Excitotoxic insult due to ibogaine leads to delayed induction of neuronal NOS in Purkinje cells.

E O'Hearn, P Zhang, ME Molliver - NeuroReport, 1995 - europepmc.org

Abstract

Ibogaine causes degeneration of Purkinje cells (PKCs), presumably via activation of neurons in the inferior olive leading to release of glutamate at climbing fiber terminals. Following ibogaine administration, some Purkinje cells express NADPH-diaphorase and …

Last updated: Jul 27, 2020