injections of MDMA and cocaine on reinstatement of MDMA-and cocaine-seeking in rats • The influence of genetic and environmental factors among MDMA users in cognitive performance • Acute behavioural and neurotoxic effects of MDMA plus cocaine in adolescent mice • MPTP‐induced dopamine neuron degeneration and glia activation is potentiated in MDMA‐pretreated mice • MDMA and methamphetamine: some paradoxical negative and positive mood changes in an acute dose laboratory study • An antisense oligonucleotide targeted at MAO-B attenuates rat striatal serotonergic neurotoxicity induced by MDMA • Party people: Personality and MDMA use of house party visitors • Methylenedioxymethamphetamine (MDMA,“ecstasy”) • Plasma levels of parent compound and metabolites after doses of either d-fenfluramine or d-3, 4-methylenedioxymethamphetamine (MDMA) that produce long-term … • Use of MDMA and other illicit drugs by young adult males in Northern Spain • Hair MDMA samples are consistent with reported ecstasy use: findings from a study investigating effects of ecstasy on mood and memory • MDMA effects in brain: pharmacologic profile and evidence of neurotoxicity from neurochemical and autoradiographic studies • Stereochemistry of the metabolism of MDMA to MDA • Acute concomitant effects of MDMA binge dosing on extracellular 5-HT, locomotion and body temperature and the long-term effect on novel object discrimination in … • 'Ecstasy'as a social drug: MDMA preferentially affects responses to emotional stimuli with social content • Aortic dissection after ingestion of" ecstasy"(MDMA) • Ecstasy (MDMA) and oral health • Qualitative review of serotonin syndrome, ecstasy (MDMA) and the use of other serotonergic substances: hierarchy of risk • Cardiovascular autonomic dysregulation in users of MDMA (“ecstasy”) • Differential effects of MDMA and scopolamine on working versus reference memory in the radial arm maze task • Brain serotonin transporter binding in former users of MDMA ('ecstasy') • Fatality due to combined use of the designer drugs MDMA and PMA: a distribution study • Comparison of the discriminative stimulus effects of 3, 4-methylenedioxymethamphetamine (MDMA) and cocaine: asymmetric generalization • Assessing long-term effects of MDMA (Ecstasy). • High-pressure liquid chromatography/electrochemical detection method for monitoring MDA and MDMA in whole blood and other biological tissues • MDMA effects consistent across laboratories • MDMA and seizures: a dangerous liaison? • … (MDMA) on serotonin transporter and vesicular monoamine transporter 2 protein and gene expression in rats: implications for MDMA neurotoxicity • Ecstasy/MDMA and cannabis: the complexities of their interactive neuropsychobiological effects • A prospective study of learning, memory, and executive function in new MDMA users • Calpain and caspase proteolytic markers co-localize with rat cortical neurons after exposure to methamphetamine and MDMA • Ecstasy (MDMA), amphetamine, and LSD: Comparative mood profiles in recreational polydrug users • Drug seeking in response to a priming injection of MDMA in rats: relationship to initial sensitivity to self-administered MDMA and dorsal striatal dopamine • MDMA-induced c-Fos expression in oxytocin-containing neurons is blocked by pretreatment with the 5-HT-1A receptor antagonist WAY 100635 • α1-Adrenergic receptors mediate the locomotor response to systemic administration of (±)-3, 4-methylenedioxymethamphetamine (MDMA) in rats • Metabolites of MDMA induce oxidative stress and contractile dysfunction in adult rat left ventricular myocytes • Fluoxetine pretreatment effects pharmacokinetics of 3, 4‐methylenedioxymethamphetamine (MDMA, ECSTASY) in rat • A study on the mechanisms by which minocycline protects against MDMA ('ecstasy')-induced neurotoxicity of 5-HT cortical neurons • MDMA in Adolescent Male Rats: Decreased Serotonin in the Amygdala and Behavioral Effects in the Elevated Plus‐Maze Test • MDMA and fenfluramine alter the response of the circadian clock to a serotonin agonist in vitro • Protection against MDMA-induced dopaminergic neurotoxicity in mice by methyllycaconitine: involvement of nicotinic receptors • Differential response of nNOS knockout mice to MDMA (“ecstasy”)‐and methamphetamine‐induced psychomotor sensitization and neurotoxicity • Chronic exposure to MDMA (Ecstasy) elicits behavioral sensitization in rats but fails to induce cross-sensitization to other psychostimulants • Study on the neuroprotective effect of fluoxetine against MDMA-induced neurotoxicity on the serotonin transporter in rat brain using micro-PET • … –nonenzymatic cellular antioxidant defense systems response and immunohistochemical detection of MDMA, VMAT2, HSP70, and apoptosis as biomarkers for MDMA … • Enantiomeric Separation and Quantitation of (±)-Amphetamine,(±)-Methamphetamine,(±)-MDA,(±)-MDMA, and (±)-MDEA in Urine Specimens by GC-EI-MS after … • Determination of