Ketamine-induced NMDA receptor hypofunction as a model of memory impairment and psychosis

JW Newcomer, NB Farber, V Jevtovic-Todorovic… - …, 1999 - Elsevier

Abstract

Abstract N-methyl-D-aspartate (NMDA) glutamate receptor antagonists are reported to induce schizophrenia-like symptoms in humans, including cognitive impairments. Shortcomings of most previous investigations include failure to maintain steady-state …

Last updated: Jul 27, 2020