Interactions of tryptamine derivatives with serotonin transporter species variants implicate transmembrane domain I in substrate recognition

EM Adkins, EL Barker, RD Blakely - Molecular pharmacology, 2001 - ASPET

Abstract

The serotonin (5-hydroxytryptamine, 5-HT) transporter (SERT) is responsible for the inactivation of synaptic 5-HT and is also a target for multiple psychostimulants. Despite the critical role of SERT in 5-HT inactivation and psychostimulant response, many aspects of the …

Last updated: Jul 27, 2020