Efficient one-pot synthesis of tryptamines and tryptamine homologues by amination of chloroalkynes

V Khedkar, A Tillack, M Michalik, M Beller - Tetrahedron letters, 2004 - Elsevier

Abstract

A new method was developed for the one-pot synthesis of substituted 3-(2-aminoethyl)-and 3-(3-aminopropyl) indoles from commercially available aryl hydrazines and chloroalkylalkynes. Various tryptamine derivatives were prepared directly in good yield with …

Last updated: Jul 27, 2020