MDMA, MDEA and MDA in urine by high performance liquid chromatography with fluorescence detection • … and spectroscopic characterisation of amphetamine-like drugs: application to the screening of 3, 4-methylenedioxymethamphetamine (MDMA) and its synthetic … • (±) 3, 4-Methylenedioxymethamphetamine (MDMA) produces long-term reductions in brain 5-hydroxytryptamine in rats • Involvement of D1 dopamine receptor in MDMA-induced locomotor activity and striatal gene expression in mice • A pure amnestic syndrome after MDMA (" ecstasy") ingestion. • MDMA increases glutamate release and reduces parvalbumin-positive GABAergic cells in the dorsal hippocampus of the rat: role of cyclooxygenase • Critical role of peripheral vasoconstriction in fatal brain hyperthermia induced by MDMA (Ecstasy) under conditions that mimic human drug use • Neurotoxicity and persistent cognitive deficits induced by combined MDMA and alcohol exposure in adolescent rats • Chronic treatment with supraphysiological levels of corticosterone enhances D-MDMA-induced dopaminergic neurotoxicity in the C57BL/6J female mouse • MDMA and memory: the acute and chronic effects of MDMA in pigeons performing under a delayed-matching-to-sample procedure • Self-reported ecstasy/MDMA/“Molly” use in a sample of nightclub and dance festival attendees in New York City • Repeated adolescent 3, 4-methylenedioxymethamphetamine (MDMA) exposure in rats attenuates the effects of a subsequent challenge with MDMA or a 5 … • MDMA “ecstasy” alters hyperactive and perseverative behaviors in dopamine transporter knockout mice • Association of caffeine to MDMA does not increase antinociception but potentiates adverse effects of this recreational drug • MDMA and MDA concentrations in antemortem and postmortem specimens in fatalities following hospital admission • Elemental analysis of 3, 4-methylenedioxymethamphetamine (MDMA): A tool to determine the synthesis method and trace links • Glucocorticoids and 3, 4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity • Prospective associations between meth/amphetamine (speed) and MDMA (ecstasy) use and depressive symptoms in secondary school students • MDMA on the street: Analysis Anonymous® • Sub-chronic nandrolone treatment modifies neurochemical and behavioral effects of amphetamine and 3, 4-methylenedioxymethamphetamine (MDMA) in rats • Forensic electrochemistry: simultaneous voltammetric detection of MDMA and its fatal counterpart “Dr Death”(PMA) • Different likelihood ratio approaches to evaluate the strength of evidence of MDMA tablet comparisons • Evidence that MDMA ('ecstasy') increases cannabinoid CB2 receptor expression in microglial cells: role in the neuroinflammatory response in rat brain • The origin of MDMA ('ecstasy')–separating the facts from the myth • … of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: similarities to 3, 4-(methylenedioxy) methamphetamine (MDMA) • Sensitive gas chromatography-mass spectrometry method for simultaneous measurement of MDEA, MDMA, and metabolites HMA, MDA, and HMMA in human urine • Structure-activity relationships of MDMA and related compounds: A new class of psychoactive agents? • Mephedrone does not damage dopamine nerve endings of the striatum, but enhances the neurotoxicity of methamphetamine, amphetamine, and MDMA • MDMA exposure alters cognitive and electrophysiological sensitivity to rapid tryptophan depletion in rhesus monkeys • Application of the Syva EMIT and Abbott TDx amphetamine immunoassays to the detection of 3, 4-methylenedioxymethamphetamine (MDMA) and 3, 4 … • Single dose of MDMA causes extensive decrement of serotoninergic fibre density without blockage of the fast axonal transport in Dark Agouti rat brain and spinal cord • … of (±) 3, 4-methylenedioxymethamphetamine (MDMA,“Ecstasy”) and its major metabolites in squirrel monkeys at plasma concentrations of MDMA that develop after … • Effects of the endogenous PPAR‐α agonist, oleoylethanolamide on MDMA‐induced cognitive deficits in mice • Determination of synthesis route of 1-(3, 4-methylenedioxyphenyl)-2-propanone (MDP-2-P) based on impurity profiles of MDMA • Effect of the CB1 cannabinoid agonist WIN 55212-2 on the acquisition and reinstatement of MDMA-induced conditioned place preference in mice • Ecstasy (MDMA): effects and patterns of use reported by users in Sao Paulo • Serotonergic modulation of 3, 4-methylenedioxymethamphetamine (MDMA)-elicited reduction of response rate but not rewarding threshold in accumbal self … • Adolescent pre‐exposure to ethanol and 3, 4‐methylenedioxymethylamphetamine (MDMA) increases conditioned rewarding effects of MDMA and drug‐induced … • The effect of MDA and MDMA (“Ecstasy”) isomers in combination with pirenpirone on operant responding in mice • MDMA/Ecstasy use among young people in Ohio: Perceived risk and barriers to intervention • Ethanol increases the distribution of MDMA to the rat brain: possible implications