Failure of ibogaine to produce phencyclidine-like discriminative stimulus effects in rats and monkeys

HE Jones, H Li, RL Balster - Pharmacology Biochemistry and Behavior, 1998 - Elsevier

Abstract

The discriminative stimulus properties of ibogaine were investigated in rats trained to discriminate phencyclidine (PCP; 2.0 mg/kg, IP) from saline under a two-lever fixed-ratio (FR) 32 schedule of food reinforcement. Ibogaine (5.6–17.6 mg/kg, IP) showed a complete …

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