Multiple serotonin receptors: differential binding of 5-hydroxytryptamine, lysergic acid diethylamide and spiroperidol

Abstract

[3 H] 5-Hydroxytryptamine (5-HT),[3 H] lysergic acid diethylamide (LSD) and [3 H] spiroperidol bind to membranes from the rat frontal cerebral cortex in a manner indicating a selective interaction with serotonin receptors. Differential drug potencies in competing for [3 …