in the ethanol-induced potentiation of the psychostimulant effects of MDMA • PRECLINICAL STUDY: Changes in leptin, ghrelin, growth hormone and neuropeptide‐Y after an acute model of MDMA and methamphetamine exposure in rats • … of 3, 4‐Methylenedioxyethamphetamine (MDEA,“Eve”) on Body Temperature and Long Term Degeneration of 5‐HT Neurones in Brain: A Comparison with MDMA (“ … • 3, 4-Methylenedioxymethamphetamine (" ecstasy") selectively destroys brain serotonin terminals in rhesus monkeys. • MDMA‐evoked changes in raclopride and NMSP binding in living pig brain • Adolescent pre-exposure to ethanol or MDMA prolongs the conditioned rewarding effects of MDMA • … sensitive semi-micro column HPLC method with peroxyoxalate chemiluminescence detection and column switching for determination of MDMA-related compounds in … • On the anxiogenic and anxiolytic nature of long-term cerebral 5-HT depletion following MDMA. • Hallucinogenic and stimulatory amphetamine derivatives: fingerprinting DOM, DOI, DOB, MDMA, and MBDB by spectral analysis of brain field potentials in the freely … • Effects of alcohol (BAC 0.5‰) and ecstasy (MDMA 100 mg) on simulated driving performance and traffic safety • Microdialysis studies on 3, 4-methylenedioxymethamphetamine-induced dopamine release: effect of dopamine uptake inhibitors. • Can MDMA play a role in the treatment of substance abuse? • Human pharmacology of 3, 4-methylenedioxymethamphetamine (MDMA, ecstasy) after repeated doses taken 2 h apart • 3, 4-methylenedioxymethamphetamine (MDMA, ecstasy)-mediated production of hydrogen peroxide in an in vitro model: the role of dopamine, the serotonin-reuptake … • Attenuation of alcohol consumption by MDMA (ecstasy) in two strains of alcohol-preferring rats • Fatal MDMA intoxication • Interactions between ethanol and cocaine, amphetamine, or MDMA in the rat: thermoregulatory and locomotor effects • Development and validation of a disk solid phase extraction and gas chromatography–mass spectrometry method for MDMA, MDA, HMMA, HMA, MDEA … • Validity of β‐CIT SPECT in detecting MDMA‐induced serotonergic neurotoxicity • Context‐dependent behavioural and neuronal sensitization in striatum to MDMA (ecstasy) administration in rats • Event-related potentials (ERPs) in ecstasy (MDMA) users during a visual oddball task • Morbidity associated with MDMA (ecstasy) abuse: a survey of emergency department admissions • MDMA alters the response of the circadian clock to a photic and non-photic stimulus • Neuroimaging in human MDMA (Ecstasy) users: A cortical model • Ecstasy (MDMA), methamphetamine, and date rape (drug-facilitated sexual assault): a consideration of the issues • … of prelimbic and infralimbic medial prefrontal cortex in discrete cue-induced reinstatement of 3, 4-methylenedioxymethamphetamine (MDMA; ecstasy) seeking in rats • Sprague–Dawley rats display metabolism-mediated sex differences in the acute toxicity of 3, 4-methylenedioxymethamphetamine (MDMA, ecstasy) • Co-administration of THC and MDMA ('ecstasy') synergistically disrupts memory in rats • Initial deficit and recovery of function after MDMA preexposure in rats • Methylenedioxymethamphetamine (MDMA;'Ecstasy') suppresses antigen specific IgG2a and IFN-γ production • Role of endogenous dopamine in the central serotonergic deficits induced by 3, 4-methylenedioxymethamphetamine. • The detection of novel stimulants in oral fluid from users reporting ecstasy, Molly and MDMA ingestion • Inappropriate antidiuretic hormone secretion and extreme rises in serum creatinine kinase following MDMA ingestion. • The effects of 3, 4-methylenedioxymethamphetamine (MDMA) on nicotinic receptors: intracellular calcium increase, calpain/caspase 3 activation, and functional … • The effects of MDMA pretreatment on the behavioural effects of other drugs of abuse in the rat elevated plus-maze test • Repeated exposure to MDMA provides neuroprotection against subsequent MDMA-induced serotonin depletion in brain • Executive working memory deficits in abstinent ecstasy/MDMA users: a critical review • MDMA (ecstacy): Useful information for health professionals involved in drug education programs • Contribution of impulsivity and novelty‐seeking to the acquisition and maintenance of MDMA self‐administration • Effects of acute 3, 4-methylenedioxymethamphetamine on sleep and daytime sleepiness in MDMA users: a preliminary study • Basic and neutral route specific impurities in MDMA prepared by different synthesis methods: comparison of impurity profiles • Direct screening of urine for MDMA and MDA by liquid chromatography-tandem mass spectrometry • MDMA (ecstasy) • Cocaine, metamfetamine, and MDMA abuse: the role and clinical importance of neuroadaptation • … –mass spectrometry assay for enantioselective measurement of amphetamines in oral fluid: application to a controlled study with MDMA and driving under the … • Users' perceptions of the risks and effects