The enzymic dephosphorylation and oxidation of psilocybin and pscilocin by mammalian tissue homogenates

Abstract

Incubation of psilocybin with rat kidney homogenates caused a rapid liberation of its-OH congener, psilocin, through the action of alkaline phosphatase. The psilocin thus formed underwent further degradation to form a blue-colored product. This last step appeared to be …