Ibogaine attenuation of morphine withdrawal in mice: role of glutamate N-methyl-D-aspartate receptors

Abstract

Ibogaine (IBO) is an alkaloid with putative antiaddictive properties, alleviating opiates dependence and withdrawal. The glutamate N-methyl-d-aspartate (NMDA) receptors have been implicated in the physiological basis of drug addiction; accordingly, IBO acts as a …