NMDAR inhibition-independent antidepressant actions of ketamine metabolites

P Zanos, R Moaddel, PJ Morris, P Georgiou, J Fischell… - Nature, 2016 - nature.com

Abstract

Major depressive disorder affects around 16 per cent of the world population at some point in their lives. Despite the availability of numerous monoaminergic-based antidepressants, most patients require several weeks, if not months, to respond to these treatments, and many …

Last updated: Jul 27, 2020