Metabolic engineering of Saccharomyces cerevisiae for the production of psilocybin and related tryptamine derivatives

Abstract

Psilocybin is a tryptamine-derived psychoactive alkaloid found mainly in the fungal genus Psilocybe, among others, and is the active ingredient in so-called “magic mushrooms”. Although its notoriety originates from its psychotropic properties and popular use as a …