Psilocybin induces schizophrenia-like psychosis in humans via a serotonin-2 agonist action

Abstract

The dopamine (DA) hypothesis of schizophrenia has emphasized that a dopaminergic dysbalance is critical in the pathophysiology and treatment of schizophrenia. Increasing evidence, however, suggests that serotonin (5-HT) may also be implicated. Support for an …