Tryptamine and 5-hydroxytryptamine: Actions and interactions on cortical neurones in the rat

Abstract

The actions of iontophoretically applied tryptamine (T) and 5-hydroxytryptamine (5-HT) were compared on single neurones in the rat somatosensory cortex. The firing rate of the vast majority of neurones tested was depressed by T. However, 5-HT excited and depressed …