Ibogaine possesses a selective affinity for σ2 receptors

RH Mach, CR Smith, SR Childers - Life sciences, 1995 - Elsevier

Abstract

The alkaloid ibogaine is potentially useful to reduce craving for several drugs of abuse, but its mechanism of action is not known. In the current study, in vitro studies were conducted in order to determine the affinity of ibogaine for sigma receptors. Our results indicate that …

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