Modulation of morphine-induced antinociception by ibogaine and noribogaine

AA Bagal, LB Hough, JW Nalwalk, SD Glick - Brain research, 1996 - Elsevier

Abstract

The potential modulation of morphine antinociception by the putative anti-addictive agent ibogaine and its active metabolite (noribogaine) was investigated in rats with the radiant heat tail-flick test. Ibogaine pretreatment (40 mg/kg, ip, 19 h) significantly decreased …

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