of taking ecstasy (MDMA): a questionnaire study • Discriminative stimulus effects of psychostimulants and hallucinogens in S (+)-3, 4-methylenedioxymethamphetamine (MDMA) and R (−)-MDMA trained mice • Disposition of MDMA and metabolites in human sweat following controlled MDMA administration • Hyperthermic and neurotoxic effect of 3, 4-methylenedioxymethamphetamine (MDMA) in guinea pigs • MDMA administration during adolescence exacerbates MPTP-induced cognitive impairment and neuroinflammation in the hippocampus and prefrontal cortex • Bilateral sixth nerve palsy associated with MDMA (“ecstasy”) abuse • MDMA (“ecstasy”) abuse as an example of dopamine neuroplasticity • Mental disorders in current and former heavy ecstasy (MDMA) users • Repeated intermittent MDMA binges reduce DAT density in mice and SERT density in rats in reward regions of the adolescent brain • The role of 5-HT in the impairment of thermoregulation observed in rats administered MDMA ('ecstasy') when housed at high ambient temperature • Relation of sex and estrous phase to deficits in prepulse inhibition of the startle response induced by ecstasy (MDMA) • Neuroimaging of chronic MDMA (“ecstasy”) effects: A meta-analysis • Synthesis, in vitro formation, and behavioural effects of glutathione regioisomers of alpha-methyldopamine with relevance to MDA and MDMA (ecstasy) • Characterization of the Translocation of Protein Kinase C (PKC) by 3, 4-methylenedioxymethamphetamine (MDMA/Ecstasy) in Synaptosomes:: Evidence for a … • MDMA induces caspase‐3 activation in the limbic system but not in striatum • The profiling of MDMA tablets: a study of the combination of physical characteristics and organic impurities as sources of information • The variety of ecstasy/MDMA users: results from the National Epidemiologic Survey on alcohol and related conditions • Why MDMA therapy for alcohol use disorder? And why now? • Current perspective on MDMA-assisted psychotherapy for posttraumatic stress disorder • The acute and sub-acute effects of 'ecstasy'(MDMA) on processing of facial expressions: preliminary findings • Chronic paranoid psychosis after misuse of MDMA. • Evidence for executive deficits among users of MDMA (Ecstasy) • EMIT-dau monoclonal amphetamine/methamphetamine assay. II. Detection of methylenedioxyamphetamine (MDA) and methylenedioxymethamphetamine (MDMA) • Activation of protein kinase C (PKC) by 3, 4-methylenedioxymethamphetamine (MDMA) occurs through the stimulation of serotonin receptors and transporter • … mapping shows that serotonin rather than dopamine receptor mRNA expressions are affected after repeated intermittent administration of MDMA in rat brain • MDMA assisted psychotherapy found to have a large effect for chronic post-traumatic stress disorder • Memory impairment and hippocampus specific protein oxidation induced by ethanol intake and 3, 4‐Methylenedioxymethamphetamine (MDMA) in mice • Efficacy of 3, 4-methylenedioxymethamphetamine (MDMA)-assisted psychotherapy for posttraumatic stress disorder: A systematic review and meta-analysis • Intracranial self-administration of MDMA into the ventral striatum of the rat: differential roles of the nucleus accumbens shell, core, and olfactory tubercle • Effect of a serotonin depleting regimen of 3, 4-methylenedioxymethamphetamine (MDMA) on the subsequent stimulation of acetylcholine release in the rat prefrontal … • Caffeine induces a profound and persistent tachycardia in response to MDMA (“Ecstasy”) administration • Role of the dopaminergic system in the acquisition, expression and reinstatement of MDMA-induced conditioned place preference in adolescent mice • Mechanisms mediating the ability of caffeine to influence MDMA ('Ecstasy')‐induced hyperthermia in rats • MDMA produces a delayed and sustained increase in the extracellular concentration of glutamate in the rat hippocampus • Neuroendocrine abnormalities in recreational ecstasy (MDMA) users: is it ecstasy or cannabis? • MDMA stimulus generalization to the 5-HT1A serotonin agonist 8-hydroxy-2-(di-n-propylamino) tetralin • Neurocognitive impairments in MDMA and other drug users: MDMA alone may not be a cognitive risk factor • Syllogistic reasoning performance in MDMA (Ecstasy) users. • “You Can't Just Give Your Best Mate a Massive Hug Every Day” Young Men, Play and MDMA • Long-term effects of repeated social stress on the conditioned place preference induced by MDMA in mice • Modification of Ag nanoparticles with mixed thiols for improved SERS detection of poorly adsorbing target molecules: detection of MDMA • MDMA: fact and fallacy, and the need to increase knowledge in both the scientific and popular press • Pharmacological aspects of the combined use of 3, 4‐methylenedioxymethamphetamine (MDMA, ecstasy) and gamma‐hydroxybutyric acid (GHB): a review of the … • Comparative potencies of 3,4‐methylenedioxymethamphetamine (MDMA) analogues as inhibitors of noradrenaline and 5‐HT