The inhibitory effect of norharman on morphine withdrawal syndrome in rats: comparison with ibogaine

SLT Cappendijk, D Fekkes, MR Dzoljic - Behavioural brain research, 1994 - Elsevier

Abstract

Abstract Norharman (20 mg/kg, ip) and ibogaine (40 mg/kg, ip) significantly attenuated naloxone (4 mg/kg, ip)-precipitated withdrawal syndrome in morphine-dependent rats. Several withdrawal signs, such as teeth-chattering, chewing, penile licking and diarrhoea …

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