Ketamine: a paradigm shift for depression research and treatment

JH Krystal, CG Abdallah, G Sanacora, DS Charney… - Neuron, 2019 - Elsevier

Abstract

Ketamine is the first exemplar of a rapid-acting antidepressant with efficacy for treatment-resistant symptoms of mood disorders. Its discovery emerged from a reconceptualization of the biology of depression. Neurobiological insights into ketamine efficacy shed new light on …

Last updated: Jul 27, 2020