transport in mammalian cell … • Sex‐dependent long‐term effects of adolescent exposure to THC and/or MDMA on neuroinflammation and serotoninergic and cannabinoid systems in rats • Ecstasy (MDMA)-addicted subjects show increased serum levels of brain-derived neurotrophic factor, independently from a rise of drug-induced psychotic symptoms. • Effects of 3, 4-methylenedioxymethamphetamine (MDMA,'Ecstasy') and para-methoxyamphetamine on striatal 5-HT when co-administered with moclobemide • Tracing the “event” of drug use:“Context” and the coproduction of a night out on MDMA • Prospective memory impairment in abstinent MDMA (" Ecstasy") users • Clandestine manufacture of 3, 4-methylenedioxymethylamphetamine (MDMA) by low pressure reductive amination. A mass spectrometric study of some reaction … • MDMA and parkinsonism • Acute effects of methylenedioxymethamphetamine (MDMA) on several complex brain functions in monkeys • The solid-state terahertz spectrum of MDMA (Ecstasy)–A unique test for molecular modeling assignments • Depression, impulsiveness, sleep, and memory in past and present polydrug users of 3, 4-methylenedioxymethamphetamine (MDMA, ecstasy) • Ecstasy (MDMA) and high prevalence psychiatric symptomatology: somatic anxiety symptoms are associated with polydrug, not ecstasy, use • MDMA-Like Stimulus Effects of Hallucinogens in Male Fawn–Hooded Rats • … –MS metabolomics reveals disturbed metabolic pathways in primary mouse hepatocytes exposed to subtoxic levels of 3, 4-methylenedioxymethamphetamine (MDMA) • Increased cortisol levels in hair of recent Ecstasy/MDMA users • An appraisal of the pharmacological and toxicological effects of a single oral administration of 3, 4‐methylenedioxymethamphetamine (MDMA) in the rat • Behavioral and neurochemical consequences of multiple MDMA administrations in the rat: role of individual differences in anxiety-related behavior • Visuo‐spatial working memory deficits in current and former users of MDMA ('ecstasy') • Acute psychomotor, memory and subjective effects of MDMA and THC co-administration over time in healthy volunteers • 3 cases of primary intracranial hemorrhage associated with “Molly”, a purified form of 3, 4-methylenedioxymethamphetamine (MDMA) • Examining the role of oxytocin in the interoceptive effects of 3, 4‐methylenedioxymethamphetamine (MDMA,'ecstasy') using a drug discrimination paradigm in the rat • Imaging brain activity in conscious monkeys following oral MDMA (“ecstasy”) • Rhabdomyolysis in MDMA intoxication: a rapid and underestimated killer.“Clean” ecstasy, a safe party drug? • 3, 4-methylenedioxymethamphetamine (MDMA) intoxication in an infant chronically exposed to cocaine • Synergistic toxicity of ethanol and MDMA towards primary cultured rat hepatocytes • Effects of salicylate on 3, 4-methylenedioxymethamphetamine (MDMA)-induced neurotoxicity in rats • MDMA powder, pills and crystal: the persistence of ecstasy and the poverty of policy • Response dynamics of midbrain dopamine neurons and serotonin neurons to heroin, nicotine, cocaine, and MDMA • Serotonin neurotoxicity in rats after combined treatment with a dopaminergic agent followed by a nonneurotoxic 3, 4-methylenedioxymethamphetamine (MDMA) … • 50-kHz calls in rats: Effects of MDMA and the 5-HT1A receptor agonist 8-OH-DPAT • Nonlinear pharmacokinetics of (±) 3, 4-methylenedioxymethamphetamine (MDMA) and its pharmacodynamic consequences in the rat • The intriguing effects of ecstasy (MDMA) on cognitive function in mice subjected to a minimal traumatic brain injury (mTBI) • Cerebral oedema after MDMA (" ecstasy") and unrestricted water intake. Hyponatraemia must be treated with low water input. • … method for simultaneous analysis of 10 amphetamine-, methamphetamine-and 3, 4-methylenedioxymethamphetamine-related (MDMA) analytes in human meconium • Chronic ecstasy (MDMA) use is associated with deficits in task-switching but not inhibition or memory updating executive functions • Serotonergic deficits and impaired passive-avoidance learning in rats by MDEA: a comparison with MDMA • Use of dynamically coated capillaries for the routine analysis of methamphetamine, amphetamine, MDA, MDMA, MDEA, and cocaine using capillary electrophoresis • Synthesis and cyclic voltammetry studies of 3, 4-methylenedioxymethamphetamine (MDMA) human metabolites • Intermittent ethanol exposure increases long-lasting behavioral and neurochemical effects of MDMA in adolescent mice • Serotonin 5-HT4 receptors in the nucleus accumbens are specifically involved in the appetite suppressant and not locomotor stimulant effects of MDMA ('ecstasy') • The A2a adenosine receptor modulates the reinforcement efficacy and neurotoxicity of MDMA • MDMA (ecstasy) effects in pubescent rats: males are more sensitive than females • Pharmacogenetic studies of change in cortisol on ecstasy (MDMA) consumption • Effects of fenfluramine, m-CPP and triazolam on repeated-acquisition