Lysergic acid diethylamide and serotonin: direct actions on serotonin-containing neurons in rat brain

Abstract

Lysergic acid diethylamide (LSD) and serotonin (5HT) were applied directly by microiontophoresis to 5HT-containing neurons in the midbrain raphe nuclei. The firing of these neurons was markedly inhibited by both LSD and 5HT. The effects of LSD given …