Properties of ibogaine and its principal metabolite (12-hydroxyibogamine) at the MK-801 binding site of the NMDA receptor complex

DC Mash, JK Staley, JP Pablo, AM Holohean… - Neuroscience …, 1995 - Elsevier

Abstract

The putative anti-addiction alkaloid ibogaine and its principal metabolite 12-hydroxyibogamine appear to act at the (+)-5 methyl-10, 11-dihydro-5H-dibenzo [a, d] cycloheten-5–10-imine maleate (MK-801) binding site in the N-methyl-d-aspartate (NMDA) …

Last updated: Jul 27, 2020