in squirrel monkeys before and after neurotoxic MDMA administration • Conditioning following repeated exposure to MDMA in rats: Role in the maintenance of MDMA self-administration. • 'Is MDMA a human neurotoxin?': diverse views from the discussants • A Cannabinoid CB 1 Receptor Antagonist Ameliorates Impairment of Recognition Memory on Withdrawal from MDMA (Ecstasy) • Intravenous methamphetamine self-administration in rats: effects of intravenous or intraperitoneal MDMA co-administration • Modulation of methylenedioxymethamphetamine-induced striatal dopamine release by the interaction between serotonin and gamma-aminobutyric acid in the … • MDMA (“ecstasy”) impairs learning in the Morris Water Maze and reduces hippocampal LTP in young rats • Ecstasy (MDMA) exposure and neuropsychological functioning: a polydrug perspective • Direct determination of glucuronide and sulfate of 4-hydroxy-3-methoxymethamphetamine, the main metabolite of MDMA, in human urine • Optimization of extraction parameters for the chemical profiling of 3, 4-methylenedioxymethamphetamine (MDMA) tablets • Methods for the Analysis of 1-(3,4-Methylenedioxyphenyl)-2-Butanamine and N-Methy 1-(3,4-Methylenedioxyphenyl)- 2-Propanamine (MDMA) • Deaths involving MDMA and the concomitant use of pharmaceutical drugs • Acute psychomotor effects of MDMA and ethanol (co-) administration over time in healthy volunteers • Involvement of NMDA glutamate receptors in the acquisition and reinstatement of the conditioned place preference induced by MDMA • MDMA modifies active avoidance learning and recall in mice • Locomotor and pyretic effects of MDMA–ethanol associations in rats • MDMA pretreatment leads to mild chronic unpredictable stress-induced impairments in spatial learning. • Acute liver failure following the use of ecstasy (MDMA) • Time course analysis of the discriminative stimulus effects of the optical isomers of 3, 4-methylenedioxymethamphetamine (MDMA) • Hallucinogen persisting perception disorder and the serotonergic system: a comprehensive review including new MDMA-related clinical cases • Reinforcing effects of methylenedioxy amphetamine congeners in rhesus monkeys: are intravenous self-administration experiments relevant to MDMA … • The prevalence of MDMA/MDA in both hair and urine in drug users • Verbal memory deficits are correlated with prefrontal hypometabolism in 18 FDG PET of recreational MDMA users • Prior MDMA (Ecstasy) use is associated with increased basal ganglia–thalamocortical circuit activation during motor task performance in humans: An fMRI study • Central serous chorioretinopathy in a patient using methylenedioxymethamphetamine (MDMA) or “ecstasy” • Acute and carryover effects in mice of MDMA (“ecstasy”) administration during periadolescence • Occipital cortical proton MRS at 4 Tesla in human moderate MDMA polydrug users • The role of adenosine A1 and A2A receptors in the caffeine effect on MDMA-induced DA and 5-HT release in the mouse striatum • “Ecstasy” to addiction: Mechanisms and reinforcing effects of three synthetic cathinone analogs of MDMA • The impact of experimental design on assessing mechanism-based inactivation of CYP2D6 by MDMA (Ecstasy) • Second thoughts on 3, 4-methylenedioxymethamphetamine (MDMA) neurotoxicity • Effects of 3, 4‐methylenedioxymethamphetamine (MDMA) and its main metabolites on cardiovascular function in conscious rats • Attenuation of the disruptive effects of (+/-) 3, 4-methylene dioxymethamphetamine (MDMA) on delayed matching-to-sample performance in the rat. • Chronic stress enhances the corticosterone response and neurotoxicity to+ 3, 4-methylenedioxymethamphetamine (MDMA): the role of ambient temperature • Patterns of memory dysfunction in current and 2-year abstinent MDMA users • Oxytocin receptor gene variation predicts subjective responses to MDMA • Depressive symptomatology in young adults with a history of MDMA use: a longitudinal analysis • Receptor pharmacology of MDMA and related hallucinogens. • 3, 4-Methylenedioxymethamphetamine (MDMA) and other amphetamine derivatives • 3, 4-Methylenedioxymethamphetamine and 3, 4-methylenedioxyamphetamine destroy serotonin terminals in rat brain: quantification of neurodegeneration by … • A fatal case of myocardial damage due to misuse of the “designer drug” MDMA • Restraint as a stressor in mice:: Against the dopaminergic neurotoxicity of d-mdma, low body weight mitigates restraint-induced hypothermia and consequent … • Two-dimensional gas chromatography/electron-impact mass spectrometry with cryofocusing for simultaneous quantification of MDMA, MDA, HMMA, HMA, and MDEA … • The scheduling of MDMA: A pharmacist's perspective • The public health implications of MDMA use • Behavioural and neurotoxic long-lasting effects of MDMA plus cocaine in adolescent mice • Increased oxidative‐modifications of cytosolic proteins in 3, 4‐methylenedioxymethamphetamine (MDMA, ecstasy)‐exposed rat liver • Inhibitory effects of dopamine and methylenedioxymethamphetamine (MDMA) on glutamate-evoked firing of nucleus accumbens and caudate/putamen cells are … • GENETIC STUDY: 5‐HTTLPR polymorphism, mood disorders and MDMA use in a 3‐year follow‐up study • Mice with decreased cerebral dopamine function following a neurotoxic dose of MDMA (3, 4-methylenedioxymethamphetamine,“Ecstasy”) exhibit increased ethanol … • MDMA-induced impairment in primates: antagonism by a selective norepinephrine or serotonin, but not by a dopamine/norepinephrine transport inhibitor • 3, 4‐methylenedioxymethamphetamine (MDMA; Ecstasy) administration produces dose‐dependent neurochemical, endocrine and immune changes in the rat • … effects of 3, 4-methylenedioxypyrovalerone (MDPV) and 4-methylmethcathinone (mephedrone) in rats trained to discriminate MDMA or a d-amphetamine+ MDMA … • Epidemiology of MDMA and associated club drugs in the Seattle area • Age-dependent (+) MDMA-mediated neurotoxicity in mice • A PET study of effects of chronic 3, 4‐methylenedioxymethamphetamine (MDMA,“ecstasy”) on serotonin markers in Göttingen minipig brain • Repeated exposure to methylenedioxymethamphetamine (MDMA) alters nucleus accumbens neuronal responses to dopamine and serotonin • Distribution of methylenedioxymethamphetamine (MDMA) and methylenedioxyamphetamine (MDA) in postmortem and antemortem specimens • Dose-related effects of MDMA on psychomotor function and mood before, during, and after a night of sleep loss • Toxicity and deaths from 3, 4-methylenedioxymethamphetamine (" ecstasy") • Neurotoxicity of the psychedelic amphetamine, methylenedioxymethamphetamine. • Methamphetamine and methylenedioxymethamphetamine neurotoxicity: possible mechanisms of cell destruction • Methamphetamine neurotoxicity and striatal glutamate release: comparison to 3, 4-methylenedioxymethamphetamine • Subjective effects of 3, 4-methylenedioxymethamphetamine in recreational users • (±3, 4-Methylenedioxymethamphetamine Selectively Damages Central Serotonergic Neurons in Nonhuman Primates • (±) 3, 4-Methylenedioxymethamphetamine ('Ecstasy')-induced serotonin neurotoxicity: studies in animals • Oxidation of methamphetamine and methylenedioxymethamphetamine by CYP2D6 • Neurotoxicity of methamphetamine and 3, 4-methylenedioxymethamphetamine • Different glial response to methamphetamine-and methylenedioxymethamphetamine-induced neurotoxicity • In vitro and in vivo neurochemical effects of methylenedioxymethamphetamine on striatal monoaminergic systems in the rat brain • Depression of rat brain tryptophan hydroxylase activity following the acute administration of methylenedioxymethamphetamine • Rapid and transient inhibition of mitochondrial function following methamphetamine or 3, 4-methylenedioxymethamphetamine administration • A comparison of the physiological, behavioral, neurochemical and microglial effects of methamphetamine and 3, 4-methylenedioxymethamphetamine in the mouse • Methylenedioxymethamphetamine: a potentially neurotoxic amphetamine analogue • The demethylenation of methylenedioxymethamphetamine (“ecstasy”) by debrisoquine hydroxylase (CYP2D6) • Metabolism of methylenedioxymethamphetamine: formation of dihydroxymethamphetamine and a quinone identified as its glutathione adduct. • Antagonism of the neurotoxicity due to a single administration of methylenedioxymethamphetamine • Lasting neuropsychiatric sequelae of (+-) methylenedioxymethamphetamine ('ecstasy') in recreational users. • Is ecstasy an “empathogen”? Effects of±3, 4-methylenedioxymethamphetamine on prosocial feelings and identification of emotional states in others • Potentiation of 3, 4-methylenedioxymethamphetamine-induced dopamine release and serotonin neurotoxicity by 5-HT2 receptor agonists • Tissue distribution of methylenedioxymethamphetamine • MDMA-assisted therapy for severe PTSD: a randomized, double-blind, placebo-controlled phase 3 study
  • Effects of Hallucinogens and Other Drugs on Mood and Performance • Stanford Regulating Circuits of the Brain Study - MDMA • MDMA in Subjects With Moderate Hepatic Impairment and Subjects With Normal Hepatic Function • The Effects of MDMA on Prefrontal and Amygdala Activation in PTSD. • Bristol Imperial MDMA in Alcoholism Study • Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers (MT-2) • Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD (Canada) • A Multi-Site Study of MDMA-Assisted Psychotherapy for Eating Disorders • Effect of Methylenedioxymethamphetamine (MDMA) (Serotonin Release) on Fear Extinction • Evaluation of MDMA on Startle Response • Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD • Effects of MDMA on Emotional and Social Memories • MDMA-Assisted Psychotherapy in Veterans With Combat-Related, Refractory PTSD • -Methylenedioxymethamphetamine (MDMA, Ecstasy) Induced Changes in Drug Metabolism: Gender and Genetic Polymorphisms • Exploring Mechanisms of Action in MDMA-assisted Psychotherapy for PTSD • Influence of Bupropion on the Effects of MDMA • Study of the Effects of MDMA/Ecstasy on Water Regulation, Sleep, and Cognition. • Phase 2 Pilot Safety Study of MDMA-assisted Therapy for Social Anxiety in Autistic Adults • Pharmacological Interaction Between Carvedilol and Methylenedioxymethamphetamine (MDMA) • Pharmacological Interaction Between Clonidine and Methylenedioxymethamphetamine (MDMA) • Effects of MDMA on Social and Emotional Processing • MDMA-Assisted Cognitive-Behavioral Conjoint Therapy (CBCT) in Dyads in Which 1 Member Has Chronic PTSD • Pharmacological Interaction Between Pindolol and MDMA (3,4-Methylenedioxymethamphetamine) • A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD (MAPP1) • Role of Serotonin in Acute and Subacute MDMA Effects • Interaction Between Duloxetine and 3,4-Methylenedioxymethamphetamine (MDMA, Ecstasy) • MDMA-Assisted Psychotherapy for Anxiety Associated With a Life-Threatening Illness • A Multi-Site Phase 3 Study of MDMA-Assisted Psychotherapy for PTSD • Emotional Effects of Methylphenidate and MDMA in Healthy Subjects • Pharmacological Interaction Between Doxazosin and Methylenedioxymethamphetamine (MDMA) • Effects of MDMA and Methylphenidate on Social Cognition • Study Comparing Three Doses of MDMA Along With Therapy in Veterans With Posttraumatic Stress Disorder • Neurobiology and Pharmacokinets of Acute MDMA Administration • Additional MDMA-assisted Therapy for People Who Relapsed After MDMA-assisted Therapy Trial • Interaction Between Reboxetine and 3,4-Methylenedioxymethamphetamine: Pharmacodynamics (PD) and Pharmacokinetics (PK) • Randomized, Double-blind, Controlled of MDMA-assisted Psychotherapy in 12 Subjects With PTSD • Effects of Methylphenidate, Modafinil, and MDMA on Emotion-processing in Humans: A Pharmaco-fMRI Study • Psychological Effects of Methylenedioxymethamphetamine (MDMA) When Administered to Healthy Volunteers • Dose-Response Study of MDMA-assisted Psychotherapy in People With PTSD • A Multi-site Expanded Access Program for MDMA-assisted Psychotherapy for Patients With Treatment-resistant PTSD • Study of 3,4-Methylenedioxymethamphetamine-assisted Psychotherapy in People With Posttraumatic Stress Disorder • Randomized, Double-blind, Active Placebo-Controlled Pilot Study of MDMA-assisted Psychotherapy in People With Chronic PTSD • Effects of Drugs on Responses to Brain and Emotional Processes • Naturalistic Study Into the Hangover Effects of MDMA • Randomized Placebo-controlled Study of MDMA-assisted Therapy in People With PTSD - Israel • MDMA-Assisted Psychotherapy in People With Posttraumatic Stress Disorder • MDMA-assisted Therapy in People With Anxiety Related to Advanced Stage Cancer • Effect of Stimulant Drugs on Social Perception • Abuse Liability and Human Pharmacology of Mephedrone • The NeXT Study; The Netherlands XTC Toxicity Study • Role of Dopamine, Serotonin and 5-HT2A Receptors in Emotion Processing • Characterization of the Prosocial and Prosexual Effects of GHB • Mood Effects of Serotonin Agonists • Effects of MDMA Co-administration on the Response to LSD in Healthy Subjects • Open Label Multi-Site Study of Safety and Effects of MDMA-assisted Psychotherapy for Treatment of PTSD With Optional fMRI Sub-Study • A Multi-Site Open-Label Extension Study of MDMA-Assisted Psychotherapy for PTSD • Study Comparing Two Versus Three Active MDMA-assisted Sessions in U.S. Military Veterans With Chronic PTSD • Circulating Oxytocin Changes in Response to the Oxytocin System Stimulator MDMA in Patients With Diabetes Insipidus and Healthy Controls • Effects of MDMA-like Substances in Healthy Subjects • Investigation of Serotonin Neurotransmission in MDMA Users Using Combinated Dexfenfluramine Challenge and PET Imaging • Functional Brain Imaging in Recreational Users of Ecstasy • A Treatment Development Study of MDMA-Assisted Psychotherapy for PTSD • Food Effects on Bioavailability of MDMA in Healthy Volunteers • Social Anxiety MDMA-Assisted Therapy Investigation • Study of Safety and Effects of MDMA-assisted Therapy for Treatment of PTSD • Drug Effects on Interpersonal Interaction • Long-Term Safety and Effectiveness of Manualized MDMA-Assisted Therapy for the Treatment of Posttraumatic Stress Disorder • Correlates of Anxiety Associated With a Life-threatening Illness • Addiction in Intensive Cardiac Care Units • Clinical Pharmacology of MDA [3,4-methylenedioxyamphetamine] • Patient Doctor Lies • Personality and Drug Use (PDU) • Postpartum MDMA Co-occurring PTSD and OUD • Study of Feasibility and Safety of MDMA-Assisted Group Therapy for the Treatment of PTSD in Veterans • Acute Effects of R- and S-MDMA in Healthy Subjects • Sustaining Remission From PTSD Using Tuned Vibroacoustic Stimulation (TVS) Following MDMA-Assisted Psychotherapy • Effects of Stimulants on Behavioral and Neural Markers of Social Motivation, Ability, and Neural Markers of Social Function